Results 91 to 100 of about 16,258 (219)

SPECIAL FEATURES OF CARCINOGENESIS OF COLON ADENOCARCINOMA

Сибирский онкологический журнал, 2016
Colorectal cancer is one of the most common malignancies and the leading cause of cancer-related death. There are 4 basic colon carcinogenic steps: malignant transformation of adenoma into carcinoma; HNPCC (hereditary nonpolyposis colon cancer); cancer ...
G. A. Raskin, S. V. Petrov, R. V. Orlova
doaj  

Reduced expression of alanyl aminopeptidase is a robust biomarker of non-familial adenomatous polyposis and non-hereditary nonpolyposis colorectal cancer syndrome early-onset colorectal cancer. [PDF]

Cancer Med, 2023
Ha YJ, Shin YJ, Tak KH, Park JL, Kim JH, Lee JL, Yoon YS, Kim CW, Kim SY, Kim JC.   +9 more
europepmc   +1 more source

Numbers of mutations to different types of colorectal cancer

BMC Cancer, 2005
Background The numbers of oncogenic mutations required for transformation are uncertain but may be inferred from how cancer frequencies increase with aging. Cancers requiring more mutations will tend to appear later in life.
Tavaré Simon, Aaltonen Lauri A, Järvinen Heikki J, Mecklin Jukka-Pekka, Calabrese Peter, Shibata Darryl   +5 more
doaj   +1 more source

Prediction of hereditary nonpolyposis colorectal cancer using mRNA MSH2 quantitative and the correlation with nonmodifiable factor. [PDF]

World J Gastrointest Pathophysiol, 2021
Tedjasaputra TR, Hatta M, Massi MN, Natzir R, Bukhari A, Masadah R, Parewangi ML, Prihantono P, Nariswati R, Tedjasaputra V.   +9 more
europepmc   +1 more source

DNA content analysis of colorectal cancer defines a distinct ‘microsatellite and chromosome stable’ group but does not predict response to radiotherapy [PDF]

, 2014
Colorectal cancers (CRC) are thought to have genetic instability in the form of either microsatellite instability (MSI) or chromosomal instability (CIN).
Abdel-Rahman, Araujo, Armitage, Baba, Bertagnolli, Curtis, Dhadda, Dhadda, Fadhil, Fadhil, Fearon, Fisher, Flyger, Fodde, Frei, Georgiades, Goh, Hadjihannas, Hawkins, Hedley, Heimann, Hutchins, Ilyas, Ingh, Jass, Karran, Kouri, Levitt, Lothe, Michelassi, Ormerod, Palles, Pino, Pritchard, Quirke, Rajagopalan, Ribic, Sieber, Silver, Suarez, Tang, The Cancer Genome Atlas Network, Thibodeau, Vecchio, Williams   +44 more
core   +2 more sources

Hereditary Nonpolyposis Colorectal Cancer in Association with Crohn's Disease and Lynch Syndrome: The Importance of a Strict Endoscopic Surveillance. [PDF]

Case Rep Gastroenterol, 2022
Hahn GD, Wetwittayakhlang P, Afif W, Bessissow T, Lakatos PL.   +4 more
europepmc   +1 more source

Current clinical criteria for Lynch syndrome are not sensitive enough to identify MSH6 mutation carriers [PDF]

, 2010
Background: Reported prevalence, penetrance and expression of deleterious mutations in the mismatch repair (MMR) genes, MLH1, MSH2, MSH6 and PMS2, may reflect differences in the clinical criteria used to select families for DNA testing.
Sjursen, Wenche, Haukanes, Bjørn Ivar, Grindedal, Eli Marie, Aarset, Harald, Stormorken, Astrid Tenden, Engebretsen, Lars Fredrik, Jonsrud, Christoffer, Bjørnevoll, Inga, Andresen, Per Arne, Ariansen, Sarah, Lavik, Liss Anne S., Gilde, Bodil, Bowitz-Lothe, Inger Marie, Mæhle, Lovise, Møller, Pål   +14 more
core   +1 more source

Survival of hereditary non-polyposis colorectal cancer patients compared with sporadic colorectal cancer patients

Journal of Experimental & Clinical Cancer Research, 2008
Background Patients with hereditary non-poliposys colorectal cancer (HNPCC) have better prognosis than sporadic colorectal cancer (CRC). Aim of our retrospective study was to compare the overall survival between sporadic CRC and HNPCC patients.
Mete Lupe, Mottolese Marcella, Giannarelli Diana, Palmirotta Raffaele, Cosimelli Maurizio, Assisi Daniela, Stigliano Vittoria, Mancini Raffaello, Casale Vincenzo   +8 more
doaj   +1 more source

Molecular genetic approach for screening of hereditary non-polyposis colorectal cancer

Zdravniški Vestnik, 2005
Background: The main goal of knowledge concerning human diseases is to transfer as much as possible useful information into clinical applications.
Metka Ravnik-Glavač
doaj  

Investigating of microsatellites instability in patients with hereditary non-polyposis colorectal cancer in Isfahan

Advanced Biomedical Research, 2014
Background: Microsatellites or simple sequence repeats are repeating sequences of deoxyribonucleic acid (DNA). Mutation in mismatch repair (MMR) genes can cause microsatellites instability (MSI) in some tumors.
Vida Homayouni, Mansour Salehi, Mohammad Kazemi   +2 more
doaj   +1 more source