Results 101 to 110 of about 10,784 (208)

The annotation results for the top ten novel CNVs from microsatellite stable hereditary nonpolyposis colorectal cancer samples using the CNVannotator web server.

, 2013
The annotation results for the top ten novel CNVs from microsatellite stable hereditary nonpolyposis colorectal cancer samples using the CNVannotator web server.
Zhongming Zhao (40519), Min Zhao (66793)
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Deciding the operation type according to mismatch repair status among hereditary nonpolyposis colorectal cancer patients: should a tailored approach be applied, or does one size fit all? [PDF]

Hered Cancer Clin Pract, 2021
Liao CK, Lin YC, Hsu YJ, Chern YJ, You JF, Chiang JM.   +5 more
europepmc   +1 more source

Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer

, 1993
Recent studies have shown that a locus responsible for hereditary nonpolyposis colorectal cancer (HNPCC) is on chromosome 2p and that tumors developing in these patients contain alterations in microsatellite sequences (RER + phenotype).
Papadopoulos, N, Todd, S, Guan, XY, Fournier, REK, NystromLahti, M, Meltzer, PS, Nicolaides, NC, Cerosaletti, KM, Jen, J, Sistonen, P, Leach, FS, Kao, FT, Aaltonen, LA, Peltomaki, P, Yu, JW, Chen, DJ, Liu, B, Parsons, R, Zhang, J   +18 more
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MSH6 mutations are frequent in hereditary nonpolyposis colorectal cancer families with normal pMSH6 expression as detected by immunohistochemistry

, 2012
Hereditary nonpolyposis colorectal cancer (HNPCC) is an autosomal dominant condition accounting for 2% to 4% of all colorectal cancer cases worldwide. Families with germ line mutations in 1 of 6 mismatch repair genes are known as Lynch syndrome families.
Okkels, Henrik, Krarup, Henrik Bygum, Vyberg, Mogens, Bernstein, Inge Thomsen, Lindebjerg, Jan, Lindorff-Larsen, Karen, Bernstein, Inge, Holck, Susanne, Klarskov, Louise, Klarskov, Louise Laurberg, Thorlasius-Ussing, Ole, Sunde, Lone   +11 more
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Suspected hereditary nonpolyposis colorectal cancer - International Collaborative Group on Hereditary Non-Polyposis Colorectal Cancer (ICG-HNPCC) criteria and results of genetic diagnosis

, 1999
PURPOSE: The aim of this study was to determine the frequency of mutations in the mismatch repair genes in families suspected of having hereditary nonpolyposis colorectal cancer.
Peltomaki P, Park JG, Miyaki M, Wijnen JT, Park KJ, Rodriguez Bigas MA, Lynch HT, Vasen HFA, PONZ DE LEON, Maurizio, Lubinski J, Bisgaard ML, Beck NE, Baba S   +12 more
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Genetic profiles of hereditary nonpolyposis colorectal cancer.

, 2011
469 Background: With the aim to identify genetic markers of hereditary nonpolyposis colorectal cancer (HNPCC), we applied tiling BAC array-based comparative genomic hybridization (aCGH) to 46 HNPCC-associated colorectal cancer. Methods: 32 k iling BAC
C. Therklidsen, G. Jonsson, M. Nilbert, I. Bernstein   +3 more
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Lynch syndrome (hereditary nonpolyposis colorectal cancer) diagnostics

, 2007
Background Preventive programs for individuals who have high lifetime risks of colorectal cancer may reduce disease morbidity and mortality. Thus, it is important to identify the factors that are associated with hereditary colorectal cancer and to ...
Halvarsson, Britta, Nilbert, Mef, Kolodner, Richard D., Lindblom, Annika, Vogelstein, Bert, Vandrovcova, Jana, Kinzler, Kenneth W., Papadopoulos, Nickolas, Clendenning, Mark, Frebourg, Thierry, Halvarsson, Britta,, Peltomaki, Paivi, Liu, Tao, Lund University., Robinson, Kristina Lagerstedt, Nilbert, Mef,   +15 more
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Refining Risk Estimates in Hereditary Nonpolyposis Colorectal Cancer: Are We There Yet? [PDF]

JNCI Cancer Spectr, 2020
Lynch PM, Pande M.
europepmc   +1 more source

Cancer Risk Analysis in Families with Hereditary Nonpolyposis Colorectal Cancer

, 2006
Colorectal cancer (CRC) is one of the most common fatal cancers in developed countries and represents a significant public-health issue. About 3%-5% of patients with CRC have hereditary nonpolyposis colorectal cancer (HNPCC).
Banfield Younghusband, H, Jancovic, Peter, Kokuer, M, Green, RC, Naguib, R N   +4 more
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Familial mutations in PMS2 can cause autosomal dominant hereditary nonpolyposis colorectal cancer

, 2005
Background & Aims: Hereditary nonpolyposis colorectal cancer (HNPCC) is an autosomal dominant disorder caused by familial mutations in some of the genes responsible for DNA mismatch repair. Mutations in the MLH1, MSH2, and MSH6 genes have been documented
Worthley, D., Suthers, G., Ruszkiewicz, A., Barker, M., Bennett, G., Walsh, M., Phillips, K.   +6 more
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