Results 111 to 120 of about 16,165 (220)

Hereditary Nonpolyposis Colorectal Carcinoma: Cancer Family Syndrome

Annals of Medicine, 1989
During the past 20 years details of hundreds of families with aggregation of nonpolyposis colorectal carcinoma (CRC) have been published. High frequency of CRC and some other adenocarcinomas with early age of onset, with common multiplicity and with dominant mode of genetic transmission are characteristic for this inherited disorder originally called ...
openaire   +2 more sources

GENETIC COUNSELOR UTILIZATION AND INTERPRETATION OF SOMATIC TUMOR TESTING IN EVALUATION FOR LYNCH SYNDROME [PDF]

, 2019
Lynch syndrome (LS) is a hereditary cancer predisposition syndrome characterized by increased risk for colorectal and uterine cancers. Individuals with pathogenic variants in the mismatch repair (MMR) genes (MLH1, MSH2/EPCAM, MSH6, PMS2) are diagnosed ...
Williams, Danielle
core   +1 more source

Hereditary nonpolyposis colorectal cancer and familial colorectal cancer in Central part of Iran, Isfahan

Journal of Research in Medical Sciences, 2012
Background: There is a lack of data on familial aggregation of colorectal cancer (CRC) in Iran. We aimed to deter-mine the frequency of hereditary nonpolyposis colorectal cancer (HNPCC) and familial colorectal cancer (FCC) and to determine the frequency ...
Amin Nemati, Zahra Kazemi Rahmatabadi, Alimohammad Fatemi, Mohammad Hassan Emami   +3 more
doaj  

Rare single‐nucleotide variants of MLH1 and MSH2 genes in patients with Lynch syndrome

Cancer Reports
Background Approximately 5% of colorectal cancers (CRCs) are hereditary. Lynch syndrome (LS), also known as hereditary nonpolyposis colorectal cancer (HNPCC), is the most common form of recognized hereditary CRC.
Seyed Mohsen Mirabdolhosseini, Mohammad Yaghoob Taleghani, Leili Rejali, Hossein Sadeghi, Nayeralsadat Fatemi, Mehdi Tavallaei, Amin Famil Meyari, Narges Saeidi, Pardis Ketabi Moghadam, Amir Sadeghi, Hamid Asadzadeh Aghdaei, Mohammad Reza Zali, Ehsan Nazemalhosseini Mojarad   +12 more
doaj   +1 more source

Molecular screening for hereditary nonpolyposis colorectal cancer in Bulgaria

Open Medicine, 2006
Kadiyska Tanya, Goranova Teodora, Dineva Ganka, Nedin Dimitar, Alexandrova Alexandrina, Gegova Antonina, Kaneva Radka, Damyanov Damyan, Kremensky Ivo, Mitev Vanio   +9 more
doaj   +1 more source

Family history is neglected in the work-up of patients with colorectal cancer: a quality assessment using cancer registry data [PDF]

, 2007
D. A. van Dijk, M. J. Oostindiër, W. M. Kloosterman-Boele, P. Krijnen, H. F. A. Vasen, HT Lynch, P Peltomaki, HF Vasen, WH Vos tot Nederveen Cappel de, WH Vos tot Nederveen Cappel de, HJ Jarvinen, AE Jong De, W Kievit, FH Menko, MA Rodriguez-Bigas, A Umar, HF Vasen   +16 more
core   +1 more source

Muir-Torre Syndrome, a Rare Phenotype of Hereditary Nonpolyposis Colorectal Cancer With Cutaneous Manifestations. [PDF]

ACG Case Rep J, 2019
Rubay D, Ohanisian L, Bank MP, Kaur N, Genuit T, Ross A.   +5 more
europepmc   +1 more source

Hereditary Nonpolyposis Colorectal Cancer [PDF]

, 2020
openaire   +1 more source

MLH1-rheMac hereditary nonpolyposis colorectal cancer syndrome in rhesus macaques. [PDF]

Proc Natl Acad Sci U S A, 2018
Brammer DW, Gillespie PJ, Tian M, Young D, Raveendran M, Williams LE, Gagea M, Benavides FJ, Perez CJ, Broaddus RR, Bernacky BJ, Barnhart KF, Alauddin MM, Bhutani MS, Gibbs RA, Sidman RL, Pasqualini R, Arap W, Rogers J, Abee CR, Gelovani JG.   +20 more
europepmc   +1 more source

Hereditary Nonpolyposis Colorectal Cancer and Cancer Syndromes: Recent Basic and Clinical Discoveries. [PDF]

J Oncol, 2018
Chen E, Xu X, Liu T.
europepmc   +1 more source