Results 91 to 100 of about 10,129 (212)

Hereditary nonpolyposis colorectal cancer : factors contributing to adherence and non-adherence to surveillance for mutation carriers in rural areas of the Northern and Western Cape Brenda Julie Kruger.

open access: yes, 2005
Includes bibliographical references.The aim of this study was to explore possible factors that may affect non-adherence and adherence to surveillance guidelines for mutation positive individuals who are at high risk of developing CRC in the areas of the ...
Kruger, Brenda Julie
core  

Lynch syndrome (hereditary nonpolyposis colorectal cancer) diagnostics

open access: yes, 2007
Background Preventive programs for individuals who have high lifetime risks of colorectal cancer may reduce disease morbidity and mortality. Thus, it is important to identify the factors that are associated with hereditary colorectal cancer and to ...
Halvarsson, Britta   +15 more
core   +1 more source

Prevalence and characteristics of hereditary non-polyposis colorectal cancer (HNPCC) syndrome in immigrant Asian colorectal cancer patients

open access: yesBMC Cancer, 2017
Background The prevalence of Hereditary Non-Polyposis Colorectal Cancer (HNPCC) is 2 to 5% in the Caucasian population. HNPCC is caused by genomic mutations in DNA mismatch repair genes (MMR), namely MLH1, MSH2, MSH6, PMS2, and EPCAM.
Jasmine Lee   +10 more
doaj   +1 more source

Lack of MSH2 and MSH6 characterizes endometrial but not colon carcinomas in hereditary nonpolyposis colorectal cancer

open access: yes, 2001
Hereditary nonpolyposis colorectal cancer syndrome is associated with an inherited predisposition to primarily colorectal cancer (CRC) and endometrial cancer (EC); however, the biological basis of the organ involvement remains unknown.
Salovaara, R   +10 more
core   +1 more source

Longer telomeres are associated with cancer risk in MMR-proficient hereditary non-polyposis colorectal cancer.

open access: yesPLoS ONE, 2014
Aberrant telomere length measured in blood has been associated with increased risk of several cancer types. In the field of hereditary non-polyposis colorectal cancer (CRC), and more particularly in Lynch syndrome, caused by germline mutations in the ...
Nuria Seguí   +9 more
doaj   +1 more source

Screening for colorectal cancer

open access: yes
CA: A Cancer Journal for Clinicians, Volume 76, Issue 3, May/June 2026.
wiley   +1 more source

Deranged Wnt signaling is frequent in hereditary nonpolyposis colorectal cancer

open access: yes, 2011
The Wnt signaling pathway is frequently deranged in colorectal cancer and is a key target for future preventive and therapeutic approaches. Colorectal cancers associated with the hereditary nonpolyposis colorectal cancer (HNPCC) syndrome are ...
Bernstein, Inge   +4 more
core   +1 more source

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