Results 71 to 80 of about 4,021 (283)

Use of Clotrimazole in Finfish Aquaculture: Mechanistic Insights, Limitations, and Future Directions for Antifungal Therapy

open access: yesAnimal Research and One Health, EarlyView.
This review critically evaluates clotrimazole as a potential antifungal for finfish aquaculture, highlighting strong mechanistic and in vitro efficacy against aquatic mycoses alongside major gaps in in vivo evidence, toxicokinetics, residue safety, and environmental risk, outlining priorities for responsible therapeutic development and regulatory ...
Arya Sen   +2 more
wiley   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

open access: yes, 2022
Hepatology, EarlyView.
Robert J. Fontana   +6 more
wiley   +1 more source

Effects of the Amino Acid Constituents of Microcystin Variants on Cytotoxicity to Primary Cultured Rat Hepatocytes

open access: yesToxins, 2013
Microcystins, which are cyclic heptapeptides produced by some cyanobacterial species from algal blooms, strongly inhibit serine/threonine protein phosphatase and are known as hepatotoxins.
Kumiko Shimizu   +8 more
doaj   +1 more source

Increased Risk of Intrahepatic Cholestasis of Pregnancy in Women With Systemic Lupus Erythematosus Exposed to Azathioprine

open access: yesArthritis &Rheumatology, EarlyView.
Objective To evaluate the risk of intrahepatic cholestasis of pregnancy (ICP) in azathioprine (AZA)–exposed versus unexposed systemic lupus erythematosus (SLE) pregnancies within the multicenter prospective Lupus in Pregnancy (LEGACY) cohort. Methods LEGACY is conducted at Systemic Lupus International Collaborating Clinics in Canada, South Korea, Peru,
Reem Farhat   +14 more
wiley   +1 more source

Cyanotoxins in Serbia and water treatment procedures for their elimination [PDF]

open access: yesGeographica Pannonica, 2012
Cyanotoxins are secondary metabolites produced by cyanobacteria, mainly as a result of eutrofication and water quality deterioration. The most common cyanotoxins are cyclic peptide hepatotoxins called microcystins.
Tokodi Nada   +3 more
doaj  

Determination of Eight Microcystins in Water by Ultra-High Performance Liquid Chromatography-Tandem Mass Spectrometry

open access: yesRenmin Zhujiang, 2022
Microcystins (MCs) are a common class of hepatotoxins mainly produced upon the apoptosis of freshwater blue-green algae and are highly poisonous to human beings and aquatic life.It is of great significance to establish an accurate and rapid detection ...
ZHANG Panwei   +6 more
doaj  

SIRT3 is required for liver regeneration but not for the beneficial effect of nicotinamide riboside

open access: yesJCI Insight, 2021
Liver regeneration is critical to survival after traumatic injuries, exposure to hepatotoxins, or surgical interventions, yet the underlying signaling and metabolic pathways remain unclear.
Sarmistha Mukherjee   +9 more
doaj   +1 more source

The Fate of Microcystins in the Environment and Challenges for Monitoring

open access: yesToxins, 2014
Microcystins are secondary metabolites produced by cyanobacteria that act as hepatotoxins in higher organisms. These toxins can be altered through abiotic processes, such as photodegradation and adsorption, as well as through biological processes via ...
Justine R. Schmidt   +2 more
doaj   +1 more source

CYCLIC PEPTIDE HEPATOTOXINS FROM FRESH-WATER CYANOBACTERIAL (BLUE-GREEN-ALGAE) WATERBLOOMS COLLECTED IN CENTRAL CHINA

open access: yes, 1991
Toxic cyanobacteria (blue-green algae) waterblooms have been found in several Chinese water bodies since studies began there in 1984. Waterbloom samples for this study contained Anabaena circinalis, Microcystis aeruginosa and Oscillatoria sp.
HANG-HAO LI   +3 more
core  

Selection of gonadotrophin surge attenuating factor phage antibodies by bioassay [PDF]

open access: yes, 2005
Peer ...
Fowler, Paul Alfred Francois   +15 more
core   +1 more source

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