Results 41 to 50 of about 170,139 (366)
Reciprocal Substitution Between Methamphetamine and Heroin in Terms of Reinforcement Effects in Rats
Frontiers in Psychiatry, 2020 Heroin and methamphetamine are both popular illicit drugs in China. Previous clinical data showed that habitual users of either heroin or methamphetamine abuse the other drug for substitution in case of unavailability of their preferred drug. The present
Di-sen Mei +9 more
doaj +1 more source
Pathways to age of onset of heroin use: a structural model approach exploring the relationship of the COMT gene, impulsivity and childhood trauma. [PDF]
PLoS ONE, 2012 The interaction of the association of dopamine genes, impulsivity and childhood trauma with substance abuse remains unclear.To clarify the impacts and the interactions of the Catechol -O-methyltransferase (COMT) gene, impulsivity and childhood trauma on ...
Ting Li +8 more
doaj +1 more source
Heroin addiction hijacks the Nucleus Accumbens: craving and reactivity to naturalistic stimuli [PDF]
arXiv, 2021 Drug-related cues hijack attention away from alternative reinforcers in drug addiction, inducing craving and motivating drug-seeking. However, the neural correlates underlying this biased processing, its expression in the real-world, and its relationship to cue-induced craving are not fully established, especially in opioid addiction.
arxiv
Heroin maintenance for chronic heroin-dependent individuals [PDF]
Cochrane Database of Systematic Reviews, 2010 Several types of medications have been used for stabilizing heroin users: Methadone, Buprenorphine and levo-alpha-acetyl-methadol (LAAM.) The present review focuses on the prescription of heroin to heroin-dependent individuals.To compare heroin maintenance to methadone or other substitution treatments for opioid dependence regarding: efficacy and ...
Carlo A. Perucci +2 more
openaire +4 more sources
The OxyContin Reformulation Revisited: New Evidence From Improved Definitions of Markets and Substitutes [PDF]
arXiv, 2021 The opioid epidemic began with prescription pain relievers. In 2010 Purdue Pharma reformulated OxyContin to make it more difficult to abuse. OxyContin misuse fell dramatically, and concurrently heroin deaths began to rise. Previous research overlooked generic oxycodone and argued that the reformulation induced OxyContin users to switch directly to ...
arxiv
The newer opioid agonist treatment with lower substitutive opiate doses is associated with better toxicology outcome than the older harm reduction treatment [PDF]
, 2016 Background: Charge-free heroin use disorder treatment in Italy follows two main approaches, i.e., harm reduction treatment (HRT) strategy in community low-threshold facilities for drug addiction and opioid agonist treatment (OAT) in high-threshold ...
Bacciardi, Silvia +8 more
core +1 more source
Medicines legislation and regulation in the United Kingdom 1500‐2020
British Journal of Clinical Pharmacology, Volume 89, Issue 1, Page 80-92, January 2023., 2023 The initial purposes of regulation of medicines in England, and latterly in the United Kingdom, were principally to raise government revenue, to discourage murder by poisoning and to regulate the activities of pharmacists. It was only much later that regulators sought to ensure that medicines were of good quality, reasonably safe, and at least somewhat
Robin E. Ferner, Jeffrey K. Aronson
wiley +1 more source
Frontiers in Molecular Neuroscience, 2022 Reconsolidation of heroin-associated memory is an independent memory process that occurs following retrieval, which is essential for the sustained capacity of an associative drug stimulus to precipitate heroin-seeking.
Haoyu Li +17 more
doaj +1 more source
Should heroin be prescribed to heroin misusers? No [PDF]
BMJ, 2008 Prescribing heroin to heroin addicts is a strategy beloved by top police officers1 and successive home secretaries.2 It is a strategy, though, borne of utter frustration at our seeming inability to tackle an escalating drug problem. If you cannot stop addicts committing crimes to fund their drug habit then, so the argument goes, the next best thing is ...
openaire +3 more sources
Basic &Clinical Pharmacology &Toxicology, Volume 132, Issue 1, Page 111-119, January 2023., 2023 Abstract Information regarding deaths caused by poisoning or adverse effects of medication in Danish persons not using illicit narcotic drugs (PNUIDs) is sparse. To characterize aetiology, demographics, and death scene, we reviewed all legal autopsies performed at Aarhus University from 2017 to 2019 and isolated 96 deaths caused by medications in ...
Charlotte U. Andersen +4 more
wiley +1 more source