Results 41 to 50 of about 144,374 (198)

Hereditary angioedema type II and dental extraction: case report and literature review

Journal of Oral Medicine and Oral Surgery, 2020
Introduction: The hereditary angioedema of type II (HAE type II) is a disease which, in the case of invasive acts such as dental extractions, can trigger potentially fatal laryngeal edema.
Aroufi Wafa, Pavageau Claire, Sturque Julie, Zlowodzki Aude-Sophie, Georgescou Gabriela, Denis Frédéric   +5 more
doaj   +1 more source

Effectiveness of an Educational Program in Empowering Nursing Students' Knowledge Regarding Hereditary Angioedema [PDF]

Egyptian Journal of Health Care
Background: Hereditary Angioedema (HAE) is a rare genetic condition that can be life-threatening and profoundly affect the lives of those who are affected.
Amany Lotfy Ahmed, Nabila Salem Mohammed, Amany Abdelfattah Omran   +2 more
doaj   +1 more source

Hereditary Angioedema: Diagnosis, Clinical Implications, and Pathophysiology [PDF]

, 2023
Hereditary angioedema (HAE) is an autosomal dominant disorder caused by a mutation in the C1 esterase inhibitor gene. HAE affects 1/50,000 people worldwide. Three main types of HAE exist: type I, type II, and type III.
Malone, Kevin, Ahmadzadeh, Shahab, Roberts, Logan, Vemulapalli, Harshitha, Cornett, Elyse M., Issa, Peter P., Kaye, Alan D., Norwood, Haley, Sinnathamby, Evan S., Shekoohi, Sahar   +9 more
core   +1 more source

Elevated level of circulating VEGF in Chinese patients with hereditary angioedema and its correlation with disease status

Orphanet Journal of Rare Diseases
Background Hereditary angioedema (HAE) is a rare inherited disease characterized by recurrent, potentially life-threatening angioedema. The vascular endothelium dysfunction is reported to play a role in angioedema episodes.
Ruoyu Ji, Yijing Xu, Yuxiang Zhi
doaj   +1 more source

Real‐World Safety and Effectiveness of Icatibant in Patients With Hereditary Angioedema (HAE): Post‐Marketing Surveillance in Japan

The Journal of Dermatology, EarlyView.
ABSTRACT Hereditary angioedema (HAE) is a rare, autosomal dominant, life‐threatening disease characterized by recurrent attacks of swelling of the face, upper airway, gastrointestinal tract, limbs, and/or genitalia. Genetic mutations of the SERPING1 gene encoding the C1‐inhibitor (C1‐INH) plasma protein are associated with HAE‐C1INH.
Kumiko Hosono, Miyako Hoshino
wiley   +1 more source

Gene Editing for Haemophilia—The Next Frontier

Haemophilia, EarlyView.
ABSTRACT The recently approved haemophilia A and B gene therapies via adeno‐associated virus (AAV) showed a promising therapeutic response after a single injection, but there are still limitations, including the potential loss of transgene expression and restriction in adults.
Mirko Pinotti, Gregory A. Newby, Sundar Selvaraj, Steven W. Pipe   +3 more
wiley   +1 more source

Smart Design: Integrating Artificial Intelligence and Gene Editing for Advanced mRNA Therapeutics

MedComm – Biomaterials and Applications, Volume 5, Issue 3, September 2026.
The challenges of mRNA therapy and the application of artificial intelligence and gene editing in the field of mRNA drugs. ABSTRACT Artificial intelligence (AI) and gene editing are increasingly being applied to the design and evaluation of mRNA therapeutics.
Haixing Shi, Shengbin Liu, Danni Dai, Shanhui Jiang, Tingchen Tian, Zhenyi Niu, Zhongzheng Xiang, Chaoyu Zou, Fang Liu, Xue Tang, Xin Jiang, Xiangrong Song   +11 more
wiley   +1 more source

A Potentially Fatal Outcome of Oral Contraceptive Therapy: Estrogen-Triggered Hereditary Angioedema in an Adolescent

JCRPE, 2023
Hereditary angioedema (HAE) is characterized by recurrent angioedema attacks with no urticaria. This disease has a high mortality due to asphyxia. Level of complement component 4 (C4), C1 esterase inhibitor (C1-INH) level and function, and genetic ...
Demet Demirkol, Gül Yeşiltepe Mutlu, Esra Birben, Özge Soyer, Özlem Yılmaz, Cansın Saçkesen   +5 more
doaj   +1 more source

Airway Intervention in Paediatric Angioedema: A National Analysis of Clinical Predictors and Outcomes

Clinical Otolaryngology, Volume 51, Issue 5, Page 729-735, September 2026.
ABSTRACT Objective To characterize paediatric hospitalizations for angioedema and identify the prevalence and outcomes of airway interventions using a large national database. Methods We performed a cross‐sectional analysis of the Kids' Inpatient Database (2003–2019), including paediatric patients (0–20 years) hospitalized with angioedema identified by
Saharsh Talwar, Aryan Mahajan, Gaurav N. Pathak, Babar K. Rao, Rachel Kaye   +4 more
wiley   +1 more source

Are pediatricians familiar with hereditary angioedema?

World Allergy Organization Journal, 2023
Background: Hereditary angioedema (HAE) is an autosomal dominant disease characterized by recurrent episodes of subcutaneous or mucosal edema caused by excess bradykinin.
Herberto José Chong-Neto, M.D., Ph.D, Bárbara Padilha Aroni, M.D, Eli Mansour, M.D, Ph.D, Eliana Toledo, M.D., Ph.D, Faradiba Sarquis Serpa, M.D., Ph.D, Luisa Karla Arruda, M.D, Ph.D, Pedro Giavina-Bianchi, M.D., Ph.D, Solange Oliveira Rodrigues Valle, M.D., Ph.D, Caroline Guth de Freitas Batista de Moraes, M.T., MSc, Tatielly Kruk, M.T., MSc, Débora Carla Chong-Silva, MD, PhD, Dirceu Solé, M.D., Ph.D, Luciana Rodrigues Silva, M.D., Ph.D, Anete S. Grumach, M.D., Ph.D, Nelson Augusto Rosário Filho, M.D., Ph.D, Régis de Albuquerque Campos, M.D., Ph.D   +15 more
doaj   +1 more source