Advances in Drug and Alcohol Research, 2023 Opioid misuse in the United States contributes to >70% of annual overdose deaths. To develop additional therapeutics that may prevent opioid misuse, further studies on the neurobiological consequences of opioid exposure are needed.
Mary Tresa Zanda +7 more
doaj +1 more source
, 2016 On the subject of narcotics, American public discourse is prone to alarmism, but it is not an exaggeration to say that the United States is currently experiencing an epidemic of opiate addiction.
Patrick Radden Keefe
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Diffusivity of the uncinate fasciculus in heroin users relates to their levels of anxiety [PDF]
, 2015 Heroin use is closely associated with emotional dysregulation, which may explain its high comorbidity with disorders such as anxiety and depression. However, the understanding of the neurobiological etiology of the association between heroin use and ...
Chan, CCH +6 more
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A multi-state model to estimate incidence of heroin use
BMC Medical Research Methodology, 2013 Background Existing incidence estimates of heroin use are usually based on one information source. This study aims to incorporate more sources to estimate heroin use incidence trends in Spain between 1971 and 2005.
Sánchez-Niubò Albert +5 more
doaj +1 more source
The Leeds Evaluation of Efficacy of Detoxification Study (LEEDS) project: An open-label pragmatic randomised control trial comparing the efficacy of differing therapeutic agents for primary care detoxification from either street heroin or methadone [ISRCTN07752728] [PDF]
, 2004 BACKGROUND: Heroin is a synthetic opioid with an extensive illicit market leading to large numbers of people becoming addicted. Heroin users often present to community treatment services requesting detoxification and in the UK various agents are used ...
A Ritter +22 more
core +3 more sources
EClinicalMedicine, 2019 Background: Heroin is currently contributing to the worst drug addiction epidemic in United States history; recent rates of use, dependence and death have also increased dramatically in parts of Europe.
Christina Marel +5 more
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Heroin withdrawal as a possible cause of acute concomitant esotropia in adults [PDF]
, 2001 Aim: To report the possible effects of heroin withdrawal on binocular vision. Methods: To present a case series of patients in whom esotropia developed on cessation of heroin use.
Firth, A.Y.
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No evidence of accelerated epigenetic aging among black heroin users: A case vs control analysis
Addiction Neuroscience, 2023 This study sought to assess the association between illicit opioid use and accelerated epigenetic aging (A.K.A. DNAm Age) among people of African ancestry who use heroin.
Jermaine D. Jones +4 more
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Serum proteomic analysis reveals high frequency of haptoglobin deficiency and elevated thyroxine level in heroin addicts. [PDF]
PLoS ONE, 2014 Heroin addiction is a chronic, complex disease, often accompanied by other concomitant disorders, which may encumber effective prevention and treatment. To explore the differences in expression profiles of serum proteins in control and heroin addicts, we
Bing-Ying Zhou +6 more
doaj +1 more source
A Review on Hematological Factors in Opioid-Dependent People (Opium and Heroin) after the Withdrawal Period [PDF]
Addiction and Health, 2010 Background: Long-term use of opioids has acute effects on homeostasis of the body. Discovering the impacts of opioids on hematological parameters of narcotics withdrawal and dependents blood may be helpful in recognizing the homeostasis condition
Tahereh Haghpanah +2 more
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