Results 161 to 170 of about 17,722 (214)

From allergy to arrhythmia - electrophysiological basis for the antiarrhythmic properties of antazoline. [PDF]

Front Pharmacol
Wiedmann F, Prodanova A, Kraft M, Weitkamp FM, Paasche A, Goetz C, Schmidt C.   +6 more
europepmc   +1 more source

Express with caution: Epitope tags and cDNA variants effects on hERG channel trafficking, half-life and function. [PDF]

J Cardiovasc Electrophysiol, 2017
Osterbur Badhey ML, Bertalovitz AC, McDonald TV.   +2 more
europepmc   +1 more source

Investigating the utility of adult zebrafish ex vivo whole hearts to pharmacologically screen hERG channel activator compounds.

Am J Physiol Regul Integr Comp Physiol, 2019
Hull CM, Genge CE, Hobbs Y, Rayani K, Lin E, Gunawan M, Shafaattalab S, Tibbits GF, Claydon TW.   +8 more
europepmc   +1 more source

SPARC: a structural pathogenicity algorithm for risk classification of hERG variants. [PDF]

Europace
Chatelain FC, de Oliveira BR, Grataloup G, Robert N, Alameh M, Thollet A, Montnach J, Feliciangeli S, Rio A, Bibault F, Bichet D, Bignucolo O, Extramiana F, Majumder R, Schott JJ, Probst V, Denjoy I, Lesage F, Loussouarn G, De Waard M.   +19 more
europepmc   +1 more source

Personalized in vitro models reveal functional impact of a <i>KCNH2</i> mutation and enable drug screening in LQTS2. [PDF]

Heart Rhythm O2
Zheng B, Zhu Y, Sun M, Cheng H, Zhang S, Cai C, Gu K, An Y, Ding X, Zhang F, Cui C, Chen M.   +11 more
europepmc   +1 more source

Second-generation antipsychotics - Cardiac ion channel modulation and QT interval disturbances: A review. [PDF]

Biomol Biomed
Erkan O, Dai AS, Ozturk N, Ozdemir S.
europepmc   +1 more source

Amiodarone irrecoverably impairs the function of human ether-a-go-go-related gene potassium channels. [PDF]

Mol Pharmacol
Gelman I, Li W, Guo J, Bogart-Cherry R, Tomei N, Sharma N, Pan A, Yang T, Baranchuk A, El-Diasty M, Zhang S.   +10 more
europepmc   +1 more source

Erratum: Mechanism and pharmacological rescue of berberine-induced hERG channel deficiency [Corrigendum]. [PDF]

Drug Des Devel Ther, 2016
europepmc   +1 more source

Improving hERG Cardiotoxicity Prediction via SMILES Transformer, Molecular Fingerprints, and Layer-Wise Self-Adaptive Graph Attention Network. [PDF]

ACS Omega
Beidja C, Bousselham A, En-Naimani Z, Mestari M.   +3 more
europepmc   +1 more source

Advancing Torsades de pointes risk prediction: unveiling the role of drug metabolites through molecular docking. [PDF]

Toxicol Res (Camb)
Bilgin E, Tugcu G, Aydin A.
europepmc   +1 more source