Results 71 to 80 of about 100,982 (338)

Beyond the numbers: Critical analysis of the role of postmortem tryptase in the forensic diagnosis of anaphylaxis

Journal of Forensic Sciences, EarlyView.
Abstract The postmortem diagnosis of anaphylaxis remains a forensic challenge due to the lack of specific external signs. Tryptase, a mast cell‐derived protease, has emerged as a potential biomarker for fatal anaphylaxis. This systematic review critically examined 40 studies published between 2014 and 2024, including both biochemical and ...
Luca Tomassini, Giulia Ricchezze, Cristiana Gambelunghe, Massimo Lancia, Marco Gramaccia, Francesco De Micco, Piergiorgio Fedeli, Mariano Cingolani, Roberto Scendoni   +8 more
wiley   +1 more source

Individual Vulnerability to Stress Is Associated With Increased Demand for Intravenous Heroin Self-administration in Rats

Frontiers in Behavioral Neuroscience, 2019
Opioid use is a widespread epidemic, and traumatic stress exposure is a critical risk factor in opioid use and relapse. There is a significant gap in our understanding of how stress contributes to heroin use, and there are limited studies investigating ...
Nathaniel P. Stafford, Theodore N. Kazan, Colleen M. Donovan, Erin E. Hart, Robert C. Drugan, Sergios Charntikov   +5 more
doaj   +1 more source

Drug‐facilitated crime: A review of findings between 2019 and 2023

Journal of Forensic Sciences, EarlyView.
Abstract Drug‐facilitated crime (DFC) is a criminal act (e.g., assault, robbery, or sexual assault) in which the perpetrator uses drugs to impair the victim's ability to resist, remember, or recognize the crime being committed. Ethanol is commonly implicated in DFC casework, but limited data are published on other substances currently implicated in ...
Meaghan R. Hessler, Sherri L. Kacinko, Barry K. Logan   +2 more
wiley   +1 more source

A model of ethanol self‐administration in head‐fixed mice

Alcohol, Clinical and Experimental Research, EarlyView.
Advances in neuroscience allow unparalleled access to the brain through multiphoton microscopy, high‐density electrodes, and widefield imaging; however, these techniques often require head fixation. Here, we show head‐fixed mice learn to self‐administer alcohol, extinguish lever‐press responding, and reinstate alcohol seeking to both alcohol and an ...
Amy L. Ward, Kion T. Winston, Sophie Buchmaier, Cynara J. Cooper, Rachel E. Clarke, Michael R. Martino, Kelsey M. Vollmer, Jacqueline E. Paniccia, Marcus S. Bell, Elizabeth M. Doncheck, Roger I. Grant, Joshua Boquiren, Jade Baek, Logan M. Manusky, Annaka M. Westphal, Lisa M. Green, Bayleigh E. Pagoota, James M. Otis, Jennifer A. Rinker   +18 more
wiley   +1 more source

Does Chinese culture influence psychosocial factors for heroin use among young adolescents in China? A cross-sectional study

BMC Public Health, 2010
Background Little empirical research has examined how cultural factors influence psychosocial factors for heroin drug use. The objectives of the study were to investigate the levels of individualism and collectivism among young adolescents and how ...
Liu Wei, Lu Zhouping, Li Jian, Liu Hongjie, Zhang Zhiyong   +4 more
doaj   +1 more source

Experiences and barriers to alcohol use disorder treatment among adults with and without self‐reported executive functioning challenges: A mixed‐methods study

Alcohol, Clinical and Experimental Research, EarlyView.
Participants described several challenges seeking treatment for alcohol use disorder (AUD), including multiple prior treatment attempts, delayed recognition of problematic alcohol use, and incongruent treatment expectations and experiences. Those with executive functioning challenges (53%) described the need to self‐advocate and frustration with ...
Cayley Russell, Jessica L. Wiese, Anthony C. Ruocco, Nikki Bozinoff, Raul Gonzalez, Sheila Jennings, Marco Leyton, Yuliya S. Nikolova, Josh Orson, Marc N. Potenza, Lena C. Quilty, Kevin D. Shield, Antonio Verdejo‐Garcia, Samantha Wells, Shannon Lange, The CDiA Program Study Group, Etienne Sibille, Daniel Felsky, Thomas Prevot, Yuliya Nikolova, Jeffrey Wardell, Erica Vieira, Daphne Voineskos, Isabelle Boileau, Daniel Blumberg, Christopher Bowie, Paul Fletcher, Phil Gerretsen, Ahmed Hassan, Colin Hawco, Yarissa Herman, Pamela Kaduri, Bernard Le Foll, Osnat Melamed, Leanne Quigley, Jürgen Rehm, Kevin Shield, Matthew Sloan, Victor Tang, Wei Wang   +39 more
wiley   +1 more source

Repeated Episodes of Heroin Cause Enduring Alterations of Circadian Activity in Protracted Abstinence

Brain Sciences, 2012
Opiate withdrawal is followed by a protracted abstinence syndrome consisting of craving and physiological changes. However, few studies have been dedicated to both the characterization and understanding of these long-term alterations in post-dependent ...
Luis Stinus, Martine Cador, Stephanie Caille   +2 more
doaj   +1 more source

DNA Methylation Profiling of Human Prefrontal Cortex Neurons in Heroin Users Shows Significant Difference between Genomic Contexts of Hyper- and Hypomethylation and a Younger Epigenetic Age

Genes, 2017
We employed Illumina 450 K Infinium microarrays to profile DNA methylation (DNAm) in neuronal nuclei separated by fluorescence-activated sorting from the postmortem orbitofrontal cortex (OFC) of heroin users who died from heroin overdose (N = 37 ...
A. Kozlenkov, A. Jaffe, Alisa Timashpolsky, Pasha Apontes, S. Rudchenko, Mihaela Barbu, W. Byne, Y. Hurd, S. Horvath, S. Dracheva   +9 more
semanticscholar   +1 more source

Trajectories of medication for opioid use disorder and their impact on HIV testing among people who inject drugs in India: A longitudinal assessment of clinic‐based data

Addiction, Volume 120, Issue 4, Page 745-755, April 2025.
Abstract Aims The aim of this study was to identify longitudinal trajectories of medication for opioid use disorder (MOUD) use throughout 1 year following MOUD initiation and to examine the association of trajectory membership with HIV testing among people who inject drugs in India.
Allison M. McFall, Lakshmi Ganapathi, Mihili P. Gunaratne, Aylur K. Srikrishnan, Conjeevaram K. Vasudevan, Santhanam Anand, Sunil S. Solomon, Shruti H. Mehta, Gregory M. Lucas   +8 more
wiley   +1 more source

Psychedelic‐assisted treatment for substance use disorder: A narrative systematic review

Addiction, EarlyView.
Abstract Background and aims This is the first systematic review of the extant literature on all major psychedelic‐assisted treatment for alcohol use disorder (AUD), tobacco use disorder (TUD) and other substance use disorders (SUD). We aimed to summarise the evidence for efficacy of psychedelic‐assisted treatment for AUD, TUD, and SUD; to evaluate its
Theodore Piper, Francesca Small, Sam Brown, Michael Kelleher, Luke Mitcheson, James Rucker, Allan H. Young, John Marsden   +7 more
wiley   +1 more source