Results 61 to 70 of about 4,323 (190)

Nodularia spumigena Peptides—Accumulation and Effect on Aquatic Invertebrates

open access: yesToxins, 2015
Thus far, the negative effects of Nodularia spumigena blooms on aquatic organisms have been mainly attributed to the production of the hepatotoxic nodularin (NOD). In the current work, the accumulation of other N.
Hanna Mazur-Marzec   +5 more
doaj   +1 more source

Comparative Studies on the pH Dependence of DOW of Microcystin-RR and -LR Using LC-MS

open access: yesThe Scientific World Journal, 2011
Microcystins (MCs) are well known worldwide as hepatotoxins produced by cyanobacteria, but little is known about the physicochemical properties of these compounds.
Gaodao Liang   +3 more
doaj   +1 more source

Drug-induced liver injury. Part I: Classification, diagnosis and treatment

open access: yesClinical & Experimental Hepatology
Drug-induced liver injury (DILI) is a growing clinical problem. Antibiotics remain the most common cause of DILI in Europe. Their clinical spectrum is very broad, from asymptomatic to acute liver failure. Currently, DILI is categorized as hepatocellular (
Dorota M. Kozielewicz   +2 more
doaj   +1 more source

High Content Screening of Corning® HepatoCells for Hepatotoxicity

open access: yes, 2016
Revealing compounds that have a negative impact on the liver early in a drug development campaign is important in drug discovery. Drug induced liver injury is one of the most cited causes of drug candidate failure, and is often the reason for withdrawal ...
Ute Vespermann (5201590), Ute Vespermann
core   +1 more source

Bioactive Toxins

open access: yes, 2007
Fatal intoxications of fish, water birds and domestic animals in aquatic habitats are frequently observed with blooms of cyanobacteria. The latter produces two types of toxins : cytotoxins & biotoxins and a few antibiotics (allelopaths) such as ...
Jaya Garg   +3 more
core   +1 more source

Microcystin class of toxins: health effects and safety of drinking water supplies

open access: yes, 1994
The microcystins are produced by several species of common planktonic cyanobacteria found in surface waters, but their biological function remains unknown. The microcystins have been shown to be extremely potent hepatotoxins in a variety of experimental
S. E. Hrudey   +2 more
core   +1 more source

Cytochrome P450 2A5 and Bilirubin: Mechanisms of Gene Regulation and Cytoprotection [PDF]

open access: yes, 2013
Murine cytochrome P450 2A5 (CYP2A5) is an interesting enzyme for its unique regulation and its involvement in liver injury caused by various well-known pathological conditions or hepatotoxins.
Sangsoo Daniel, Kim
core  

Bioactive Toxins

open access: yes, 2018
Fatal intoxications of fish, water birds and domestic animals in aquatic habitats are frequently observed with blooms of cyanobacteria. The latter produces two types of toxins : cytotoxins & biotoxins and a few antibiotics (allelopaths) such as ...
HK Garg (5325161)
core   +1 more source

各種肝臓毒による急性肝障害時のラット血清中α-フェトプロティン値の動態

open access: yes, 1998
Changes of serum α-fetoprotein (AFP), transaminase (GOT,GPT) and bilrubin levels after a single administration of carbon tetrachloride, galactosamine, α-naphthylisothiocyanate or ethionine were studied in rats 4-5 weeks old. In liver-injured rats with or
柴田, 浩   +2 more
core  

Cyanobacterial Toxins

open access: yes, 2009
Lethal intoxications of animals dwelling in aquatic habitats are recurrently observed with blooms of cyanobacteria. The latter produces two types of toxins : cytotoxins & biotoxins and a few antibiotics (allelopaths) such as acutiphycins, indolcarbazoles,
Jaya Garg   +3 more
core   +1 more source

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