Pathological regional blood flow in opiate-dependent patients during withdrawal: A HMPAO-SPECT study [PDF]
The aims of the present study were to investigate regional cerebral blood flow (rCBF) in heroin-dependent patients during withdrawal and to assess the relation between these changes and duration of heroin consumption and withdrawal data.
Biersack, H. J.+9 more
core +1 more source
Medical diagnoses associated with substance dependence among inpatients at a large urban hospital. [PDF]
There are limited data on reasons for hospital admission among patients dependent on substances other than alcohol. We compared primary discharge diagnoses for heroin- or cocaine-dependent patients to non-dependent patients.We evaluated a cohort of ...
Humberto Choi+3 more
doaj +1 more source
Enlarged cerebrospinal fluid spaces in opiate-dependent male patients: A stereological CT study [PDF]
Computed tomography was performed in 9 male patients with a diagnosis of opiate dependence and in 9 age-matched psychiatric controls (neurotic depression).
Broich, Karl+7 more
core +1 more source
The Leeds Evaluation of Efficacy of Detoxification Study (LEEDS) project: An open-label pragmatic randomised control trial comparing the efficacy of differing therapeutic agents for primary care detoxification from either street heroin or methadone [ISRCTN07752728] [PDF]
BACKGROUND: Heroin is a synthetic opioid with an extensive illicit market leading to large numbers of people becoming addicted. Heroin users often present to community treatment services requesting detoxification and in the UK various agents are used ...
A Ritter+22 more
core +3 more sources
Identifying and preventing health problems among young drug-misusing offenders [PDF]
Purpose – The purpose of this paper is to identify the health problems and treatment needs of drug-misusing offenders and to draw out the implications of the findings for health education and prevention.
Judith Aldridge+2 more
core +2 more sources
Treatment of heroin dependence with ibogaine
BackgroundThe use of the hallucinogen ibogaine as an anti-addiction agent has been described in several case reports, dating back to the eighties. The anti-addiction properties of ibogaine have been confirmed in a large body of animal work. Ibogaine has been shown to be effective in reducing withdrawal severity and substance use for a variety of ...
Schellekens, A.F.A.+4 more
openaire +3 more sources
Assessing the 2004-2018 fentanyl misusing issues reported to an international range of adverse reporting systems [PDF]
© 2019 Schifano, Chiappini, Corkery and Guirguis. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY).
Chiappini, Stephania+3 more
core +4 more sources
Frontal Metabolite Concentration Deficits in Opiate Dependence Relate to Substance Use, Cognition, and Self-Regulation. [PDF]
ObjectiveProton magnetic resonance spectroscopy (1H MRS) in opiate dependence showed abnormalities in neuronal viability and glutamate concentration in the anterior cingulate cortex (ACC).
Abé, Christoph+5 more
core +1 more source
Introduction: Heroin dependence is a chronic relapsing disorder caused by a combination of genetic, epigenetic, and environmental factors. The genetic contribution in the vulnerability to heroin dependence is 40%-60%. Alterations in dopamine transport in
Fatemeh Mahmoudi+3 more
doaj
It has been proposed that genetic factors account for 30%–50% of the risk for cocaine and heroin addiction. The present study was aimed to find out the impact of µ-opioid receptor gene (OPRM1) rs1799971 A > G and rs9479757 polymorphisms on heroin ...
Mansour Shakiba+6 more
doaj +1 more source