Results 61 to 70 of about 9,940 (218)

Ileocecal Adenocarcinoma and Ureteral Transitional Cell Carcinoma with Multiple Sebaceous Tumors and Keratoacanthomas in a Case of Muir-Torre Syndrome

Dermatology Research and Practice, 2010
Cutaneous neoplasms including sebaceous tumors, keratoacanthomas, and basal cell carcinomas with sebaceous differentiation can be markers of internal malignancy associated with the Muir-Torre Syndrome (MTS).
Michael C. Lynch, Bryan E. Anderson
doaj   +1 more source

Hereditary Colorectal Cancer (CRC) Program in Latvia

Hereditary Cancer in Clinical Practice, 2003
Introduction The aim of the study is to evaluate the incidence and phenotype - genotype characteristics of hereditary colorectal cancer syndromes in Latvia in order to develop the basis of clinical management for patients and their relatives affected by ...
Irmejs Arvids, Gardovskis Andris, Borosenko Viktors, Bitina Marianna, Aigare Diana, Kurzawski Grzegorz, Suchy Janina, Górski Bohdan, Gardovskis Janis   +8 more
doaj   +1 more source

Microsatellite Instability in the Tumor Microenvironment: The Role of Inflammation and the Microbiome

Cancer Medicine, Volume 14, Issue 8, April 2025.
The microbiome, an environmental factor, can contribute to DNA damage and affect mutation accumulation. Infections with genotoxin‐producing pathobionts can induce inflammation and oxidative stress through reactive nitrogen and oxygen species, which may influence MSI.
Elizabeth Vargas‐Castellanos, Andrés Rincón‐Riveros   +1 more
wiley   +1 more source

Identification of Diagnostic Biomarkers for Colorectal Polyps Based on Noninvasive Urinary Metabolite Screening and Construction of a Nomogram

Cancer Medicine, Volume 14, Issue 7, April 2025.
ABSTRACT Purpose/Backgrounds Colorectal polyps (CRPs) are precursors to colorectal cancer (CRC), and early detection is crucial for prevention. Traditional diagnostic methods are invasive, prompting a need for noninvasive biomarkers. This study aimed to identify urinary metabolite biomarkers for diagnosing CRPs and construct a diagnostic nomogram based
Yang Xie, Yiyi Jin, Zide Liu, Jun Li, Qing Tao, Yonghui Wu, Youxiang Chen, Chunyan Zeng   +7 more
wiley   +1 more source

HEREDITARY NON-POLYPOSIS COLORECTAL CANCER (LYNCH SYNDROME) PADA WANITA UMUR 16 TAHUN

Majalah Kedokteran Andalas, 2011
AbstrakKanker kolorektal menduduki peringkat ketiga jenis kanker yang paling sering terjadi di dunia. Sekitar 3% kasus kanker kolorektal merupakan jenis hereditary non polyposis colorectal cancer (HNPCC)/Lynch syndrome, yang sering muncul pada usia muda.
Asril Zahari, Sudiyatmo Sudiyatmo
doaj   +1 more source

Lack of association between screening interval and cancer stage in Lynch syndrome may be accounted for by over-diagnosis; a prospective Lynch syndrome database report

Hereditary Cancer in Clinical Practice, 2019
Background Recent epidemiological evidence shows that colorectal cancer (CRC) continues to occur in carriers of pathogenic mismatch repair (path_MMR) variants despite frequent colonoscopy surveillance in expert centres.
Toni T. Seppälä, Aysel Ahadova, Mev Dominguez-Valentin, Finlay Macrae, D. Gareth Evans, Christina Therkildsen, Julian Sampson, Rodney Scott, John Burn, Gabriela Möslein, Inge Bernstein, Elke Holinski-Feder, Kirsi Pylvänäinen, Laura Renkonen-Sinisalo, Anna Lepistö, Charlotte Kvist Lautrup, Annika Lindblom, John-Paul Plazzer, Ingrid Winship, Douglas Tjandra, Lior H. Katz, Stefan Aretz, Robert Hüneburg, Stefanie Holzapfel, Karl Heinimann, Adriana Della Valle, Florencia Neffa, Nathan Gluck, Wouter H. de Vos tot Nederveen Cappel, Hans Vasen, Monika Morak, Verena Steinke-Lange, Christoph Engel, Nils Rahner, Wolff Schmiegel, Deepak Vangala, Huw Thomas, Kate Green, Fiona Lalloo, Emma J. Crosbie, James Hill, Gabriel Capella, Marta Pineda, Matilde Navarro, Ignacio Blanco, Sanne ten Broeke, Maartje Nielsen, Ken Ljungmann, Sigve Nakken, Noralane Lindor, Ian Frayling, Eivind Hovig, Lone Sunde, Matthias Kloor, Jukka-Pekka Mecklin, Mette Kalager, Pål Møller   +56 more
doaj   +1 more source

The story of hereditary nonpolyposis colorectal cancer: celebrating the spirit of investigation. [PDF]

IGIE, 2023
Lynch PM, Ge PS.
europepmc   +1 more source

Reduced expression of alanyl aminopeptidase is a robust biomarker of non-familial adenomatous polyposis and non-hereditary nonpolyposis colorectal cancer syndrome early-onset colorectal cancer. [PDF]

Cancer Med, 2023
Ha YJ, Shin YJ, Tak KH, Park JL, Kim JH, Lee JL, Yoon YS, Kim CW, Kim SY, Kim JC.   +9 more
europepmc   +1 more source

Three synchronous primary carcinomas in a patient with HNPCC associated with a novel germline mutation in MLH1: Case report

World Journal of Surgical Oncology, 2009
Background MLH1 is one of six known genes responsible for DNA mismatch repair (MMR), whose inactivation leads to HNPCC. It is important to develop genotype-phenotype correlations for HNPCC, as is being done for other hereditary cancer syndromes, in order
Yee Herman, Reich Elsa W, Huang William C, Moore Harvey G, Valenzuela Cristian D, Ostrer Harry, Pachter H Leon   +6 more
doaj   +1 more source

DNA Methylation and MicroRNAs as Biomarkers in Hereditary Nonpolyposis of Colorectal Cancer Patients: A Systematic Review

, 2023
Gregorio Rangel
openalex   +2 more sources