Results 121 to 130 of about 2,214,075 (211)

Clinical Conditions that Masquerade as Urticaria

European Medical Journal, 2019
Chronic urticaria is one of the most commonly diagnosed dermatoses. Following diagnosis, correct identification and proper treatment significantly reduces disease activity, thereby improving the patient’s quality of life.
Nofar Kimchi,, Jonathan A. Bernstein
doaj  

The Transcription Factor EGR2 Plays a Central Role in the Expansion and Function of TCRαβ + CD4 − CD8 − Double Negative T Cells in lpr Lupus Mice

Immunology, Volume 179, Issue 2, Page 224-235, October 2026.
The highly expanded TCRβ+ DNT cells in autoimmune‐prone B6/lpr mice are phenotypically and functionally different from the TCRβ+DNT cells of normal B6 mice. Conditional Egr2 deletion in B6/lpr mice not only reduces TCRβ+ DNT cell numbers but also tends to correct the phenotypic and functional abnormalities of DNT cells in B6/lpr mice. In addition, Egr2
Rujuan Dai, Zhuang Wang, Bettina Heid, Christopher M. Reilly, S. Ansar Ahmed   +4 more
wiley   +1 more source

Clinical management of clonal hematopoiesis

Cancer, Volume 132, Issue 18, 15 September 2026.
ABSTRACT Clonal hematopoiesis, particularly clonal hematopoiesis of indeterminate potential and clonal cytopenia of undetermined significance, is an age‐related premalignant condition characterized by the expansion of hematopoietic clones carrying somatic mutations.
Kelly S. Chien, Guillermo Garcia‐Manero   +1 more
wiley   +1 more source

An update on autoinflammatory diseases

, 2014
Autoinflammatory diseases are a group of clinical conditions other than autoimmune diseases, characterized by recurrent inflammatory episodes. From a pathogenetic point of view they are determined by a dysregulation of innate immunity, without ...
DE MARTINIS, MASSIMO MARIA MARCELLO, Ciccarelli F, GINALDI, Lia   +2 more
core  

Mevalonate kinase deficiency in a familial Mediterranean fever endemic region: a single-center experience

The Turkish Journal of Pediatrics
Background. We aimed to document childhood onset mevalonate kinase deficiency (MKD) and to explore treatment responses and diagnostic challenges in regions endemic to familial Mediterranean fever (FMF). Methods.
Elif Kılıç Könte, Ece Aslan, Nergis Akay, Ümit Gül, Esma Aslan, Aybüke Günalp, Fatih Haşlak, Mehmet Yıldız, Amra Adrovic, Sezgin Şahin, Kenan Barut, Özgür Kasapçopur   +11 more
doaj   +1 more source

Autoinflammatory disorders in Children [PDF]

, 2016
Autoinflammatory diseases arise when the control of innate inflammatory responses fails. These disorders are characterized by seemingly unprovoked or disproportionate inflammation, insufficiently explained by infection or autoimmunity.
Frenkel, J, Legger, G. Elizabeth
core  

Autoinflammatory syndromes

, 2006
The autoinflammatory disorders are a new and expanding classification of inflammatory diseases characterized by recurrent episodes of systemic inflammation in the absence of pathogens, autoantibodies or antigen specific T cells.
GALEAZZI, M., HOFFMAN, H. M., DORIA, A., PUNZI, L., GASBARRINI, G., MANNA, R., GHIRARDELLO, A., SEBASTIANI, G. D., PODSWIADEK, M., GRANDEMANGE, S., TOUITOU, I.   +10 more
core   +1 more source

Dysfunctional immunoproteasomes in autoinflammatory diseases [PDF]

, 2016
Recent progress in DNA sequencing technology has made it possible to identify specific genetic mutations in familial disorders. For example, autoinflammatory syndromes are caused by mutations in gene coding for immunoproteasomes.
有持, 秀喜, Yasutomo, Koji, 60214/profile-ja.html, 50454757, 30333511, 60033/profile-ja.html, キタムラ, アキコ, ササキ, ユキ, Arimochi, Hideki, Sasaki, Yuki, 321, Kitamura, Akiko, 1521, 30311822, 676, 北村, 明子, 10448318, アリモチ, ヒデキ, 佐々木, 由紀, 1616, 273670/profile-ja.html, 安友, 康二, ヤストモ, コウジ   +22 more
core  

Blocking interleukin-1beta in acute and chronic autoinflammatory diseases.

, 2010
Item does not contain fulltextAn expanding spectrum of acute and chronic inflammatory diseases is considered 'autoinflammatory' diseases. This review considers autoinflammatory diseases as being distinct from 'autoimmune' diseases.
Dinarello, C.A., C. A. Dinarello
core   +1 more source

Hereditary Autoinflammatory Diseases; Diagnosis and Management

Nihon Naika Gakkai Zasshi, 2014
Kiyoshi Migita, Atsushi Kawakami, Katsumi Eguchi   +2 more
openaire   +2 more sources