Results 111 to 120 of about 317,082 (297)
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Beli̇ef i̇n the hereafter percepti̇ons of mi̇ddle school students (Karaman sample)
Yüksek Lisans Tezi. YÖK Tez Merkezi No: 407582Bu araştırmanın amacı, ortaokul düzeyinde eğitim-öğretim gören öğrencilerin âhiret inancı algılarını araştırmak, Din Kültürü ve Ahlak Bilgisi Dersi müfredatında belirlenen ahiret inancı ile ilgili amaç ve ...
Geçit, Halil
core
Lisansüstü Eğitim Enstitüsü, Temel İslam Bilimleri Ana Bilim DalıKur'an'ın tabileri için dünya hayatını modellerken kullanmış olduğu metotlardan bir tanesi ebedi hayat algısını sürekli canlı tutmaktır.
Köse, Akif
core
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Resurrection and the hereafter : A decisive proof of their reality
This book with its exquisite logic, not only proves decisively the existence of life after death, but it also makes clear the relevance of our states in the hereafter.
Said, Bediuzzaman Nursi
core
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Studying historical figures is one of the most prominent and important research areas for understanding historical events and the causes of major transformations in making historical events.
Dr. Maha Abdulrahman Hussein
doaj +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Christian George approaches Charles Spurgeon’s sermons in terms of a preached Christology, that is, a Christology not confined to dogmatics but operative in preaching.
George, Christian
core

