Results 31 to 40 of about 100,982 (338)
Pathways to age of onset of heroin use: a structural model approach exploring the relationship of the COMT gene, impulsivity and childhood trauma. [PDF]
PLoS ONE, 2012 The interaction of the association of dopamine genes, impulsivity and childhood trauma with substance abuse remains unclear.To clarify the impacts and the interactions of the Catechol -O-methyltransferase (COMT) gene, impulsivity and childhood trauma on ...
Ting Li +8 more
doaj +1 more source
Dopamine neurons projecting to medial shell of the nucleus accumbens drive heroin reinforcement
bioRxiv, 2018 The dopamine (DA) hypothesis posits the increase of mesolimbic dopamine levels as a defining commonality of addictive drugs, initially causing reinforcement, eventually leading to compulsive consumption.
Julie Corre +6 more
semanticscholar +1 more source
Frontiers in Molecular Neuroscience, 2022 Reconsolidation of heroin-associated memory is an independent memory process that occurs following retrieval, which is essential for the sustained capacity of an associative drug stimulus to precipitate heroin-seeking.
Haoyu Li +17 more
doaj +1 more source
Addiction, 2004 ABSTRACTAims To describe the eye misalignments that occur during heroin use and heroin detoxification and to give an overview of the management of persisting diplopia (double vision) which results from eye misalignment.Methods A literature review using Medline and the search terms strabismus, heroin and substance withdrawal syndrome is presented ...
openaire +3 more sources
Quality of life and its correlates among heroin users in Taiwan
Kaohsiung Journal of Medical Sciences, 2011 The aims of this study were to compare the quality of life (QOL) between subjects with and without heroin use and to examine the association of QOL with sociodemographic characteristics, characteristics of heroin use, family support, and depression among
Chia-Nan Yen +9 more
doaj +1 more source
Heroin maintenance for chronic heroin-dependent individuals [PDF]
Cochrane Database of Systematic Reviews, 2010 Several types of medications have been used for stabilizing heroin users: Methadone, Buprenorphine and levo-alpha-acetyl-methadol (LAAM.) The present review focuses on the prescription of heroin to heroin-dependent individuals.To compare heroin maintenance to methadone or other substitution treatments for opioid dependence regarding: efficacy and ...
Carlo A. Perucci +2 more
openaire +4 more sources
Pain Physician, 2018 The opioid epidemic has been called the "most consequential preventable public health problem in the United States." Though there is wide recognition of the role of prescription opioids in the epidemic, evidence has shown that heroin and synthetic ...
L. Manchikanti +5 more
semanticscholar +1 more source
Should heroin be prescribed to heroin misusers? No [PDF]
BMJ, 2008 Prescribing heroin to heroin addicts is a strategy beloved by top police officers1 and successive home secretaries.2 It is a strategy, though, borne of utter frustration at our seeming inability to tackle an escalating drug problem. If you cannot stop addicts committing crimes to fund their drug habit then, so the argument goes, the next best thing is ...
openaire +3 more sources
Frontiers in Psychiatry, 2013 Structure and function in the human healthy brain are closely related. In patients with chronic heroin exposure, brain imaging studies have identified long-lasting changes in gray matter (GM) volume.
Niklaus eDenier +11 more
doaj +1 more source
Neuropsychopharmacology Reports, 2020 Aims The United States of America is currently in an opioid epidemic. Heroin remains the most lethal opioid option with its death rate increasing by over 500% in the last decade.
Dominic P. Isaacs +5 more
doaj +1 more source