Results 61 to 70 of about 10,129 (212)

Risk of colorectal cancer by family history of both colorectal carcinomas and colorectal polyps: a nationwide cohort study

Cancer Communications, Volume 45, Issue 11, Page 1407-1416, November 2025.
Abstract Background The increased risk of colorectal cancer (CRC) associated with family history of both colorectal in situ or invasive carcinomas (Stage 0 to IV) and colorectal polyps is attributed solely to family history of CRC, resulting in an underestimation of the actual risk. We aimed to assess the association between overall and early‐onset CRC
Yuqing Hu, Elham Kharazmi, Qunfeng Liang, Hermann Brenner, Jan Sundquist, Kristina Sundquist, Mahdi Fallah   +6 more
wiley   +1 more source

Knowledge about hereditary nonpolyposis colorectal cancer; mutation carriers and physicians at equal levels

BMC Medical Genetics, 2009
Background Identification and adequate management of individuals at risk for hereditary nonpolyposis colorectal cancer (HNPCC) is crucial since surveillance programmes reduce morbidity and mortality.
Bendahl Pär-Ola, Carlsson Christina, Domanska Katarina, Nilbert Mef   +3 more
doaj   +1 more source

Inaccuracy of Ureteroscopic Biopsy in Upper Tract Urothelial Carcinoma Can Lead to False Therapeutic Decisions: A Case Report

Clinical Case Reports, Volume 13, Issue 11, November 2025.
ABSTRACT Do not rely solely on negative endoscopic biopsies when diagnosing upper tract urothelial carcinoma (UTUC). Repeat ureteroscopy with biopsy if initial results are negative to reduce false negatives. Frozen section analysis (FSA) can provide rapid intraoperative confirmation and guide treatment decisions.
Ayoub Hidayat‐Allah, Frank Friedersdorff   +1 more
wiley   +1 more source

GSTP1 and GSTA1 polymorphisms interact with cruciferous vegetable intake in colorectal adenoma risk.

, 2005
The possible interplay between cruciferous vegetable consumption, functional genetic variations in glutathione S-transferases (GST) M1, T1, P1, and A1, and colorectal adenomas, was investigated in a Dutch case-control study.
Nagengast, Fokko M, Visker, Marleen H P W, Aarts, Jac M M J G, Kampman, Ellen, Visker, Marleen HPW, Nagengast, Fokko M., Kok, Frans J., Tijhuis, Mariken J, Wark, Petra A, Wark, Petra A.; id_orcid, Tijhuis, Mariken J., Aarts, Jac MMJG, Kok, Frans J   +12 more
core   +1 more source

Hereditary nonpolyposis colorectal cancer in endometrial cancer patients [PDF]

International Journal of Cancer, 2007
AbstractEndometrial cancer is the second most common cancer in hereditary nonpolyposis colorectal cancer (HNPCC). It has often been overlooked to explore the possibility of HNPCC in endometrial cancer patients. Our study was to investigate how many HNPCC patients existed among endometrial cancer patients.
Sang Nam, Yoon, Ja-Lok, Ku, Young-Kyoung, Shin, Kyung-Hee, Kim, Jin-Sung, Choi, Eun-Ja, Jang, Hyoung-Chul, Park, Duck-Woo, Kim, Min A, Kim, Woo Ho, Kim, Taek Sang, Lee, Jae Weon, Kim, Noh-Hyun, Park, Yong-Sang, Song, Soon-Beom, Kang, Hyo-Pyo, Lee, Seung-Yong, Jeong, Jae-Gahb, Park   +17 more
openaire   +2 more sources

A rare case of colonic adenocarcinoma in a pediatric patient

JPGN Reports, Volume 6, Issue 4, Page 400-403, November 2025.
Abstract Lynch syndrome (LS) is an autosomal dominant condition caused by a loss of function in the deoxyribonucleic acid mismatch repair system. This case report presents a 17‐year‐old male with abdominal pain, weight loss, and anemia who was diagnosed with LS‐associated adenocarcinoma of the colon in the setting of a mutS homolog 6 genetic mutation ...
Christine Kaba, Kelsey Chatman, Nicole Hames, Jose E. Velazquez Vega, Hillary Bashaw   +4 more
wiley   +1 more source

The population incidence of cancer [PDF]

, 2009
In this thesis stochastic techniques are used in attempts to understand cancer risk, its relationship to patient age and genotype, as well as its distribution in human populations. The starting point for the thesis is the general observation that cancer
Hornsby, C, Hornsby, C.
core  

Cigarette smoking and K-ras mutations in pancreas, lung and colorectal adenocarcinomas: etiopathogenic similarities, differences and paradoxes.

, 2009
Surprisingly different frequencies and patterns of K-ras mutations are observed in human adenocarcinomas of the pancreas, colorectum and lung. Their respective relationships with smoking are apparently paradoxical. We evaluated all the available types of
Real, F.X., Vineis, Paolo, Wark, P.A., Malats, N., Kampman, Ellen, Real, Francisco X., Vineis, P., Real, Francisco X, Crous-Bou, Marta, Crous-Bou, M., Wark, Petra A, Kampman, E., Wark, Petra A.; id_orcid, Porta, Miquel, Porta, M., Malats, Núria   +15 more
core   +1 more source

Integrin β6 expression in colorectal cancer cells promotes liver metastasis through enhanced adhesion to endothelial fibronectin

International Journal of Cancer, Volume 157, Issue 7, Page 1481-1495, 1 October 2025.
What's New? Integrins are critical mediators of cell adhesion and migration and have been implicated in cancer progression. Here, the authors show that endothelial cells in target organs of colorectal cancer metastasis express fibronectin, and that colorectal cancer tumour cells can bind fibronectin through integrin β6. This interaction is resistant to
Chiara Van Passen, Julia Krug, Luisa Weiß, Mariam Mohamed Abdou, Philipp Tripal, Benjamin Schmid, René Krüger, Yanmin Lyu, Bisan Abdalfatah Zohud, Katja Petter, Carol Geppert, Susanne Merkel, Barbara Bärthlein, Philipp Busenhart, Michael Scharl, Elisabeth Naschberger, Michael Stürzl   +16 more
wiley   +1 more source

Colorectal cancers with microsatellite instability display mRNA expression signatures characteristic of increased immunogenicity

, 2004
Background Colorectal cancers displaying high-degree microsatellite instability (MSI-H) have an improved prognosis compared to microsatellite stable (MSS) cancers.
Huang Fei, Bustin, SA, Shaw Peter M, Roger Feakins, Hands Rebecca E, Banerjea, A, Fei Huang, Stephen A Bustin, Bustin Stephen A, Han Xia, Dorudi, S, Shafi Ahmed, Ayan Banerjea, Hands, RE, Ahmed, S, Feakins, R, Han, X, Feakins Roger, Sina Dorudi, Shaw, PM, Peter M Shaw, Banerjea Ayan, Xia Han, Huang, F, Rebecca E Hands, Dorudi Sina, Ahmed Shafi   +26 more
core   +1 more source