Results 51 to 60 of about 3,207 (257)
Oceanologia, 2001 Microcystins and nodularin are potent hepatotoxins produced by fresh and seawater cyanobacteria. The persistence of three hepatotoxins - microcystin-LR, microcystin-RR and nodularin - was investigated in sterile BG-11 medium of different salinity and in ...
Hanna Mazur, Marcin Pliñski
doaj
Advanced Science, EarlyView.Periprosthetic joint infection establishes a sophisticated immunosuppressive network between CXCR4+ PMN‐MDSCs and Bregs, inducing profound CD8+ T cell paralysis. Alendronate effectively disrupts this CXCR4+ PMN‐MDSC–Breg axis by targeting STAT3, thereby restoring local immune surveillance.
Jintao Wu +9 more
wiley +1 more source
A 57 year old man with chronic renal failure and cardiac tamponade who developed ischemic hepatitis
Annals of Hepatology, 2006 Ischemic hepatitis is an infrequent entity, usually associated with low cardiac out put. We present a case of a 57 year-old man with chronic renal failure and cardiac tamponade who developed elevation of serum alanine transferase level of 5,054 U/L ...
Eric López-Méndez +7 more
doaj +1 more source
Advanced Science, EarlyView.This study identifies C4 as a lead inhibitor of the Lpt system. Notably, C4 potentiates colistin activity by disrupting LPS transport and remodeling phospholipid homeostasis, revealing a functional interplay between the Lpt and Mla systems. These findings establish a mechanistic link between Lpt inhibition and membrane lipid remodeling, positioning Lpt–
Jianya Luo +6 more
wiley +1 more source
Toxins, 2013 Microcystins, which are cyclic heptapeptides produced by some cyanobacterial species from algal blooms, strongly inhibit serine/threonine protein phosphatase and are known as hepatotoxins.
Kumiko Shimizu +8 more
doaj +1 more source
Advanced Science, EarlyView.A vascularized liver‐on‐a‐microsphere system is developed to recreate lobule‐like cellular organization and endothelial barrier function within compartmentalized hydrogel particles. The platform enhances hepatic performance and reveals alanine‐glucose cycle activation linked to improved detoxification capacity, offering a high‐throughput microscale ...
Jingyang Li +9 more
wiley +1 more source
Cyanotoxins in Serbia and water treatment procedures for their elimination [PDF]
Geographica Pannonica, 2012 Cyanotoxins are secondary metabolites produced by cyanobacteria, mainly as a result of eutrofication and water quality deterioration. The most common cyanotoxins are cyclic peptide hepatotoxins called microcystins.
Tokodi Nada +3 more
doaj
Renmin Zhujiang, 2022 Microcystins (MCs) are a common class of hepatotoxins mainly produced upon the apoptosis of freshwater blue-green algae and are highly poisonous to human beings and aquatic life.It is of great significance to establish an accurate and rapid detection ...
ZHANG Panwei +6 more
doaj
Advanced Science, EarlyView.A pneumatically actuated multi‐tissue microphysiological system is integrated with AI‐based machine vision and automatic sampling and replenishment systems. The platform allows for the emulation of translationally relevant long‐term pharmacokinetic exposure scenarios for multiple weeks while enabling longitudinal monitoring of response biomarkers ...
Jibbe Keulen +15 more
wiley +1 more source
The Fate of Microcystins in the Environment and Challenges for Monitoring
Toxins, 2014 Microcystins are secondary metabolites produced by cyanobacteria that act as hepatotoxins in higher organisms. These toxins can be altered through abiotic processes, such as photodegradation and adsorption, as well as through biological processes via ...
Justine R. Schmidt +2 more
doaj +1 more source