Results 41 to 50 of about 49,559 (233)

Using a pragmatically adapted, low-cost contingency management intervention to promote heroin abstinence in individuals undergoing treatment for heroin use disorder in UK drug services (PRAISE): a cluster randomised trial

BMJ Open, 2021
Introduction Most individuals treated for heroin use disorder receive opioid agonist treatment (OAT)(methadone or buprenorphine). However, OAT is associated with high attrition and persistent, occasional heroin use.
Julian Mutz, Andrew Pickles, Sarah Byford, John Dunn, Kimberley Goldsmith, Franziska Mosler, Tim Weaver, James Shearer, Emily Finch, John Strang, Clare Davey, Stephen Pilling, Anthony Glasper, Nicola Metrebian, Jennifer Hellier, Luke Mitcheson, Prun Bijral, Nadine Bogdan, Owen Bowden-Jones, Edward Day, Sam Forshall, Shabana Akhtar, Jalpa Bajaria, Carmel Bennett, Elizabeth Bishop, Vikki Charles, Roopal Desai, Claire Goodfellow, Farjana Haque, Nicholas Little, Hortencia McKechnie, Jo Morris, Ruth Pauli, Dilkushi Poovendran, Elizabeth Phillips   +34 more
doaj   +1 more source

Understanding Consumption of Illicit Drugs and New Psychoactive Substances in Australia by Triangulating Drug Checking and Wastewater‐Based Epidemiology

Drug Testing and Analysis, EarlyView.
First Australian study combining wastewater‐based epidemiology and drug checking, demonstrating how complementary data sources enhance monitoring of illicit drugs and emerging psychoactive substances during high‐use periods. ABSTRACT Consumption of psychotropic drugs is a major economic and public health challenge in Australia.
Muhammad Usman, Malcolm McLeod, Dhayaalini Nadarajan, Joseph Clokey, Pritesh Prasad, Rory Verhagen, Benjamin Tscharke, Maurizio Quinto, Richard Bade   +8 more
wiley   +1 more source

Micro‐QuEChERS Extraction for Broad‐Spectrum LC‐QQQ‐MS Quantification of Nitazene Analogs in Plasma: A Validated Method With Casework Application

Drug Testing and Analysis, EarlyView.
Micro‐QuEChERS sample preparation coupled to LC‐QQQ‐MS enabled sensitive quantification of nitazene analogs in 100 μL of plasma. The validated method provided low detection limits and was successfully applied to an authentic intoxication case involving N‐pyrrolidino protonitazene, supporting clinical and forensic toxicology workflows.
Karla A. O. Souza, Náthaly C. B. F. Santos, Rafael Lanaro, Sara E. Walton, Alex J. Krotulski, Barry K. Logan, Mauricio Yonamine, Jose Luiz Costa   +7 more
wiley   +1 more source

Gender‐based violence during pregnancy and adverse perinatal outcomes in an urban low‐ and middle‐income setting: A prospective cohort study

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To evaluate the association between gender‐based violence (GBV) assessed in early pregnancy and adverse perinatal outcomes using relative and absolute effect measures in an urban low‐ and middle‐income setting. Methods We conducted a prospective cohort study including 3890 singleton pregnancies recruited from two public healthcare ...
Elsa Romelia Moreno‐Verduzco, Javier Perez Duran, Irma Eloisa Monroy‐Muñoz, Juan Mario Solis‐Paredes, Salvador Espino‐y‐Sosa, Raigam Martinez‐Portilla, Johnatan Torres‐Torres   +6 more
wiley   +1 more source

Intranasal diamorphine population pharmacokinetics modeling and simulation in pediatric breakthrough pain

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 435-447, March 2025.
Abstract Intranasal diamorphine (IND), approved for managing breakthrough pain in the UK, has been identified as an acceptable alternative offering effective, expedient, and less traumatic analgesia for children. However, the current dose regimen in pediatric populations relies on clinical expertise while the pharmacokinetics properties are poorly ...
Lianjin Cai, Jingchen Zhai, Beihong Ji, Fengyang Han, Taoyu Niu, Luxuan Wang, Junmei Wang   +6 more
wiley   +1 more source

Nanoelectronic Detection of Opioids: Machine Learning‐Powered Screening With Carbon Nanotube Field‐Effect Transistor Sensor Array

Small, EarlyView.
A carbon nanotube field‐effect transistor (NTFET) sensor array is constructed to screen different opioids with machine learning models. Codeine, fentanyl, hydrocodone, and morphine are tested using the NTFET sensor array and classified with both conventional supervised learning models and deep learning models.
Zhengru Liu, Mehdy Dousty, Wenting Shao, Jieyu Wang, Samia Afrin, Wuqi Li, Ervin Sejdić, Alexander Star   +7 more
wiley   +1 more source

Scalable Room‐Temperature Terahertz Graphene Cameras

Small Methods, EarlyView.
ABSTRACT Terahertz (THz) imaging has emerged as a powerful tool for non‐destructive, label‐free analysis across several scientific disciplines, ranging from materials science to biomedical research. By capturing the spatial‐dependent information in a broad range of frequencies, this technique enables the identification of chemical composition ...
Lili Shi, Leonardo Viti, Miriam S. Vitiello   +2 more
wiley   +1 more source

The Dark Pyramid: Unpacking the Multidimensional Nature of the Dark Side of Leadership

British Journal of Management, EarlyView.
Abstract The dark side of leadership has been employed as an umbrella term to cover an array of concepts typically concerned with the dysfunctionality and/or toxicity of individual leaders. As the field of leadership studies moves towards ‘post‐heroic’ perspectives, we apply the same ontological positioning, adopting a ‘post‐villainous’ perspective in ...
Peter Stephenson, Richard Bolden, Morgen Witzel   +2 more
wiley   +1 more source

Impacts of Global Cannabis Policy Changes on Substance Use: A Systematic Review of Quasi‐Experimental Studies

The Milbank Quarterly, EarlyView.
Policy Points The liberalization of medical and recreational cannabis policies may increase cannabis initiation across age groups, with increased prevalence of cannabis use among young adults and adults and weaker effects among youth. Evidence also suggests increases in cannabis‐related health care utilization among adults.
SARAH B. WINDLE, PETER M. SOCHA, JASLEEN ARNEJA, SAM HARPER, GENEVIEVE GORE, GENEVIÉVE GARIÉPY, EVA GRAHAM, ANDREA BENEDETTI, ARIJIT NANDI   +8 more
wiley   +1 more source

Masculinity, Prostitution, and the Imaginary Northwest in Chinese Travel Writings About Shanxi and Western Inner Mongolia, 1920–1949

Gender &History, EarlyView.
ABSTRACT This article considers travel writings by metropolitan men in Republican China about Shanxi and western Inner Mongolia as a case study to further explore the transformations and continuities of Chinese masculinities. Drawing upon a range of popular travel narratives, it shows that so‐called “Worn‐Out Shoes (poxie)” – women perceived as ...
Amanda Zhang
wiley   +1 more source