Results 91 to 100 of about 418,528 (398)
The Neglected Role of GSDMD C‐Terminal in Counteracting Type I Interferon Signaling
Advanced Science, EarlyView.The C‐terminal domain of Gasdermin D (GSDMD‐CT) shows functions beyond pyroptosis. GSDMD‐CT negatively regulates IFN‐I signaling during viral infection by triggering autophagic degradation of RIG‐I and TBK1. GSDMD‐CT interacts with retinoic acid‐inducible gene‐I (RIG‐I) and tank‐binding kinase 1 (TBK1), leading to TRIM28‐mediated ubiquitination and ...
Weilv Xu +17 more
wiley +1 more source
Time trends in herpesvirus seroepidemiology among Swedish adults
BMC Infectious DiseasesBackground Human herpesviruses are widespread among the human population. The infections often occur unnoticed, but severe disease as well as long-term sequelae are part of the symptom spectrum.
Jan Olsson +7 more
doaj +1 more source
Advanced Science, EarlyView.Ubiquitin‐mediated selective autophagy plays a critical role in antiviral innate immunity. The study shows that upon RNA virus infection, cytoplasmic API5 undergoes SRPK1‐dependent phosphorylation at S464, which in turn suppresses p62 K141 ubiquitination‐dependent autophagy.
Tingjuan Deng +10 more
wiley +1 more source
Acta Medica, 2004 Herpes simplex encephalitis is a rare complication of Herpes virus infections. Innate immune mechanisms are the first line of defence encountered by invading infectious agents.
Ayşe Tunca, Nüket Bavbek
doaj +1 more source
Medical Microbiology and Immmunology, 2014 Infection with herpes simplex viruses is one of the most ancient diseases described to affect humans. Infection with these viruses produces vexing effects to the host, which frequently recur.
Paula A. Suazo +3 more
semanticscholar +1 more source
A 3D human brain–like tissue model of herpes-induced Alzheimer’s disease
Science Advances, 2020 In vitro 3D human brain–like cultures infected with herpes virus develop Alzheimer’s disease characteristics. Alzheimer’s disease (AD) is a neurodegenerative disorder that causes cognitive decline, memory loss, and inability to perform everyday functions.
Dana M. Cairns +5 more
semanticscholar +1 more source
HSV-1 not only in human vestibular ganglia but also in the vestibular labyrinth [PDF]
, 2001 Reactivation of herpes simplex virus type 1 (HSV-1) in the vestibular ganglion (VG) is the suspected cause of vestibular neuritis (VN). Recent studies reported the presence of HSV-1 DNA not only in human VGs but also in vestibular nuclei, a finding that ...
Arbusow, Viktor +4 more
core +1 more source
Hologenomics Reveals Specialized Dietary Adaptations in the Mengla Snail‐Eating Snake
Advanced Science, EarlyView.Dietary adaptation studies from a holobiome perspective are scarce beyond mammals. This research reveals how genomic and microbial interactions drive dietary specialization in the Mengla snail‐eating snake, with evidence of gut symbiont convergence between reptiles and mammals.
Chaochao Yan +10 more
wiley +1 more source
The impact of herpes simplex virus on the cornea engraftment
Трансплантология (Москва), 2020 According to the recent WHO data, 39 million people in the world are blind. In developing countries cornea diseases are the second most common cause of blindness. Cornea transplantation remains the only radical method to regain lost vision for many blind
S. A. Borzenok +5 more
doaj +1 more source
Herpes Simplex virus meningitis in children in South East of Caspian Sea, Iran [PDF]
, 2014 Background: Herpes simplex virus (HSV) is a member of Herpesviridae and a leading cause of human viral diseases. Meningitis occurs as a complication of HSV-1 or HSV-2 primary infection.
Azadfar, S. +4 more
core +1 more source