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Hereditary Nonpolyposis Colon Cancer (Lynch Syndrome): An Emerging Public Health Concern [PDF]

open access: yesHealth Science Reports
Background Lynch syndrome, also known as hereditary nonpolyposis colorectal cancer (HNPCC), is an autosomal dominant disorder caused by germline mutations in DNA mismatch repair (MMR) genes that confer increased lifetime risks for colorectal, endometrial,
Md Mohiuddin
doaj   +3 more sources

Lung adenocarcinoma and colorectal cancer as double primary malignancies reveal lynch syndrome: a case report of germline MLH1 mutation with response to immunotherapy and familial aggregation [PDF]

open access: yesFrontiers in Immunology
Lynch syndrome (LS), also known as hereditary nonpolyposis colorectal cancer, is a genetic condition that increases the risk of developing colorectal cancer (CRC) and other cancers due to defective DNA mismatch repair (dMMR).
Menglei Wang   +10 more
doaj   +2 more sources

Hereditary Nonpolyposis Colorectal Cancer (HNPCC)/Lynch Syndrome: Surveillance and Diagnostic strategies

open access: diamondMajallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2021
Introduction: Hereditary nonpolyposis colorectal cancer (HNPCC, Lynch syndrome) is an autosomal dominant genetic disease. The disease is caused by a mutation in one of four genes of the DNA mismatch repair system and increases the risk for various ...
Mohammad Hassan Jokar   +2 more
doaj   +2 more sources

Algunos aspectos genéticos, moleculares y clínicos del cáncer colorrectal hereditario no polipoideo Some genetic, molecular and clinical aspects of nonpolyposis hereditary colorectal cancer

open access: greenRevista Cubana de Investigaciones Biomédicas, 2004
Se hizo una revisión con el objetivo de profundizar en el conocimiento del cáncer colorrectal hereditario no polipoideo; resaltando su evolución histórica, así como sus características genéticas, moleculares y clínicas que condicionan el manejo clínico ...
Silvia Gra Menéndez   +1 more
doaj   +1 more source

Prediction of hereditary nonpolyposis colorectal cancer using mRNA MSH2 quantitative and the correlation with nonmodifiable factor. [PDF]

open access: diamondWorld J Gastrointest Pathophysiol, 2021
Tedjasaputra TR   +9 more
europepmc   +2 more sources

MSH2 and APC mutated mouse models closely mimic the differences between hereditary nonpolyposis colorectal cancer and familial adenomatous polyposis [PDF]

open access: yesMicrobiota in Health and Disease, 2023
Introduction: Hereditary colorectal cancer occurs mainly in the setting of hereditary nonpolyposis colorectal cancer and familial adenomatous polyposis. VCMsh2LoxP/LoxP and ApcMin/+ are mouse models of these two human syndromes.
B. Oliveira Rocha   +5 more
doaj   +1 more source

Prevalence of hereditary nonpolyposis colorectal cancer in patients with colorectal cancer in Iran: a systematic review [PDF]

open access: yesReviews in Clinical Medicine, 2016
Introduction: Colorectal cancer (CRC) is the third leading cause of cancer deaths in the world, and hereditary factors and family history are responsible for the incidence and development of the disease in 20 to 30% of cases.
Abbas Esmaeilzadeh   +8 more
doaj   +1 more source

Syndrome in question [PDF]

open access: yesAnais Brasileiros de Dermatologia, 2015
Muir-Torre syndrome is a rare genodermatosis characterized by the occurrence of at least one sebaceous tumor associated with visceral neoplasia, but with no predisposing factors.
Catharina Maria Freire de Lucena Pousa   +4 more
doaj   +1 more source

Sebaceous Carcinoma of the Eyelid and Muir-Torre Syndrome

open access: yesActa Clinica Croatica, 2023
Muir-Torre syndrome is a rare form of hereditary nonpolyposis colorectal cancer syndrome; simplified, it is an association of at least one sebaceous skin tumor and at least one visceral malignancy.
Karla Ranđelović   +6 more
doaj   +1 more source

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