A Rare Case of Seminoma in an Elderly Patient With Suspected Lynch Syndrome [PDF]
Clinical Case ReportsLynch syndrome (LS), also known as hereditary nonpolyposis colorectal cancer, is caused by mutations in the mismatch repair genes and confers genetic predisposition to colorectal and other cancers.
Mostafa Kamandi +3 more
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Hereditary Nonpolyposis Colon Cancer (Lynch Syndrome): An Emerging Public Health Concern [PDF]
Health Science ReportsBackground Lynch syndrome, also known as hereditary nonpolyposis colorectal cancer (HNPCC), is an autosomal dominant disorder caused by germline mutations in DNA mismatch repair (MMR) genes that confer increased lifetime risks for colorectal, endometrial,
Md Mohiuddin
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Prevalence of hereditary nonpolyposis colorectal cancer in patients with colorectal cancer in Iran: a systematic review [PDF]
Reviews in Clinical Medicine, 2016 Introduction: Colorectal cancer (CRC) is the third leading cause of cancer deaths in the world, and hereditary factors and family history are responsible for the incidence and development of the disease in 20 to 30% of cases.
Abbas Esmaeilzadeh +8 more
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Lung adenocarcinoma and colorectal cancer as double primary malignancies reveal lynch syndrome: a case report of germline MLH1 mutation with response to immunotherapy and familial aggregation [PDF]
Frontiers in ImmunologyLynch syndrome (LS), also known as hereditary nonpolyposis colorectal cancer, is a genetic condition that increases the risk of developing colorectal cancer (CRC) and other cancers due to defective DNA mismatch repair (dMMR).
Menglei Wang +10 more
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MSH2 and APC mutated mouse models closely mimic the differences between hereditary nonpolyposis colorectal cancer and familial adenomatous polyposis [PDF]
Microbiota in Health and Disease, 2023 Introduction: Hereditary colorectal cancer occurs mainly in the setting of hereditary nonpolyposis colorectal cancer and familial adenomatous polyposis. VCMsh2LoxP/LoxP and ApcMin/+ are mouse models of these two human syndromes.
B. Oliveira Rocha +5 more
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Hereditary nonpolyposis colorectal cancer
Annals of Oncology, 1997 Colorectal cancer is a leading cause of cancer related death in both Europe and the United States. Approximately 20% of cases occur in familial aggregations making this disorder the most frequent form of hereditary neoplasia [1]. Consequently, patients with colorectal cancer often present with a positive family history which may have significant ...
S, O'Reilly +3 more
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Anais Brasileiros de Dermatologia, 2015 Muir-Torre syndrome is a rare genodermatosis characterized by the occurrence of at least one sebaceous tumor associated with visceral neoplasia, but with no predisposing factors.
Catharina Maria Freire de Lucena Pousa +4 more
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Sebaceous Carcinoma of the Eyelid and Muir-Torre Syndrome
Acta Clinica Croatica, 2023 Muir-Torre syndrome is a rare form of hereditary nonpolyposis colorectal cancer syndrome; simplified, it is an association of at least one sebaceous skin tumor and at least one visceral malignancy.
Karla Ranđelović +6 more
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Distinct gene expression signatures in lynch syndrome and familial colorectal cancer type x. [PDF]
PLoS ONE, 2013 Heredity is estimated to cause at least 20% of colorectal cancer. The hereditary nonpolyposis colorectal cancer subset is divided into Lynch syndrome and familial colorectal cancer type X (FCCTX) based on presence of mismatch repair (MMR) gene defects.We
Mev Dominguez-Valentin +6 more
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Clinics, 2005 Hereditary nonpolyposis colorectal cancer is an autosomal dominant condition caused by highly penetrant gene mutations. It is characterized by increased susceptibility for a specific group of cancer, mainly colorectal cancer. The syndrome originates from
Roberta Vasconcelos e Silva +4 more
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