Results 71 to 80 of about 10,129 (212)

Associations of the Colon Tissue Microbiome and Circulating Bile Acids With Colorectal Adenoma Among Average‐Risk Women

Cancer Medicine, Volume 14, Issue 18, September 2025.
ABSTRACT Objective The gut microbiome and bile acids (BAs) likely influence colorectal cancer (CRC) development and disparities. We conducted a nested case–control study of the associations of the colon tissue microbiome and circulating BAs with colorectal adenoma prevalence in the previously conducted multi‐center Colorectal Neoplasia Screening with ...
Doratha A. Byrd, Maria F. Gomez, Stephanie R. Hogue, Jessica R. Burns, Nate Smith, Joshua Sampson, Erikka Loftfield, Patricia G. Wolf, Yunhu Wan, Andrew Warner, Belynda Hicks, Casey Dagnall, Kristine Jones, Youngchul Kim, Jin Xu, Jianxin Shi, Rashmi Sinha, Emily Vogtmann   +17 more
wiley   +1 more source

Mutations predisposing to hereditary nonpolyposis colorectal cancer: database and results of a collaborative study. The International Collaborative Group on Hereditary Nonpolyposis Colorectal Cancer.

, 1997
BACKGROUND & AIMS: Germline mutations in four DNA mismatch repair genes are known to cause susceptibility to hereditary nonpolyposis colorectal cancer (HNPCC).
Peltomäki P, PONZ DE LEON, Maurizio, The International Collaborative Group on Hereditary Nonpolyposis Colorectal Cancer, Vasen HF   +3 more
core  

Explanations of risk in families without identified mutations for hereditary nonpolyposis colorectal cancer.

, 2010
Genetic testing for hereditary forms of cancer does not always identify a causative mutation. Little is known about personal or family response to these indeterminate results when a hereditary form of cancer is suspected.
Ersig, Anne L, Hadley, Donald W, Koehly, Laura M, Ayres, Lioness   +3 more
core   +1 more source

Meat and fish consumption, APC gene mutations and hMLH1 expression in colon and rectal cancer: a prospective cohort study (The Netherlands). [PDF]

, 2005
OBJECTIVE: The aim of this study was to investigate the associations between meat and fish consumption and APC mutation status and hMLH1 expression in colon and rectal cancer.
Roemen, Guido M J M, Brandt, P.A. van den, Goldbohm, R.A., Goldbohm, R Alexandra, Lentjes, Marjolein H F M, Lentjes, Marjolein HFM, van den Brandt, Piet A, Wark, Petra A.; id_orcid, Goldbohm, R. Alexandra, Van Den Brandt, Piet A., Veer, P. van 't, van 't Veer, Pieter, Bruine, A.P., de, Weijenberg, Matty P., Weijenberg, Matty P, Roemen, G.M.J.M., de Bruïne, Adriaan P, de Goeij, Anton FPM, Wark, P.A., De Goeij, Anton F P M, Veer, P., van 't, Bruïne, A.P. de, Brink, M., van 't Veer, P., van den Brandt, P.A., Luchtenborg, M., Goeij, A.F.P.M. de, De Bruïne, Adriaan P., de Bruine, A.P., Weijenberg, M.P., Wark, Petra A, Lüchtenborg, Margreet, Roemen, Guido MJM, Brink, Mirian, de Goeij, A.F., Goeij, A.F.P.M., de, Lentjes, M.H.F.M., de Goeij, A.F.P.M., Van't Veer, Pieter, Brandt, P.A., van den   +39 more
core   +1 more source

SPECIAL FEATURES OF CARCINOGENESIS OF COLON ADENOCARCINOMA

Сибирский онкологический журнал, 2016
Colorectal cancer is one of the most common malignancies and the leading cause of cancer-related death. There are 4 basic colon carcinogenic steps: malignant transformation of adenoma into carcinoma; HNPCC (hereditary nonpolyposis colon cancer); cancer ...
G. A. Raskin, S. V. Petrov, R. V. Orlova
doaj  

Quality of Life in Adult Individuals Living With or at Risk of a Hereditary Cancer Predisposition Syndrome: A Scoping Review of the Qualitative Literature

Cancer Medicine, Volume 14, Issue 18, September 2025.
ABSTRACT Background The in‐depth understanding of the impact of a hereditary cancer predisposition syndrome (HCPS) on the health‐related quality of life (HRQOL) of individuals with a hereditary cancer burden contributes to the improvement of counselling strategies as well as care planning and informs the development of patient‐reported outcome measures
M. Sztankay, S. Wheelwright, V. Vassiliou, E. M. A. Bleiker, B. Rahman, B. Holzner, A. Yener, V. Engele, A. S. Oberguggenberger, EORTC Quality of Life Group   +9 more
wiley   +1 more source

Hereditary Nonpolyposis Colorectal Cancer (HNPCC)/Lynch Syndrome: Surveillance and Diagnostic strategies

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2021
Introduction: Hereditary nonpolyposis colorectal cancer (HNPCC, Lynch syndrome) is an autosomal dominant genetic disease. The disease is caused by a mutation in one of four genes of the DNA mismatch repair system and increases the risk for various ...
Mohammad Hassan Jokar, Sima Sedighi, Maliheh Moradzadeh   +2 more
doaj  

Cancer risk in families with hereditary nonpolyposis colorectal cancer diagnosed by mutation analysis

, 1996
Background & Aims: Hereditary nonpolyposis colorectal cancer is characterized by early-onset colorectal cancer and the occurrence of various other cancers, The recent isolation of four mismatch repair genes responsible for hereditary nonpolyposis ...
Menko, F. H., Mohr, J., Kleibeuker, JH, Bisgaard, M. L., Khan, P. M., Kleibeuker, J. H., MeijersHeijboer, EH, Varesco, L, Vasen, H. F., Vasen, H. F. A., Wijnen, J. T., Taal, BG, Meijers-Heijboer, E. H., Mohr, J, Bertario, L., Bertario, L, Bisgaard, ML, Wijnen, JT, Menko, FH, Varesco, L., Khan, PM, Griffioen, G, Fodde, R, Vasen, HFA, Nagengast, FM, Griffioen, G., Fodde, R., Taal, B. G., Nagengast, F. M.   +28 more
core   +2 more sources

Ileocecal Adenocarcinoma and Ureteral Transitional Cell Carcinoma with Multiple Sebaceous Tumors and Keratoacanthomas in a Case of Muir-Torre Syndrome

Dermatology Research and Practice, 2010
Cutaneous neoplasms including sebaceous tumors, keratoacanthomas, and basal cell carcinomas with sebaceous differentiation can be markers of internal malignancy associated with the Muir-Torre Syndrome (MTS).
Michael C. Lynch, Bryan E. Anderson
doaj   +1 more source

Hereditary Colorectal Cancer (CRC) Program in Latvia

Hereditary Cancer in Clinical Practice, 2003
Introduction The aim of the study is to evaluate the incidence and phenotype - genotype characteristics of hereditary colorectal cancer syndromes in Latvia in order to develop the basis of clinical management for patients and their relatives affected by ...
Irmejs Arvids, Gardovskis Andris, Borosenko Viktors, Bitina Marianna, Aigare Diana, Kurzawski Grzegorz, Suchy Janina, Górski Bohdan, Gardovskis Janis   +8 more
doaj   +1 more source