Results 61 to 70 of about 48,510 (233)

Repeated Episodes of Heroin Cause Enduring Alterations of Circadian Activity in Protracted Abstinence

Brain Sciences, 2012
Opiate withdrawal is followed by a protracted abstinence syndrome consisting of craving and physiological changes. However, few studies have been dedicated to both the characterization and understanding of these long-term alterations in post-dependent ...
Luis Stinus, Martine Cador, Stephanie Caille   +2 more
doaj   +1 more source

The psychoactive effects of repeated ketamine infusions and their mechanistic role in the treatment of alcohol use disorder: Secondary analysis of a randomised controlled trial

Addiction, EarlyView.
Abstract Background and aims Ketamine assisted psychotherapy is a promising new treatment for alcohol use disorder (AUD). The psychoactive effects of repeated intravenous (IV) ketamine infusions in people with AUD and their mechanistic role in treating AUD are largely unknown.
Cassie Bloy, Ananya Sarma, Bethan Marsh, Lorna Hardy, Meryem Grabski, Merve Mollaahmetoglu, Joshua Shotton, Shamhethan Bhaskaran, Anne Lingford‐Hughes, H. Val Curran, Celia Morgan, Will Lawn   +11 more
wiley   +1 more source

Hippocampal subfield differences in people with and without recreational ketamine use: Insights from multi‐modal neuroimaging

Addiction, EarlyView.
Abstract Background and aims Recreational ketamine use has increased globally and is associated with psychiatric and cognitive concerns. The hippocampus in preclinical models shows damage and working‐memory disruption with repeated dosing. However, whether specific hippocampal subregions may differ in people with chronic ketamine use remains unclear ...
Yi‐Hsuan Liu, Chia‐Chun Hung, Marc N. Potenza, Kun‐Hsien Chou, Pei‐Lin Lee, Chu‐Chung Huang, Chiang‐Shan R. Li, Tony Szu‐Hsien Lee, Ching‐Po Lin   +8 more
wiley   +1 more source

Pharmacological treatment strategies to manage precipitated withdrawal following the administration of buprenorphine in opioid use disorder: A systematic review

Addiction, EarlyView.
Abstract Background and aims There has been limited evidence synthesis examining the treatment of buprenorphine precipitated opioid withdrawal (BPOW). We aimed to conduct the first systematic review to assess the clinical utility of any pharmacological intervention in the management of BPOW.
Emmert Roberts, Nicola Kalk, John Strang
wiley   +1 more source

Detection of heroin metabolites at different developmental stages of Lucilia cuprina (Diptera: Calliphoridae) reared in heroin-treated meat: a preliminary analysis

Egyptian Journal of Forensic Sciences, 2019
Background Blowfly larvae and pupae collected during post-mortem forensic investigation can be analysed to detect drugs or toxins in a dead body. Drug or toxin-contaminated tissues of human remains consumed by blowfly larvae are stored in the crop even ...
Nooratiny Ishak, Abu Hassan Ahmad, Siti Azizah Mohamad Noor, Azwandi Ahmad   +3 more
doaj   +1 more source

The Polysubstance Assessment Tool: Reliability, acceptability and feasibility of a novel measure of polysubstance use

Addiction, EarlyView.
Abstract Background and aims There are currently no brief quantitative assessments that capture the drug patterns of people who engage in use of more than one drug on the same day or simultaneously. The current study examined the retest reliability, acceptability and feasibility of a new quantitative assessment to measure polysubstance use.
Amanda M. Bunting, Charles M. Cleland, S. Michaela Barratt, Brittany Griffin, Jaimee Williams, Carrie B. Oser, Joshua D. Lee, Jennifer McNeely   +7 more
wiley   +1 more source

Exploring the intersection of heavy alcohol use and masculine norms as risk factors for male‐to‐female intimate partner violence: Evidence from an Australian national survey

Addiction, EarlyView.
Abstract Background and aims Endorsement of traditional masculine norms and male alcohol use are identified risk factors for male‐to‐female intimate partner violence (MFIPV) perpetration, yet their interaction remains unexplored in Australia. This study aimed to estimate the associations between heavy male alcohol use, endorsement of traditional ...
Bree Willoughby, Koen Smit, Ingrid M. Wilson, Gail Gilchrist, Anne‐Marie Laslett   +4 more
wiley   +1 more source

Correction to: Hostility, compassion and role reversal in West Virginia’s long opioid overdose emergency

Harm Reduction Journal, 2021
Jeff Ondocsin, Sarah G. Mars, Mary Howe, Daniel Ciccarone   +3 more
doaj   +1 more source

Theorizing causality: A qualitative study of xylazine‐related wound diversity and perceived etiology among people who inject drugs

Addiction, EarlyView.
Abstract Background and aims Incidence and severity of opioid‐associated skin and soft‐tissue infections, often requiring intensive and costly medical care, have increased substantially since the emergence of xylazine in the US drug supply. Although progress has been made in clinical and harm reduction recommendations for treating xylazine‐related ...
Danielle German, Kelci Villarroel, Meredith Denney, Adrian Guta, Julie Evans, Jason Bienert, Alex Fidler, Kim Ashburn, Zach Kosinski, Becky L. Genberg   +9 more
wiley   +1 more source

Historical trends in self‐reported US heroin initiation

Addiction, EarlyView.
Abstract Background and aims Illegal opioids create challenges for public health and safety. There is imperfect understanding of when use of illegally manufactured opioids increased. This paper examined data on self‐reported year of first heroin use in the United States. Design Secondary analysis of general population survey data. Setting United States.
Jonathan P. Caulkins, Bishu Giri
wiley   +1 more source