Results 61 to 70 of about 1,887 (167)

Iron Overload: Pathophysiology, Diagnosis and Monitoring

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Iron overload is associated with significant health risks, underscoring the importance of understanding its pathophysiology as well as establishing accurate diagnostic and monitoring methods. Chronic iron overload is associated with either genetic disorders characterized by excessive iron accumulation (hereditary hemochromatosis), or is ...
Elena Chatzikalil, Polyxeni Delaporta, Konstantinos Bistas, Antonis Kattamis   +3 more
wiley   +1 more source

The effect of nonsurgical periodontal therapy on hepcidin and on inflammatory and iron marker levels

Brazilian Oral Research
Serum hepcidin levels may increase in response to infection and inflammation. The present study investigated the effect of nonsurgical periodontal therapy (NSPT) on levels of serum hepcidin, inflammatory markers, and iron markers. An interventional study
Sandra Augusta de Moura LEITE, Rosana Costa CASANOVAS, Vandilson Pinheiro RODRIGUES, Adriana de Fátima Vasconcelos PEREIRA, Teresa Cristina Alves FERREIRA, Flávia Raquel Fernandes do NASCIMENTO, Johnny Ramos do NASCIMENTO, Isaac Suzart GOMES-FILHO, Marcus Gomes BASTOS, Antonio Luiz Amaral PEREIRA   +9 more
doaj   +1 more source

Haemochromatosis ‐ a modern clinician’s guide

Internal Medicine Journal, EarlyView.
Abstract Haemochromatosis is an inherited disorder of iron metabolism affecting approximately 100 000 Australians. Iron overload may result in end organ dysfunction, most commonly manifesting as chronic liver disease, arthropathy and endocrinopathies. End organ complications can be prevented, minimised or reversed, with early diagnosis and initiation ...
James G. Fiori, John K. Olynyk
wiley   +1 more source

Serum hepcidin in clinical specimens [PDF]

British Journal of Haematology, 2003
Summary. The hepatic antimicrobial protein, hepcidin, is implicated in duodenal iron absorption and mobilization. Overexpression of the hepcidin gene is associated with a hypoferraemic, microcytic, iron‐refractory anaemia. On the basis of these observations, it has been proposed that hepcidin is a mediator of the common clinical syndrome, anaemia of ...
Gail, Dallalio, Thomas, Fleury, Robert T, Means   +2 more
openaire   +2 more sources

Impact of Expanded Hemodialysis on Inflammation and Iron Metabolism in Chronic Hemodialysis Patients

Seminars in Dialysis, EarlyView.
ABSTRACT Microinflammation and functional iron deficiency are major contributors to anemia and treatment burden in maintenance hemodialysis (HD). Medium cutoff (MCO) membranes enhance the removal of middle‐ and large‐sized solutes implicated in these pathways, yet real‐world data using routinely measured inflammatory and iron‐related markers are scarce.
Berrak Itır Aylı, Gülay Ulusal Okyay, Mehmet Deniz Aylı   +2 more
wiley   +1 more source

Parenteral iron—Does it increase infection risk?

Vox Sanguinis, EarlyView.
Abstract Background and Objectives Iron deficiency (ID) and iron deficiency anaemia (IDA) are prevalent conditions impacting various patient populations, both surgical and non‐surgical conditions. The advent of patient blood management (PBM) has promoted intravenous (IV) iron therapy as an alternative to oral iron and blood transfusions.
Joyisa Deb, Aswin K. Mohan, Suhasini Sil, Suvro Sankha Datta, Yoghini Nagandran, Manideepa Maji, Mohammad Kamrul Hassan Majumder, Saikat Mandal   +7 more
wiley   +1 more source

Hepcidin promotes oral ulcer healing via amphiregulin production in rats

Journal of Dental Sciences
Background/purpose: Hepcidin is an antimicrobial peptide that regulates iron metabolism. Recently, hepcidin was reported to promote wound healing. However, the mechanism underlying hepcidin signaling in the oral mucosa remains unclear.
Naoto Taguchi, Suzuro Hitomi, Hitoshi Sato, Yoshinori Hayashi, Ikuko Shibuta, Koichi Iwata, Tatsuo Shirota, Masamichi Shinoda   +7 more
doaj   +1 more source

Hypoxia and hypercapnia elicit overlapping but distinct skeletal muscle toxicities

The Journal of Physiology, EarlyView.
Abstract figure legend Hypoxia and hypercapnia cause overlapping skeletal muscle phenotypes, including atrophy, change in myofibre metabolic profile and myogenic response to injury. Both signals operate via distinct cellular pathways. Abstract Skeletal muscle dysfunction is strongly associated with elevated mortality in acute and chronic pulmonary ...
Joseph Balnis, Ariel Jaitovich
wiley   +1 more source

Improving the Evaluation and Management of Transfusion‐Related Iron Overload in Children, Adolescents, and Young Adults Following Cancer Treatment or Hematopoietic Stem Cell Transplantation

Pediatric Blood &Cancer, Volume 73, Issue 6, June 2026.
ABSTRACT Background Transfusion‐related iron overload (TRIO) is a late effect of therapy impacting survivors of childhood cancer and hematopoietic stem cell transplantation (HSCT) who receive frequent packed red blood cell (pRBC) transfusions. Surprisingly, there are no accepted guidelines to assist providers in identifying and treating at‐risk ...
Luke Gingell, Allison Close, Guoli Zhou, Troy C. Quigg   +3 more
wiley   +1 more source

Chitosan-grape seed oil nanoemulsion enriched diet promotes performance, antioxidant-immune metrics and modifies immune- gene action and morphological architecture in Nile tilapia against Aeromonas veronii

Aquaculture Reports
The development of nanoemulsions has garnered interest for their potential applications. Currently, there is no data on the effects of chitosan grape seed oil nanoemulsion (CGON) on Nile tilapia.
Shaimaa A.A. Ahmed, Fatma Mahsoub, Samar A. El Gamal, Tarek Khamis, Khaled Yehia Faroh, Abdelwahab A. Abdelwarith, Elsayed M. Younis, Mai F. Saad, Hanaa S. Ali, Simon J. Davies, Adham Al-Sagheer, Walaa El-Houseiny   +11 more
doaj   +1 more source