Results 31 to 40 of about 173,536 (262)
Heroin and its metabolites: relevance to heroin use disorder
Translational Psychiatry, 2023 Heroin is an opioid agonist commonly abused for its rewarding effects. Since its synthesis at the end of the nineteenth century, its popularity as a recreational drug has ebbed and flowed.
Michele Stanislaw Milella +5 more
doaj +1 more source
Reciprocal Substitution Between Methamphetamine and Heroin in Terms of Reinforcement Effects in Rats
Frontiers in Psychiatry, 2020 Heroin and methamphetamine are both popular illicit drugs in China. Previous clinical data showed that habitual users of either heroin or methamphetamine abuse the other drug for substitution in case of unavailability of their preferred drug. The present
Di-sen Mei +9 more
doaj +1 more source
The newer opioid agonist treatment with lower substitutive opiate doses is associated with better toxicology outcome than the older harm reduction treatment [PDF]
, 2016 Background: Charge-free heroin use disorder treatment in Italy follows two main approaches, i.e., harm reduction treatment (HRT) strategy in community low-threshold facilities for drug addiction and opioid agonist treatment (OAT) in high-threshold ...
Bacciardi, Silvia +8 more
core +1 more source
Should heroin be prescribed to heroin misusers? No [PDF]
BMJ, 2008 Prescribing heroin to heroin addicts is a strategy beloved by top police officers1 and successive home secretaries.2 It is a strategy, though, borne of utter frustration at our seeming inability to tackle an escalating drug problem. If you cannot stop addicts committing crimes to fund their drug habit then, so the argument goes, the next best thing is ...
openaire +3 more sources
Frontiers in Psychiatry, 2013 Structure and function in the human healthy brain are closely related. In patients with chronic heroin exposure, brain imaging studies have identified long-lasting changes in gray matter (GM) volume.
Niklaus eDenier +11 more
doaj +1 more source
Heroin maintenance for chronic heroin-dependent individuals [PDF]
Cochrane Database of Systematic Reviews, 2010 Several types of medications have been used for stabilizing heroin users: Methadone, Buprenorphine and levo-alpha-acetyl-methadol (LAAM.) The present review focuses on the prescription of heroin to heroin-dependent individuals.To compare heroin maintenance to methadone or other substitution treatments for opioid dependence regarding: efficacy and ...
Carlo A. Perucci +2 more
openaire +4 more sources
Quality of life and its correlates among heroin users in Taiwan
Kaohsiung Journal of Medical Sciences, 2011 The aims of this study were to compare the quality of life (QOL) between subjects with and without heroin use and to examine the association of QOL with sociodemographic characteristics, characteristics of heroin use, family support, and depression among
Chia-Nan Yen +9 more
doaj +1 more source
Pathways to age of onset of heroin use: a structural model approach exploring the relationship of the COMT gene, impulsivity and childhood trauma. [PDF]
PLoS ONE, 2012 The interaction of the association of dopamine genes, impulsivity and childhood trauma with substance abuse remains unclear.To clarify the impacts and the interactions of the Catechol -O-methyltransferase (COMT) gene, impulsivity and childhood trauma on ...
Ting Li +8 more
doaj +1 more source
Frontiers in Molecular Neuroscience, 2022 Reconsolidation of heroin-associated memory is an independent memory process that occurs following retrieval, which is essential for the sustained capacity of an associative drug stimulus to precipitate heroin-seeking.
Haoyu Li +17 more
doaj +1 more source
Heroin type, injecting behavior, and HIV transmission. A simulation model of HIV incidence and prevalence. [PDF]
, 2019 Background and aimsUsing mathematical modeling to illustrate and predict how different heroin source-forms: "black tar" (BTH) and powder heroin (PH) can affect HIV transmission in the context of contrasting injecting practices. By quantifying HIV risk by
Bobashev, Georgiy +5 more
core +1 more source