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Dominantly Inherited Hereditary Nonpolyposis Colorectal Cancer Not Caused by MMR Genes. [PDF]
J Clin Med, 2020 In the past two decades, multiple studies have been undertaken to elucidate the genetic cause of the predisposition to mismatch repair (MMR)-proficient nonpolyposis colorectal cancer (CRC). Here, we present the proposed candidate genes according to their
Terradas M, Capellá G, Valle L.
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Hereditary Nonpolyposis Colorectal Cancer [PDF]
Definitions, 2020 Telomerase activity can be detected in most human cancers. These findings are consistent with the telomere hypothesis, which predicts telomerase expression after a number of mitotic divisions to prevent the progressive and catastrophic loss oftelomeres ...
Zhihua Li +4 more
semanticscholar +2 more sources
Hereditary Nonpolyposis Colorectal Cancer and Cancer Syndromes: Recent Basic and Clinical Discoveries. [PDF]
J Oncol, 2018 Approximately one-third of individuals diagnosed with colorectal cancer have a family history of cancer, suggesting that CRCs may result from a heritable component.
Chen E, Xu X, Liu T.
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Updates in the field of hereditary nonpolyposis colorectal cancer [PDF]
Expert Review of Gastroenterology & Hepatology, 2020 Introduction Up to one third of colorectal cancers show familial clustering and 5% are hereditary single-gene disorders. Hereditary non-polyposis colorectal cancer comprises DNA mismatch repair-deficient and -proficient subsets, represented by Lynch ...
P. Peltomäki, A. Olkinuora, T. Nieminen
semanticscholar +3 more sources
Pancreaticoduodenectomy for locally advanced colon cancer in hereditary nonpolyposis colorectal cancer. [PDF]
World J Surg Oncol, 2016 BackgroundHereditary nonpolyposis colorectal cancer (HNPCC), or Lynch syndrome, accounts for 3 % of newly diagnosed cases of colorectal cancer. While a partial or subtotal colectomy is indicated for early stage disease, there is a paucity of data ...
Zhu R, Grisotti G, Salem RR, Khan SA.
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Hereditary nonpolyposis colorectal cancer (HNPCC)/Lynch syndrome. [PDF]
Dtsch Arztebl Int, 2013 Steinke V +5 more
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Endoscopic and Surgical Management of Hereditary Nonpolyposis Colorectal Cancer [PDF]
Clinics in Colon and Rectal Surgery, 2012 Paul E Wise, Rebeccah B Baucom
exaly +2 more sources
Hereditary nonpolyposis colorectal cancer (Lynch syndrome): An updated review
Cancer, 1996 T Smyrk, H T Lynch
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Hereditary nonpolyposis colorectal cancer
Annals of Oncology, 1997 Colorectal cancer is a leading cause of cancer related death in both Europe and the United States. Approximately 20% of cases occur in familial aggregations making this disorder the most frequent form of hereditary neoplasia [1]. Consequently, patients with colorectal cancer often present with a positive family history which may have significant ...
S, O'Reilly +3 more
openaire +4 more sources