Results 31 to 40 of about 183,086 (327)

DNA methyltransferase activity in the basolateral amygdala is critical for reconsolidation of a heroin reward memory

Frontiers in Molecular Neuroscience, 2022
The persistence of drug memory contributes to relapse to drug seeking. The association between repeated drug exposure and drug-related cues leads to cravings triggered by drug-paired cues.
Shuyi Qian, Cuijie Shi, Shihao Huang, Chang Yang, Yixiao Luo   +4 more
doaj   +1 more source

Heroin maintenance for chronic heroin-dependent individuals [PDF]

Cochrane Database of Systematic Reviews, 2010
Several types of medications have been used for stabilizing heroin users: Methadone, Buprenorphine and levo-alpha-acetyl-methadol (LAAM.) The present review focuses on the prescription of heroin to heroin-dependent individuals.To compare heroin maintenance to methadone or other substitution treatments for opioid dependence regarding: efficacy and ...
Marica, Ferri, Marina, Davoli, Carlo A, Perucci   +2 more
openaire   +3 more sources

Chasing the dragon – an overview of heroin trafficking [PDF]

, 2016
There are many problems encountered during the attempt to tackle the heroin trade on a global level. Afghanistan is largely responsible for the production of heroin, providing a global distribution amount of 75%.
Carvetta, CA, O'Hagan, A
core   +1 more source

Buprenorphine is a weak dopamine releaser relative to heroin, but its pretreatment attenuates heroin‐evoked dopamine release in rats

Neuropsychopharmacology Reports, 2020
Aims The United States of America is currently in an opioid epidemic. Heroin remains the most lethal opioid option with its death rate increasing by over 500% in the last decade.
Dominic P. Isaacs, Ryan P. Leman, Thomas J. Everett, Hendrick Lopez‐Beltran, Lindsey R. Hamilton, Erik B. Oleson   +5 more
doaj   +1 more source

The Role of the Posterior Paraventricular Nucleus of the Thalamus in Food Deprivation-Induced Heroin-Seeking Relapse, in Male and Female Rats. [PDF]

Addict Biol
Chemogenetic inhibition of the pPVT resulted in an increase in food‐deprivation‐induced heroin seeking compared to the control group, only in male rats. Chemogenetic excitation of the pPVT resulted in an increase in heroin seeking under food‐deprivation conditions.
Borges C, Darecka A, Mainville-Berthiaume A, Ah-Yen E, Darvishmolla M, Courtemanche R, Shalev U.   +6 more
europepmc   +2 more sources

Association Between Heroin Use and Depression: NHANES 2005-2018. [PDF]

Addict Biol
Graphical summary illustrating the association between lifetime heroin use and increased odds of clinically significant depression in US adults, with stronger effects observed among younger individuals and current smokers. ABSTRACT Heroin use and major depression are each leading contributors to global disability and premature mortality, yet evidence ...
Li B, Yang Z, Zhang X, Yang M, Qiu H, Ren Y.   +5 more
europepmc   +2 more sources

Association of frontal gray matter volume and cerebral perfusion in heroin addiction: A multimodal neuroimaging study

Frontiers in Psychiatry, 2013
Structure and function in the human healthy brain are closely related. In patients with chronic heroin exposure, brain imaging studies have identified long-lasting changes in gray matter (GM) volume.
Niklaus eDenier, André eSchmidt, Hana eGerber, Otto eSchmid, Anita eRiecher-Rössler, Gerhard eWiesbeck, Christian G. Huber, Undine E. Lang, Ernst-Wilhelm eRadue, Marc eWalter, Stefan eBorgwardt, Stefan eBorgwardt   +11 more
doaj   +1 more source

A Study to Validate a Self-Reported Version of the ONS Drug Dependence Questionnaire [PDF]

, 2011
Aim: A prospective study to establish the reliability of a self-completion version of the Office for National Statistics (ONS) questionnaire for assessing drug dependence of substance misuse clients.
Christo G., Darke S., Gossop M., Jehanli A., Lundy A., Luty J., M. Uddin, Marsden J., McLellan A. T., Poole W. K., R. Holland, Rosen C. S., Schwartz R. H., Sherman M. F., Simpson D. D., Singleton N., V. Maskrey, Vivancos R.   +17 more
core   +1 more source

Orthoptic status before and immediately after heroin detoxification [PDF]

, 2004
Aim: To determine whether changes in orthoptic status take place during withdrawal from heroin and/or methadone. Method: A prospective study of patients, using a repeated measures design, attending a 5 day naltrexone compressed opiate detoxification ...
Beaini, A.Y., Carr, M.P., Firth, A.Y., Pulling, S.   +3 more
core   +2 more sources

Using a pragmatically adapted, low-cost contingency management intervention to promote heroin abstinence in individuals undergoing treatment for heroin use disorder in UK drug services (PRAISE): a cluster randomised trial

BMJ Open, 2021
Introduction Most individuals treated for heroin use disorder receive opioid agonist treatment (OAT)(methadone or buprenorphine). However, OAT is associated with high attrition and persistent, occasional heroin use.
Julian Mutz, Andrew Pickles, Sarah Byford, John Dunn, Kimberley Goldsmith, Franziska Mosler, Tim Weaver, James Shearer, Emily Finch, John Strang, Clare Davey, Stephen Pilling, Anthony Glasper, Nicola Metrebian, Jennifer Hellier, Luke Mitcheson, Prun Bijral, Nadine Bogdan, Owen Bowden-Jones, Edward Day, Sam Forshall, Shabana Akhtar, Jalpa Bajaria, Carmel Bennett, Elizabeth Bishop, Vikki Charles, Roopal Desai, Claire Goodfellow, Farjana Haque, Nicholas Little, Hortencia McKechnie, Jo Morris, Ruth Pauli, Dilkushi Poovendran, Elizabeth Phillips   +34 more
doaj   +1 more source