Results 41 to 50 of about 62,557 (287)

Harm reduction among injecting drug users - evidence of effectiveness [PDF]

, 2010
This chapter synthesises and evaluates the available direct evidence relating to the impact of needle and syringe programmes (NSPs), opioid substitution treatment (OST), drug consumption rooms (DCRs), and peer naloxone distribution (PND) on HIV/hepatitis
Goldberg, David, Hickman, Matthew, Hutchinson, Sharon, Kimber, Jo, Palmateer, Norah, Rhodes, Tim   +5 more
core   +1 more source

Buprenorphine added on brief cognitive behavioral therapy for treatment of methamphetamine use disorder [PDF]

, 2018
Background: Methamphetamine (MA) use remains a major public health concern around the world. Recent findings suggest that buprenorphine may be helpful for cocaine use reduction. Moreover, animal studies described reduced dopamine peak effect following MA
Dean AJ, Hassani-Abharian P, Hollister LE, Karimlou M, Kirchmayer U, Kosten TR, Mello NK, Nejati V, Raistrick D, Rothenberg JL,     +10 more
core   +1 more source

Neurobehavioral consequences of chronic intrauterine opioid exposure in infants and preschool children: a systematic review and meta-analysis [PDF]

, 2014
<b>Background</b><p></p> It is assumed within the accumulated literature that children born of pregnant opioid dependent mothers have impaired neurobehavioral function as a consequence of chronic intrauterine opioid use.<p>&
A Baldacchino, A Liberati, A Ornoy, A Sameroff, A Verdejo-Garcia, AJ Dunlop, Alex Baldacchino, American Psychiatric Association, B Hanson, BJ Cleary, Britannica, C Konijnenberg, C Konijnenberg, Colin McCowan, DE Hutchings, Dennis J Petrie, Department of Health (England) and the devolved administrations, DF Stroup, E Rotheram-Fuller, E Strauss, EK Emory, FM Wolf, GJ Demakis, H Cooper, HC Steinhausen, HE Jones, HE Jones, I Fihrer, I van Beusekom, IM Bernstein, J Cohen, J Cohen, J Keegan, J Kimber, J Prosser, JE Hunter, JN Whitham, JP Higgins, K Spiteri Cornish, Kathleen Arbuckle, KB Walhovd, KD Ersche, KK Zakzanis, L Manchikanti, L McGlone, LV Hedges, LV Hedges, LW Anderson, M Borenstein, M Borenstein, M Connock, M Farrell, M Grattan, M Pirastu, MD Lezak, MM de Cubas, National Collaborating Centre for Methods and Tools, NICE, NICHD, PS Bauman, R Bunikowski, R Cornish, R Hamilton, R King, RE Johnson, RG Orwin, RJ Sternberg, RW Hunt, S Darke, S Minozzi, S Salo, S Simeons, S Soepatmi, S Tong, Scottish Government, SL Grace, SL Hans, SL Hans, SM Petterson, SM Quinhana, SR Kandall, TB Huedo-Medina, TJ Ornstein, TS Rosen, V Moe, WH Organization, WK Lombardo   +86 more
core   +12 more sources

The Leeds Evaluation of Efficacy of Detoxification Study (LEEDS) project: An open-label pragmatic randomised control trial comparing the efficacy of differing therapeutic agents for primary care detoxification from either street heroin or methadone [ISRCTN07752728] [PDF]

, 2004
BACKGROUND: Heroin is a synthetic opioid with an extensive illicit market leading to large numbers of people becoming addicted. Heroin users often present to community treatment services requesting detoxification and in the UK various agents are used ...
A Ritter, Advisory Council on the Misuse of Drugs, AH Masson, AK Nigam, Charlotte NE Tompkins, Clive E Adams, E Goddard, Great Britain Department of Health, Great Britain Government Statistical Service, Home Office, J Lowinson, J Strang, J Strang, L San, Laura Sheard, LJ Cheskin, M Ramsay, N Linteris, N Seivewright, Nat MJ Wright, Nicola S Oldham, PG O'Connor, Royal Pharmaceutical Society of Great Britain, WK Bickel   +22 more
core   +3 more sources

Evaluation of the Association of Htr2a Gene Rs6313 Polymorphism with Heroin Dependence in a Sample from Northwest Iran

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Īlām, 2021
Introduction: Heroin dependence is a chronic relapsing disorder caused by a combination of genetic, epigenetic, and environmental factors. The genetic contribution in the vulnerability to heroin dependence is 40%-60%. Alterations in dopamine transport in
Fatemeh Mahmoudi, Leila Mehdizadeh fanid, Narges Zeinalzadeh, Mohammad ali Hosseinpour feizy   +3 more
doaj  

The Chinese version of obsessive compulsive drug use scale: validation in outpatient methadone maintenance treatment program

BMC Psychiatry, 2020
Background The Obsessive Compulsive Drug Use Scale (OCDUS) measures the overall craving level within a period from a multidimensional perspective. However, no studies have addressed the validity of the new OCDUS factor structure, presented in 2016, in ...
Hengfen Gong, Yingying Zhang, Qihuan Ren, Zhirong Zhou, Huijing Zhou, Xirong Sun, Chencheng Zhang, Valerie Voon, Min Zhao, Shunying Yu   +9 more
doaj   +1 more source

Effects of Psychopathy on Neurocognitive Domains of Impulsivity in Abstinent Opiate and Stimulant Users

Frontiers in Psychiatry, 2021
Background: Psychopathy and substance use disorders (SUDs) are both characterized by neurocognitive impairments reflecting higher levels of impulsivity such as reward-driven decision-making and deficient inhibitory control.
Elena Psederska, Elena Psederska, Nicholas D. Thomson, Nicholas D. Thomson, Kiril Bozgunov, Dimitar Nedelchev, Georgi Vasilev, Jasmin Vassileva, Jasmin Vassileva   +8 more
doaj   +1 more source

Frontal Metabolite Concentration Deficits in Opiate Dependence Relate to Substance Use, Cognition, and Self-Regulation. [PDF]

, 2016
ObjectiveProton magnetic resonance spectroscopy (1H MRS) in opiate dependence showed abnormalities in neuronal viability and glutamate concentration in the anterior cingulate cortex (ACC).
Abé, Christoph, Durazzo, Timothy C, Guydish, Joseph, Meyerhoff, Dieter J, Murray, Donna E, Schmidt, Thomas P   +5 more
core   +1 more source

Lack of Association between Human µ-Opioid Receptor (OPRM1) Gene Polymorphisms and Heroin Addiction in A Sample of Southeast Iranian Population

AIMS Medical Science, 2017
It has been proposed that genetic factors account for 30%–50% of the risk for cocaine and heroin addiction. The present study was aimed to find out the impact of µ-opioid receptor gene (OPRM1) rs1799971 A > G and rs9479757 polymorphisms on heroin ...
Mansour Shakiba, Mohammad Hashemi, Zahra Rahbari, Salah Mahdar, Hiva Danesh, Fatemeh Bizhani, Gholamreza Bahari   +6 more
doaj   +1 more source

Reduction in cerebral perfusion after heroin administration: a resting state arterial spin labeling study. [PDF]

PLoS ONE, 2013
Heroin dependence is a chronic relapsing brain disorder, characterized by the compulsion to seek and use heroin. Heroin itself has a strong potential to produce subjective experiences characterized by intense euphoria, relaxation and release from craving.
Niklaus Denier, Hana Gerber, Marc Vogel, Markus Klarhöfer, Anita Riecher-Rossler, Gerhard A Wiesbeck, Undine E Lang, Stefan Borgwardt, Marc Walter   +8 more
doaj   +1 more source