Hereditary Nonpolyposis Colon Cancer (Lynch Syndrome): An Emerging Public Health Concern [PDF]
Background Lynch syndrome, also known as hereditary nonpolyposis colorectal cancer (HNPCC), is an autosomal dominant disorder caused by germline mutations in DNA mismatch repair (MMR) genes that confer increased lifetime risks for colorectal, endometrial,
Md Mohiuddin
doaj +3 more sources
Lung adenocarcinoma and colorectal cancer as double primary malignancies reveal lynch syndrome: a case report of germline MLH1 mutation with response to immunotherapy and familial aggregation [PDF]
Lynch syndrome (LS), also known as hereditary nonpolyposis colorectal cancer, is a genetic condition that increases the risk of developing colorectal cancer (CRC) and other cancers due to defective DNA mismatch repair (dMMR).
Menglei Wang +10 more
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Introduction: Hereditary nonpolyposis colorectal cancer (HNPCC, Lynch syndrome) is an autosomal dominant genetic disease. The disease is caused by a mutation in one of four genes of the DNA mismatch repair system and increases the risk for various ...
Mohammad Hassan Jokar +2 more
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Se hizo una revisión con el objetivo de profundizar en el conocimiento del cáncer colorrectal hereditario no polipoideo; resaltando su evolución histórica, así como sus características genéticas, moleculares y clínicas que condicionan el manejo clínico ...
Silvia Gra Menéndez +1 more
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Prediction of hereditary nonpolyposis colorectal cancer using mRNA MSH2 quantitative and the correlation with nonmodifiable factor. [PDF]
Tedjasaputra TR +9 more
europepmc +2 more sources
Characteristics of hereditary nonpolyposis colorectal cancer patients with double primary cancers in endometrium and colorectum. [PDF]
Shin SH +5 more
europepmc +3 more sources
MSH2 and APC mutated mouse models closely mimic the differences between hereditary nonpolyposis colorectal cancer and familial adenomatous polyposis [PDF]
Introduction: Hereditary colorectal cancer occurs mainly in the setting of hereditary nonpolyposis colorectal cancer and familial adenomatous polyposis. VCMsh2LoxP/LoxP and ApcMin/+ are mouse models of these two human syndromes.
B. Oliveira Rocha +5 more
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Prevalence of hereditary nonpolyposis colorectal cancer in patients with colorectal cancer in Iran: a systematic review [PDF]
Introduction: Colorectal cancer (CRC) is the third leading cause of cancer deaths in the world, and hereditary factors and family history are responsible for the incidence and development of the disease in 20 to 30% of cases.
Abbas Esmaeilzadeh +8 more
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Muir-Torre syndrome is a rare genodermatosis characterized by the occurrence of at least one sebaceous tumor associated with visceral neoplasia, but with no predisposing factors.
Catharina Maria Freire de Lucena Pousa +4 more
doaj +1 more source
Sebaceous Carcinoma of the Eyelid and Muir-Torre Syndrome
Muir-Torre syndrome is a rare form of hereditary nonpolyposis colorectal cancer syndrome; simplified, it is an association of at least one sebaceous skin tumor and at least one visceral malignancy.
Karla Ranđelović +6 more
doaj +1 more source

