Results 121 to 130 of about 10,179 (209)
Evaluation of Serum Zonulin Levels and Intestinal Permeability in Hidradenitis Suppurativa Patients
ABSTRACT Background Hidradenitis Suppurativa (HS) is a chronic inflammatory skin disease. Zonulin is a signaling protein secreted by enterocytes that regulates the function of tight junction complexes and intestinal permeability. The levels of zonulin increase in the blood with the disruption of the intestinal barrier and it is used as a biomarker ...
Elif Çetinkaya +7 more
wiley +1 more source
Functional studies on autoinflammatory diseases, focusing in particular on Blau syndrome [PDF]
BACKGROUND The autoinflammatory diseases are disorders characterized by recurrent inflammatory episodes in charge of different organs. There is no apparent involvement of autoantibodies nor of antigen-specific T lymphocytes, but dysregulation of the ...
Galozzi, Paola
core
ABSTRACT Background ReCell autologous cell transplantation demonstrates efficacy in vitiligo repigmentation. Traditional Chinese medicine, such as Quchong Banjiuju Pill, may synergize with ReCell to enhance results, though combined protocols remain underexplored. Aims This study evaluated the efficacy and safety of ReCell combined with Quchong Banjiuju
Qiao Chen +8 more
wiley +1 more source
Immune endotypes in tuberculosis: Keys to decoding disease complexity
Abstract Tuberculosis (TB) remains a major global health challenge, with multi‐drug antibiotic regimens as the current standard of care. While effective at killing Mycobacterium tuberculosis, these treatments do not resolve persistent inflammation, prevent lung damage, or reverse immune dysregulation that contribute to poor outcomes and disease ...
Shamila D. Alipoor +4 more
wiley +1 more source
PECU: A multicenter study on pediatric patients with cold‐induced urticaria
Abstract Background Cold‐induced urticaria (ColdU) is a rare chronic inducible urticaria that can cause systemic reactions, including cold‐induced anaphylaxis (ColdA), but pediatric data are limited. The aim of this study was to evaluate the clinical characteristics, comorbidities, management approaches, risk of anaphylaxis, and long‐term course of ...
Betul Gemici Karaaslan +59 more
wiley +1 more source
This graphical abstract illustrates the conceptual framework linking rare and common diseases in pediatric allergy and immunology through precision medicine. On the left, rare conditions such as inborn errors of immunity and primary atopic disorders represent well‐defined monogenic models that reveal fundamental mechanisms of immune dysregulation.
Riccardo Castagnoli +26 more
wiley +1 more source
Background Amyloidosis is a rare heterogeneous disease in which proteins undergo conformational change and are deposited as amyloid fibrils. Hereditary amyloidosis (HA) is caused by deposition of genetically variant proteins, whereas AA amyloidosis ...
Rowczenio, DM
core
Autoinflammatory syndromes behind the scenes of recurrent fevers in children.
Many children experience recurrent fevers with no easily identifiable source and only a careful follow-up helps in the early identification of other presenting symptoms of other defined conditions which require medical intervention.
Rigante, Donato
core
Description of a Large Family with Periodic Fever Carrying a Variant in RXFP1 Gene: A Possible Novel Modulator of Inflammation in Autoinflammatory Diseases. [PDF]
Buttarelli M +5 more
europepmc +1 more source
Case Report: Familial Cold Autoinflammatory Syndrome With Double Variant in <i>NLRP12</i> and <i>SETD1A</i>. [PDF]
Ruíz-Santana JE +6 more
europepmc +1 more source

