Results 161 to 170 of about 3,171 (206)
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Review of hereditary angioedema
LymphoSign Journal, 2016Hereditary angioedema (HAE) is a rare disease caused by deficiency of C1 esterase inhibitor (C1-INH). It is an autosomal dominant disease caused by a variety of mutations in the C1-INH gene. C1-INH is an important regulator of several pathways. One pathway it affects is the kallikrein–kinin pathway, which results in the generation of bradykinin ...
Lisa W. Fu +3 more
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Southern Medical Journal, 1992
Hereditary angioedema is a rare disease resulting from a lack of functional C1 esterase inhibitor (C1 INH). Several genetic defects can cause decreased production of the protein or the synthesis of a biologically inactive form. A similar, acquired condition is occasionally seen, associated with malignancies or as an autoimmune process. Disease severity
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Hereditary angioedema is a rare disease resulting from a lack of functional C1 esterase inhibitor (C1 INH). Several genetic defects can cause decreased production of the protein or the synthesis of a biologically inactive form. A similar, acquired condition is occasionally seen, associated with malignancies or as an autoimmune process. Disease severity
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An Update on Hereditary Angioedema
Advanced Emergency Nursing Journal, 2011Hereditary angioedema affects approximately 1 in 50,000 individuals without gender or ethnic preference. Hereditary angioedema is caused by a decreased level (type I) or function (type II) of C1 inhibitor. Patients experience repeated episodes of angioedema involving sites that include the face, extremities, gastrointestinal tract, and larynx ...
Marylee, Verdi, Marcus, Shaker
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Journal of Neuroscience Nursing, 2007
Hereditary angioedema (HAE) is a condition that results from an autosomal dominant trait. It manifests as attacks of swelling involving the extremities, trunk, abdominal viscera, face, neck, or airway. The attacks may occur spontaneously, without any identifiable trigger, or may be the result of a specific trigger, such as a minor tissue trauma.
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Hereditary angioedema (HAE) is a condition that results from an autosomal dominant trait. It manifests as attacks of swelling involving the extremities, trunk, abdominal viscera, face, neck, or airway. The attacks may occur spontaneously, without any identifiable trigger, or may be the result of a specific trigger, such as a minor tissue trauma.
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Hereditary angioedema and aortitis
Klinische Wochenschrift, 1987A 28-year-old male with hereditary angioedema died of an extensive stroke. Autopsy revealed cicatricial aortitis with narrowing of the coronary ostia, myocardial infarctions, and a left ventricular mural thrombus. There was neither acute inflammation of the aorta nor systemic vasculitis.
U, Hoffmann +5 more
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Treatment of hereditary angioedema
Klinische Wochenschrift, 1978The purpose of this study was to report the results of different treatments in 20 patients with hereditary angioedema. Effectiveness of tranexamic acid in preventing swellings was evaluated in 15 patients: in all but 3 subjects tranexamic acid was effective without serious side effects. 15 severe attacks of edema were managed with intravenous infusions
B, Marasini +3 more
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Hereditary angioedema and pregnancy
The Journal of Maternal-Fetal & Neonatal Medicine, 2007Hereditary Angioedema is a rare but potentially life threatening condition. It is important that Obstetricians are aware of this condition as it affects women in the reproductive years and thus its recognition and proper management in pregnancy is crucial.
S, Duvvur, F, Khan, K, Powell
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An update on hereditary angioedema
Current Opinion in Pediatrics, 2012To review and update the management and understanding of hereditary angioedema (HAE), while integrating insights into pediatric subtleties that exist in practice.Major advances have recently been made in HAE treatment. Ecallantide (a kallikrein inhibitor approved for use in the United States in December 2009) and icatibant (a selective bradykinin B2 ...
Derek, Hsu, Marcus, Shaker
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Management of hereditary angioedema
Nursing Standard, 2013Hereditary angioedema is characterised by unpredictable, painful and potentially life-threatening oedema. Recently, some C1 inhibitors have been approved for self-administration and/or routine prevention, enabling patients to be proactive in managing their disease and reducing the burden of illness.
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The management of hereditary angioedema
La Ricerca in Clinica e in Laboratorio, 1983Our experience in managing 120 cases of hereditary angioedema is reported. Forty-two severe episodes of mucous or subcutaneous edema were successfully managed using CI-INH concentrate. A prophylactic treatment was done with two classes of drugs: antifibrinolytic agents (tranexamic acid) and 17α-alkylated androgen derivatives.
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