Results 61 to 70 of about 1,905 (175)

Clinical Efficacy of Vitamin D Supplements for the Treatment of Anemia in Patients With Chronic Kidney Disease: A Systematic Review and Meta‐Analysis

Hemodialysis International, EarlyView.
ABSTRACT Objective To conduct a meta‐analysis of clinical randomized controlled studies related to vitamin D supplements for the treatment of anemia in patients with chronic kidney disease (CKD), to evaluate the clinical efficacy of vitamin D supplements for CKD patients complicated with anemia.
Xiaodong Wanyan, Jiayun Xu
wiley   +1 more source

Hemojuvelin: The Hepcidin Story Continues [PDF]

Kidney and Blood Pressure Research, 2009
Hemojuvelin (HJV) is a membrane protein that is responsible for the iron overload condition known as juvenile hemochromatosis. HJV, highly expressed in the liver, skeletal muscle and heart, seems to play a role in iron absorption and release from cells and has anti-inflammatory properties.
openaire   +2 more sources

Iron Overload: Pathophysiology, Diagnosis and Monitoring

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Iron overload is associated with significant health risks, underscoring the importance of understanding its pathophysiology as well as establishing accurate diagnostic and monitoring methods. Chronic iron overload is associated with either genetic disorders characterized by excessive iron accumulation (hereditary hemochromatosis), or is ...
Elena Chatzikalil, Polyxeni Delaporta, Konstantinos Bistas, Antonis Kattamis   +3 more
wiley   +1 more source

Parenteral iron—Does it increase infection risk?

Vox Sanguinis, EarlyView.
Abstract Background and Objectives Iron deficiency (ID) and iron deficiency anaemia (IDA) are prevalent conditions impacting various patient populations, both surgical and non‐surgical conditions. The advent of patient blood management (PBM) has promoted intravenous (IV) iron therapy as an alternative to oral iron and blood transfusions.
Joyisa Deb, Aswin K. Mohan, Suhasini Sil, Suvro Sankha Datta, Yoghini Nagandran, Manideepa Maji, Mohammad Kamrul Hassan Majumder, Saikat Mandal   +7 more
wiley   +1 more source

Hepcidin and Anemia: A Tight Relationship [PDF]

Frontiers in Physiology, 2019
Hepcidin, the master regulator of systemic iron homeostasis, tightly influences erythrocyte production. High hepcidin levels block intestinal iron absorption and macrophage iron recycling, causing iron restricted erythropoiesis and anemia. Low hepcidin levels favor bone marrow iron supply for hemoglobin synthesis and red blood cells production ...
Alessia Pagani, Antonella Nai, Antonella Nai, Laura Silvestri, Laura Silvestri, Clara Camaschella   +5 more
openaire   +3 more sources

Hepcidin promotes oral ulcer healing via amphiregulin production in rats

Journal of Dental Sciences
Background/purpose: Hepcidin is an antimicrobial peptide that regulates iron metabolism. Recently, hepcidin was reported to promote wound healing. However, the mechanism underlying hepcidin signaling in the oral mucosa remains unclear.
Naoto Taguchi, Suzuro Hitomi, Hitoshi Sato, Yoshinori Hayashi, Ikuko Shibuta, Koichi Iwata, Tatsuo Shirota, Masamichi Shinoda   +7 more
doaj   +1 more source

Hypoxia and hypercapnia elicit overlapping but distinct skeletal muscle toxicities

The Journal of Physiology, EarlyView.
Abstract figure legend Hypoxia and hypercapnia cause overlapping skeletal muscle phenotypes, including atrophy, change in myofibre metabolic profile and myogenic response to injury. Both signals operate via distinct cellular pathways. Abstract Skeletal muscle dysfunction is strongly associated with elevated mortality in acute and chronic pulmonary ...
Joseph Balnis, Ariel Jaitovich
wiley   +1 more source

Improving the Evaluation and Management of Transfusion‐Related Iron Overload in Children, Adolescents, and Young Adults Following Cancer Treatment or Hematopoietic Stem Cell Transplantation

Pediatric Blood &Cancer, Volume 73, Issue 6, June 2026.
ABSTRACT Background Transfusion‐related iron overload (TRIO) is a late effect of therapy impacting survivors of childhood cancer and hematopoietic stem cell transplantation (HSCT) who receive frequent packed red blood cell (pRBC) transfusions. Surprisingly, there are no accepted guidelines to assist providers in identifying and treating at‐risk ...
Luke Gingell, Allison Close, Guoli Zhou, Troy C. Quigg   +3 more
wiley   +1 more source

Regulators of hepcidin expression

, 2019
Iron, an essential nutrient, is required for many biological processes but is also toxic in excess. The lack of a mechanism to excrete excess iron makes it crucial for the body to regulate the amount of iron absorbed from the diet. This regulation is mediated by the hepatic hormone hepcidin.
Roth, Marie-Paule, Meynard, Delphine, Coppin, Hélène   +2 more
openaire   +4 more sources

Chitosan-grape seed oil nanoemulsion enriched diet promotes performance, antioxidant-immune metrics and modifies immune- gene action and morphological architecture in Nile tilapia against Aeromonas veronii

Aquaculture Reports
The development of nanoemulsions has garnered interest for their potential applications. Currently, there is no data on the effects of chitosan grape seed oil nanoemulsion (CGON) on Nile tilapia.
Shaimaa A.A. Ahmed, Fatma Mahsoub, Samar A. El Gamal, Tarek Khamis, Khaled Yehia Faroh, Abdelwahab A. Abdelwarith, Elsayed M. Younis, Mai F. Saad, Hanaa S. Ali, Simon J. Davies, Adham Al-Sagheer, Walaa El-Houseiny   +11 more
doaj   +1 more source