Results 121 to 130 of about 1,118,240 (282)
مجلة اداب ذي قارStudying historical figures is one of the most prominent and important research areas for understanding historical events and the causes of major transformations in making historical events.
Dr. Maha Abdulrahman Hussein
doaj +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Metaphors of 'Worldly Life' and 'Hereafter' in the Holy Quran: A Conceptual Approach
مجلة اداب ذي قارConceptual Metaphor is a theory that is associated with cognitive semantics, in which metaphor is seen as a process of understanding one conceptual domain in terms of another.
Aziz Khalaf Abid Saleh +1 more
doaj +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
¿Sin Dolores? La ética política de Maquiavelo y Weber en The Sweet Hereafter
Revista Enfoques, 2009 This article, on one hand, seeks to analyze the relationship between ethics and politics through Atom Egoyan's film, The Sweet Hereafter ; and on the other hand, it means to demonstrate that theoretical reflection on certain questions not only can and ...
Javier Franzé
doaj
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Case study India responds to international food safety requirements [PDF]
"As awareness grows about food safety issues, the need for countries to provide greater assurance about the safety and quality of food also grows....This brief reviews (1) how India utilizes the international framework for food safety standards set forth
Sareen, Shashi
core
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source