Results 41 to 50 of about 100,982 (338)

Association of Nonmedical Prescription Opioid Use With Subsequent Heroin Use Initiation in Adolescents.

JAMA pediatrics, 2019
Importance There is concern that nonmedical prescription opioid use is associated with an increased risk of later heroin use initiation in adolescents, but to our knowledge, longitudinal data addressing this topic are lacking.
Lorraine I. Kelley-Quon, Junhan Cho, D. Strong, R. Miech, J. Barrington-Trimis, Afton Kechter, A. Leventhal   +6 more
semanticscholar   +1 more source

Using a pragmatically adapted, low-cost contingency management intervention to promote heroin abstinence in individuals undergoing treatment for heroin use disorder in UK drug services (PRAISE): a cluster randomised trial

BMJ Open, 2021
Introduction Most individuals treated for heroin use disorder receive opioid agonist treatment (OAT)(methadone or buprenorphine). However, OAT is associated with high attrition and persistent, occasional heroin use.
Julian Mutz, Andrew Pickles, Sarah Byford, John Dunn, Kimberley Goldsmith, Franziska Mosler, Tim Weaver, James Shearer, Emily Finch, John Strang, Clare Davey, Stephen Pilling, Anthony Glasper, Nicola Metrebian, Jennifer Hellier, Luke Mitcheson, Prun Bijral, Nadine Bogdan, Owen Bowden-Jones, Edward Day, Sam Forshall, Shabana Akhtar, Jalpa Bajaria, Carmel Bennett, Elizabeth Bishop, Vikki Charles, Roopal Desai, Claire Goodfellow, Farjana Haque, Nicholas Little, Hortencia McKechnie, Jo Morris, Ruth Pauli, Dilkushi Poovendran, Elizabeth Phillips   +34 more
doaj   +1 more source

Gender and Age Effects on the Trajectory of Depression in Opioid Users during Methadone Maintenance Treatment

Frontiers in Psychiatry, 2017
IntroductionBoth heroin use and depression are significant health problems. Methadone maintenance treatment (MMT) can be of great benefit to heroin users. However, changes in the level of depression in heroin users during MMT are not clear.
Peng-Wei Wang, Peng-Wei Wang, Huang-Chi Lin, Huang-Chi Lin, Yi-Hsin Connie Yang, Chih-Yao Hsu, Kuan-Sheng Chung, Hung-Chi Wu, Cheng-Fang Yen, Cheng-Fang Yen   +9 more
doaj   +1 more source

Contribution of Addictovigilance data to assess adverse‐events linked to psychoactive substances in children and adolescents

British Journal of Clinical Pharmacology, EarlyView.
Aims We sought to characterize adverse events and deaths associated with the use of psychoactive substances in children and adolescents. Methods Two French Addictovigilance databases were analysed: spontaneous reports and deaths over the period 2016–2021, in subjects aged 10–<18 years. An unsupervised classification was implemented on consumption data (
Hélène Peyrière, Anne Batisse, Nathalie Fouilhé Sam‐Laï, Amélie Daveluy, Christine Fournier‐Choma, Sylvie Deheul, Cécile Chevalier, Clémence Lacroix, Valérie Gibaja, Aurélie Aquizerate, Stéphanie Pain, Emilie Jouanjus, Marie‐Christine Picot, Erika Nogue   +13 more
wiley   +1 more source

Trends in opioid prescribing in Scandinavian countries from 2010 to 2023: Insights from multi‐metric evaluation

British Journal of Clinical Pharmacology, EarlyView.
Aims Monitoring opioid prescribing across different healthcare systems is essential to understanding population‐level exposure and informing global health policies. This study examined opioid utilization in Scandinavian countries between 2010 and 2023 using multiple complementary metrics, addressing the limitations of single‐metric comparisons ...
Gabriela Rolová, Svetlana Skurtveit, Marte Handal, Geana Paula Kurita, Torgeir Gilje Lid, Ingvild Odsbu, Mikael Hoffmann   +6 more
wiley   +1 more source

Acute ovarian hormone treatment in freely cycling female rats regulates distinct aspects of heroin seeking

Learning & memory (Cold Spring Harbor, N.Y.), 2019
Females are at higher risk for certain opioid addictive behaviors, but the influence of ovarian hormones is unknown. In our rat model of heroin self-administration, females exhibited higher relapse rates that correlated with rates of heroin seeking on ...
Maribel Vazquez, Jessica H Frazier, C. Reichel, J. Peters   +3 more
semanticscholar   +1 more source

A Systematic Review of Substance Misuse Treatment Processes and Outcomes as Implemented in Prisons for Men in the UK

Criminal Behaviour and Mental Health, EarlyView.
ABSTRACT Background With a rising prison population, a substantial portion of whom are identified as substance misusers, it is important to understand the availability of treatment pathways, their successes and areas for improvement. Given the likely importance of national factors in criminal justice and substance use service provision, we chose to ...
Kim Barnett, Noor Butt, Rosie Allen, Pauline Goodlad, Anne Krayer, Adam O'Neill, Peter Huxley, Catherine Robinson, Emily Peckham, Rob Poole   +9 more
wiley   +1 more source

HCV and HIV infection among heroin addicts in methadone maintenance treatment (MMT) and not in MMT in Changsha and Wuhan, China. [PDF]

PLoS ONE, 2012
OBJECTIVE: To compare HCV and HIV infection among heroin addicts in MMT and not in MMT in two large cities in central China. METHODS: A total of 541 heroin addicts were recruited from MMT clinics and voluntary detoxification centers in Changsha and Wuhan,
Xuyi Wang, Linxiang Tan, Yi Li, Yao Zhang, Dongyi Zhou, Tieqiao Liu, Wei Hao   +6 more
doaj   +1 more source

Heroin addiction engages negative emotional learning brain circuits in rats.

Journal of Clinical Investigation, 2019
Opioid use disorder (OUD) is associated with the emergence of persistent negative emotional states during drug abstinence that drive compulsive drug taking and seeking.
Stephanie A. Carmack, R. Keeley, Janaina C. M. Vendruscolo, Emily G. Lowery-Gionta, Hanbing Lu, G. Koob, E. Stein, L. Vendruscolo   +7 more
semanticscholar   +1 more source

Speaking of Stigma: Piloting Language Training in Addiction Counseling Coursework

Counselor Education and Supervision, EarlyView.
ABSTRACT This pilot study examined counselor‐in‐training (CIT) attitudes and awareness regarding stigma and stigmatizing language aimed at those with substance use disorders before and after an author‐developed educational intervention. Results indicated this intervention positively impacted CIT awareness and attitudes and their ability to identify and
Amy L. Grybush, George Stoupas, Phillip B. Clarke   +2 more
wiley   +1 more source