Results 51 to 60 of about 179,765 (329)

Contextualizing prescription opioid misuse and heroin use within dimensional models of drug involvement

open access: yesDrug and Alcohol Dependence Reports, 2022
Background: Prescription opioid misuse (POM) is often implicated in heroin initiation, despite evidence that POM does not predict heroin initiation any better than other drug use.
Genevieve F. Dash   +2 more
doaj   +1 more source

Itraconazole-induced Torsade de Pointes in a patient receiving methadone substitution therapy [PDF]

open access: yes, 2009
Issues. Methadone, a pharmacological agent used to treat heroin dependence is relatively safe, but may cause cardiac arrhythmias in the concurrent presence of other risk factors. Approach and Key Findings.
Narayanan, S.   +2 more
core  

Cold EI—The Way to Improve GC‐MS and Increase Its Range of Applications

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT Gas chromatography‐mass spectrometry (GC‐MS) with Cold electron ionization (EI) is based on interfacing the GC and MS with a supersonic molecular beam (SMB) along with electron ionization of vibrationally cold sample compounds in the SMB in a contact‐free fly‐through ion source (hence the name Cold EI).
Aviv Amirav   +3 more
wiley   +1 more source

MicroRNA-mediated translational pathways are regulated in the orbitofrontal cortex and peripheral blood samples during acute abstinence from heroin self-administration

open access: yesAdvances in Drug and Alcohol Research, 2023
Opioid misuse in the United States contributes to >70% of annual overdose deaths. To develop additional therapeutics that may prevent opioid misuse, further studies on the neurobiological consequences of opioid exposure are needed.
Mary Tresa Zanda   +7 more
doaj   +1 more source

Heroin Use and Prescription Drug Misuse in Kentucky [PDF]

open access: yes, 2016
The most recent Kentucky Health Issues Poll (KHIP) on heroin use and prescription drug misuse shows where our state's drug problems are hitting hardest. Northern Kentucky residents are twice as likely as other Kentucky residents to report knowing someone

core  

Early Life Stress Promotes Heroin Seeking But Does Not Alter the Excitability of Insular Pyramidal Cells Targeting the Nucleus Accumbens

open access: yesFrontiers in Behavioral Neuroscience, 2021
A number of retrospective studies have demonstrated adverse childhood experiences are associated with increased vulnerability to substance use disorders, including opioid use disorders (OUDs).
Jonna M. Leyrer-Jackson   +3 more
doaj   +1 more source

Intranasal diamorphine population pharmacokinetics modeling and simulation in pediatric breakthrough pain

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 435-447, March 2025.
Abstract Intranasal diamorphine (IND), approved for managing breakthrough pain in the UK, has been identified as an acceptable alternative offering effective, expedient, and less traumatic analgesia for children. However, the current dose regimen in pediatric populations relies on clinical expertise while the pharmacokinetics properties are poorly ...
Lianjin Cai   +6 more
wiley   +1 more source

A Review on Hematological Factors in Opioid-Dependent People (Opium and Heroin) after the Withdrawal Period [PDF]

open access: yesAddiction and Health, 2010
Background: Long-term use of opioids has acute effects on homeostasis of the body. Discovering the impacts of opioids on hematological parameters of narcotics withdrawal and dependents blood may be helpful in recognizing the homeostasis condition
Tahereh Haghpanah   +2 more
doaj  

A multi-state model to estimate incidence of heroin use

open access: yesBMC Medical Research Methodology, 2013
Background Existing incidence estimates of heroin use are usually based on one information source. This study aims to incorporate more sources to estimate heroin use incidence trends in Spain between 1971 and 2005.
Sánchez-Niubò Albert   +5 more
doaj   +1 more source

Racial and Ethnic Differences in the Effects of Prescription Drug Monitoring Program Laws on Overdose Deaths in the United States

open access: yesThe Milbank Quarterly, EarlyView.
Policy Points State “must‐query” prescription drug monitoring programs (PDMPs) were associated with increased overdose deaths, suggesting these policies may have unintended consequences. Black and Hispanic populations experienced disproportionately higher increases in overdose deaths following must‐query PDMP adoption, highlighting that these policies ...
SPRUHA JOSHI   +4 more
wiley   +1 more source

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