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Infection involves the utilization of host nutritional resources by the pathogen. Genetic, experimental, and clinical evidence supports the critical role of iron as a focus for both pathogen attack and host defense. The molecular basis of how mammals regulate iron transport to maintain homeostasis, and in response to infection, has been well ...
Crisell, D, Talbot, N, Drakesmith, H
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Hepcidin, the iron watcher

Biochimie, 2009
Hepcidin, a peptide hormone produced by the liver, constitutes the master regulator of iron homeostasis in mammals allowing iron adaptation according to the body iron needs. In recent years there has been important breakthrough in our knowledge of hepcidin regulation that has also implications for understanding the physiopathology of human iron ...
Lydie, Viatte, Sophie, Vaulont
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Hepcidin in iron metabolism

Current Opinion in Hematology, 2004
Hepcidin is a recently discovered hepatic peptide that regulates intestinal iron absorption as well as maternal-fetal iron transport across the placenta. It probably also affects the release of iron from hepatic stores and from macrophages involved in the recycling of iron from hemoglobin.
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Hepcidin