Results 31 to 40 of about 49,559 (233)

Pathways to age of onset of heroin use: a structural model approach exploring the relationship of the COMT gene, impulsivity and childhood trauma. [PDF]

PLoS ONE, 2012
The interaction of the association of dopamine genes, impulsivity and childhood trauma with substance abuse remains unclear.To clarify the impacts and the interactions of the Catechol -O-methyltransferase (COMT) gene, impulsivity and childhood trauma on ...
Ting Li, Jiang Du, Shunying Yu, Haifeng Jiang, Yingmei Fu, Dongxiang Wang, Haiming Sun, Hanhui Chen, Min Zhao   +8 more
doaj   +1 more source

Extracellular signal-regulated kinase in the basolateral amygdala is required for reconsolidation of heroin-associated memory

Frontiers in Molecular Neuroscience, 2022
Reconsolidation of heroin-associated memory is an independent memory process that occurs following retrieval, which is essential for the sustained capacity of an associative drug stimulus to precipitate heroin-seeking.
Haoyu Li, Haoyu Li, Haoyu Li, Ting Hu, Ting Hu, Ting Hu, Yanghui Zhang, Zijin Zhao, Zijin Zhao, Zijin Zhao, Qing Liu, Qing Liu, Qing Liu, Zihua Chen, Zihua Chen, Si Chen, Si Chen, Si Chen   +17 more
doaj   +1 more source

Quality of life and its correlates among heroin users in Taiwan

Kaohsiung Journal of Medical Sciences, 2011
The aims of this study were to compare the quality of life (QOL) between subjects with and without heroin use and to examine the association of QOL with sociodemographic characteristics, characteristics of heroin use, family support, and depression among
Chia-Nan Yen, Carol Sheei-Meei Wang, Tzu-Yun Wang, Hsiao-Fang Chen, Hsun-Cheng Chang, 顏嘉男, 王秀美, 王姿云, 陳小芳, 張訓誠   +9 more
doaj   +1 more source

The societal cost of heroin use disorder in the United States.

PLoS ONE, 2017
ObjectiveHeroin use in the United States has reached epidemic proportions. The objective of this paper is to estimate the annual societal cost of heroin use disorder in the United States in 2015 US dollars.MethodsAn analytic model was created that ...
Ruixuan Jiang, Inyoung Lee, Todd A Lee, A Simon Pickard   +3 more
doaj   +1 more source

Association of frontal gray matter volume and cerebral perfusion in heroin addiction: A multimodal neuroimaging study

Frontiers in Psychiatry, 2013
Structure and function in the human healthy brain are closely related. In patients with chronic heroin exposure, brain imaging studies have identified long-lasting changes in gray matter (GM) volume.
Niklaus eDenier, André eSchmidt, Hana eGerber, Otto eSchmid, Anita eRiecher-Rössler, Gerhard eWiesbeck, Christian G. Huber, Undine E. Lang, Ernst-Wilhelm eRadue, Marc eWalter, Stefan eBorgwardt, Stefan eBorgwardt   +11 more
doaj   +1 more source

Heroin-induced headache in female heroin addicts

Journal of International Medical Research, 2020
Objective To investigate the manifestations and incidence of headaches caused by heroin in Chinese women. Methods This was a survey study conducted from 29 June to 3 July 2015 with women attending the Shanxi Drug Rehabilitation Centre for Women (China ...
Li Li, Shengyuan Yu
doaj   +1 more source

Buprenorphine is a weak dopamine releaser relative to heroin, but its pretreatment attenuates heroin‐evoked dopamine release in rats

Neuropsychopharmacology Reports, 2020
Aims The United States of America is currently in an opioid epidemic. Heroin remains the most lethal opioid option with its death rate increasing by over 500% in the last decade.
Dominic P. Isaacs, Ryan P. Leman, Thomas J. Everett, Hendrick Lopez‐Beltran, Lindsey R. Hamilton, Erik B. Oleson   +5 more
doaj   +1 more source

Aflatoxins and heroin. [PDF]

BMJ, 1989
Sur 13 echantillons d'heroine saisis provenant de pays tropicaux, 4 contiennent de l'aflatoxine B 1 . Des aflatoxines sont decelees dans l'urine de 27 toxicomanes sur 133. L'attention est attiree sur ce nouveau risque d'infection (hepatite, sida) chez les toxicomanes utilisant des injections intra-veineuses, l'aflatoxines ayant des proprietes ...
R G, Hendrickse, S M, Maxwell, R, Young
openaire   +2 more sources

Development of a nalmefene formulation suitable for a community‐use auto‐injector

British Journal of Clinical Pharmacology, EarlyView.
Aim Time to onset of reversal is critical when treating opioid‐induced respiratory depression and hypoxia. This study aimed to develop a formulation of the opioid antagonist nalmefene with an increased absorption rate and reduced time to onset of reversal following intramuscular administration. Methods Several absorption enhancers were screened in rats,
Alessandra Cipriano, Manjunath S. Shet, Hugh Huang, Ronnie Ortiz, Garth T. Whiteside, Glen Apseloff, Stephen C. Harris   +6 more
wiley   +1 more source

Gender and Age Effects on the Trajectory of Depression in Opioid Users during Methadone Maintenance Treatment

Frontiers in Psychiatry, 2017
IntroductionBoth heroin use and depression are significant health problems. Methadone maintenance treatment (MMT) can be of great benefit to heroin users. However, changes in the level of depression in heroin users during MMT are not clear.
Peng-Wei Wang, Peng-Wei Wang, Huang-Chi Lin, Huang-Chi Lin, Yi-Hsin Connie Yang, Chih-Yao Hsu, Kuan-Sheng Chung, Hung-Chi Wu, Cheng-Fang Yen, Cheng-Fang Yen   +9 more
doaj   +1 more source