Results 71 to 80 of about 2,189 (194)

Emerging Role of Ferroptosis in Diabetes and Associated Complications: When Metabolic Dysregulation Meets Cell Death

open access: yesCell Proliferation, EarlyView.
This study identifies ferroptosis as a key driver of diabetes and its complications via iron metabolism and lipid peroxidation, elucidates organelle interactions underlying cell vulnerability, and provides insights for targeted therapies against metabolic disorders.
Zheng Wang   +10 more
wiley   +1 more source

Estrogen Modulates Hepatic Gene Expression and Survival of Rainbow Trout Infected with Pathogenic Bacteria Yersinia ruckeri [PDF]

open access: yes, 2018
In the aquatic environment, fish are exposed to various stimuli at once and have developed different response mechanisms to deal with these multiple stimuli.
Afanasyev, Sergey   +6 more
core  

An overview of antimicrobial peptides and the latest advances in their development [PDF]

open access: yes, 2020
INTRODUCTION: The recent dramatic increase in the incidence of antimicrobial resistance has been recognized by organizations such as the United Nations and World Health Organization as well as the governments of the USA and several European countries.
Fusté i Domínguez, Ester   +4 more
core   +1 more source

Identification of Common Blood Metabolic Derangements Using Magnetic Resonance Signatures of the Pancreas and Liver

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aim To investigate whether common disturbances of glucose and lipid metabolism can be automatically identified from magnetic resonance signatures of the pancreas and liver. Methods In this proof‐of‐principle study, 100 individuals with a history of pancreatitis—a relatively homogeneous population at risk for metabolic derangements—underwent ...
Wandia Kimita   +5 more
wiley   +1 more source

Hemojuvelin: The Hepcidin Story Continues [PDF]

open access: yesKidney and Blood Pressure Research, 2009
Hemojuvelin (HJV) is a membrane protein that is responsible for the iron overload condition known as juvenile hemochromatosis. HJV, highly expressed in the liver, skeletal muscle and heart, seems to play a role in iron absorption and release from cells and has anti-inflammatory properties.
openaire   +2 more sources

Assessment of severity of cystic fibrosis in children depending on the vitamin D status [PDF]

open access: yes, 2020
Introduction.Severity of CF depends on speed of lung disease progression which depend on many factors. Patients with CF suffer from vitamin D deficiency that could contribute to decreasing of lung function due to anti-inflammatory and antimicrobial ...
Demianyshyna, Valeriia, Dudnyk, Veronika
core   +2 more sources

National Bleeding Disorder Foundation Clinical Practice Recommendations for Laboratory Screening of Iron Deficiency With and Without Anemia in the Inherited Bleeding Disorders Population

open access: yesHaemophilia, EarlyView.
ABSTRACT Introduction The National Bleeding Disorder Foundation (NBDF) Medical and Scientific Advisory Council (MASAC) was formed in 1954 and issues recommendations and advisories pertinent to the bleeding disorders community. MASAC is comprised of > 25 rotating members from different medical disciplines and lived experience experts.
Glaivy Batsuli   +15 more
wiley   +1 more source

Regulators of hepcidin expression

open access: yes, 2019
Iron, an essential nutrient, is required for many biological processes but is also toxic in excess. The lack of a mechanism to excrete excess iron makes it crucial for the body to regulate the amount of iron absorbed from the diet. This regulation is mediated by the hepatic hormone hepcidin.
Roth, Marie-Paule   +2 more
openaire   +4 more sources

Signaling pathways regulating hepcidin [PDF]

open access: yes, 2019
Since its discovery in 2001, there have been a number of important discoveries and findings that have increased our knowledge about the functioning of hepcidin. Hepcidin, the master iron regulator has been shown to be regulated by a number of physiological stimuli and their associated signaling pathways.
Rishi, Gautam, Subramaniam, V. Nathan
openaire   +3 more sources

The effect of nonsurgical periodontal therapy on hepcidin and on inflammatory and iron marker levels

open access: yesBrazilian Oral Research
Serum hepcidin levels may increase in response to infection and inflammation. The present study investigated the effect of nonsurgical periodontal therapy (NSPT) on levels of serum hepcidin, inflammatory markers, and iron markers. An interventional study
Sandra Augusta de Moura LEITE   +9 more
doaj   +1 more source

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