Results 71 to 80 of about 15,219 (276)

Chronic hepatitis B complicated with secondary hemochromatosis was cured clinically: A case report

Open Medicine, 2023
Chronic hepatitis B (CHB) often causes iron overload in the liver but rarely causes severe secondary hemochromatosis (SH). A 48-year-old man was infected with CHB via vertical transmission. For 21 years, nonstandard treatment with second-line hepatitis B
Ye Yun, Xie Jing, Wang Lina, He Cong, Tan Youwen   +4 more
doaj   +1 more source

Association of hemochromatosis with infectious diseases: expanding spectrum [PDF]

, 2007
SummaryWithholding iron from potential pathogens is a host defense strategy. There is evidence that iron overload per se compromises the ability of phagocytes to kill microorganisms.
Fisher, Melanie A., Khakoo, Rashida A., Khan, Fida A.   +2 more
core   +1 more source

Clinical decision instruments for predicting mortality in patients with cirrhosis seeking emergency department care

Academic Emergency Medicine, EarlyView.
Abstract Objective Clinical decision instruments (CDIs) could be useful to aid risk stratification and disposition of emergency department (ED) patients with cirrhosis. Our primary objective was to derive and internally validate a novel Cirrhosis Risk Instrument for Stratifying Post‐Emergency department mortality (CRISPE) for the outcomes of 14‐ and 30‐
Swetha Parvataneni, Michelle Haugh, Yara Sarkis, Brittany Baker, Lauren D. Nephew, Marwan S. Ghabril, Raj Vuppalanchi, Eric S. Orman, Naga P. Chalasani, Archita P. Desai, Nicholas Eric Harrison   +10 more
wiley   +1 more source

Non-HFE hemochromatosis

Revista Brasileira de Hematologia e Hemoterapia, 2012
Hereditary hemochromatosis (HH) is an autosomal recessive disorder classically related to HFE mutations. However, since 1996, it is known that HFE mutations explain about 80% of HH cases, with the remaining around 20% denominated non-HFE hemochromatosis.
Paulo Caleb Júnior de Lima Santos, Carla Luana Dinardo, Rodolfo Delfini Cançado, Isolmar Tadeu Schettert, José Eduardo Krieger, Alexandre Costa Pereira   +5 more
doaj   +1 more source

Incorporating familial risk, lifestyle factors, and pharmacogenomic insights into personalized noncommunicable disease (NCD) reports for healthcare funder beneficiaries participating in the Open Genome Project

Annals of Human Genetics, EarlyView.
Abstract Introduction An ethics‐guided decision‐making framework was developed for applying pathology‐supported genetic testing, a multifaceted pharmacodiagnostic approach that translates population risk stratification into clinical utility. We introduce this service, supported by the Open Genome Project, which aligns with the beneficence principle in ...
Manie De Klerk, Nicole Van Der Merwe, Johny Erasmus, Lindiwe Whati, Kelebogile E. Moremi, Daniel W. Olivier, Maritha J. Kotze   +6 more
wiley   +1 more source

Molecular pathogenesis of hereditary hemochromatosis.

Histology and histopathology, 2016
Hereditary hemochromatosis (HH) is an inherited iron overload disorder characterized by normal iron-driven erythropoiesis and abnormal iron metabolism, leading to excess iron deposited in parenchymal cells of liver, heart, and endocrine glands. Iron hormone, hepcidin, plays a critical role in iron homeostasis through interaction with ferroportin (FPN),
Jingqi Liu, Chunmeng Jiang, Lang Lang, Liang Qiao, Chunwen Pu, Mohamud Abukar Haji Abdullahi   +5 more
openaire   +4 more sources

Infectious Mononucleosis Causing Acute Liver Failure and Hemolytic Anemia in a Patient with Underlying Hereditary Hemochromatosis

Case Reports in Oncology, 2020
Infectious mononucleosis is a largely benign disease process that occurs secondary to infection with the Epstein-Barr virus. However, it can also present with more serious complications, including auto-immune hemolytic anemia and acute liver failure ...
Mark Forsberg, Mark Galan, Joshua Kra
doaj   +1 more source

A Successful Living Donor Liver Transplantation Using Hepatic Iron Deposition Graft Suspected by Magnetic Resonance Imaging

Case Reports in Transplantation, 2023
Recently, magnetic resonance imaging (MRI) has been developed as a widely available and noninvasive method for detecting and evaluating hepatic iron overload.
Nobuhiko Kurata, Masato Shizuku, Kanta Jobara, Yoji Ishizu, Masatoshi Ishigami, Yasuhiro Ogura   +5 more
doaj   +1 more source

Strongly quasi-hereditary algebras and rejective subcategories [PDF]

Nagoya Math. J. 237 (2020) 10-38, 2017
Ringel's right-strongly quasi-hereditary algebras are a distinguished class of quasi-hereditary algebras of Cline-Parshall-Scott. We give characterizations of these algebras in terms of heredity chains and right rejective subcategories. We prove that any artin algebra of global dimension at most two is right-strongly quasi-hereditary.
arxiv   +1 more source

The role of iron in normal and impaired testicular function

Andrology, EarlyView.
Abstract Iron plays a critical role in testicular physiology, impacting spermatogenesis, testosterone production, and overall testicular function. Iron homeostasis is maintained through systemic and cellular regulatory mechanisms, including hepcidin‐mediated systemic iron control and the iron‐responsive element/iron regulatory protein (IRE/IRP) system ...
Aileen Harrer, Esther G. Meyron‐Holtz, Andreas Meinhardt   +2 more
wiley   +1 more source