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Ribonucleotide reductase of herpes simplex virus type 2 resembles that of herpes simplex virus type 1

Journal of Virology, 1984
The ribonucleotide reductase (ribonucleoside-diphosphate reductase; EC 1.17.4.1) induced by herpes simplex virus type 2 infection of serum-starved BHK-21 cells was purified to provide a preparation practically free of both eucaryotic ribonucleotide reductase and contaminating enzymes that could significantly deplete the substrates.
D R, Averett, P A, Furman, T, Spector
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Herpes simplex virus type 1 and Alzheimer’s disease

Neurobiology of Aging, 1999
Until recently, the only risk factors implicated in noninherited cases of Alzheimer's disease were increasing age, Down's syndrome, and probably, head injury. Having found that herpes simplex type 1 virus (HSV1) is present in the brain of many elderly people, we discovered that it is a risk factor for Alzheimer's disease when in the central nervous ...
Dobson, CB; id_orcid 0000-0002-6483-4608   +1 more
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Congenital Infection with Herpes Simplex Virus Type 1

Pediatric Dermatology, 1987
Abstract: We treated a newborn who had congenital herpes simplex virus (HSV) type 1 infection in which extensive skin lesions occurred with no evidence of involvement of other ograns. The correct diagnosis was not made until the fifth day of life, but after effective treatment with intravenous acyclovir this child has remained in perfect health.
M T, Glover, D J, Atherton
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Herpes simplex virus type 1 replication and recombination

Biochimie, 1995
Herpesviruses are a very interesting model for studying DNA replication in eukaryotic systems since they encode most of the proteins required for this process. These include a protein that specifically binds to the virus origin of DNA synthesis, a single-stranded DNA binding protein, an heterotrimeric helicase-primase and an heterodimeric DNA ...
D, Bataille, A L, Epstein
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Shedding of herpes simplex virus Type 1 into saliva

Journal of Oral Pathology & Medicine, 1988
The shedding of herpes simplex virus Type 1 (HSV‐1) into saliva was studied in 110 healthy individuals, 55 patients who were undergoing oral surgery, and 21 immunocompromised patients in an asymptomatic Japanese population. Specimens were collected regularly for up to 2 months from each individual. Virus was recovered on at least one occasion from 4.5%
T, Kameyama   +4 more
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Herpes simplex encephalitis: an autopsy case with isolation of type 1 herpes simplex virus

Acta Neuropathologica, 1977
An adult case of herpes simplex encephalitis was studied after autopsy. Postmortem examination revealed necrotizing encephalitis associated with Cowdry type A intranuclear inclusion bodies in glial cells. Herper simplex virus type 1 was isolated from the removed brain.
S, Miyake   +5 more
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[Herpes simplex virus type 1 and 2].

Nihon rinsho. Japanese journal of clinical medicine, 2010
Traditionally, herpes simplex virus (HSV) central nervous system infections have been diagnosed by inoculation of cell culture with brain biopsy material. In more recent times however, PCR detection of HSV in CSF has become the ‘gold standard’ for diagnosis of HSV encephalitis [3]. Occasionally, in cases of retrospective or neonate infections, serology
Neisha Jeoffreys, David M. Whiley
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Herpes Simplex Virus Type 1 in Alzheimer's Disease: The Enemy Within

Journal of Alzheimer's Disease, 2008
Alzheimer's disease is a modern scourge and is likely to become increasingly so in the future, with increasing longevity. The disease has been investigated for over one hundred years yet its causes and that of the neuropathological characteristics seen in AD brain are still completely unknown.
Itzhaki, Ruth F, Wozniak, Matthew
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Seroprevalence of herpes simplex virus type 1 and type 2 in Turkey

Journal of the European Academy of Dermatology and Venereology, 2006
AbstractBackground  Herpes simplex virus (HSV) infections are among the most common infectious diseases in humans. The prevalence of herpes simplex viruses type 1 (HSV‐1) and type 2 (HSV‐2) varies widely across the world. HSV‐2 infection is the primary cause of genital herpes.
Dolar, N.   +3 more
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Resistance to Herpes Simplex Virus — Type 1 (HSV-1)

1981
In man herpes simplex virus-type 1 (HSV-1) has been shown to be the cause of several clinically important infections, including primary gingivostomatitis, herpes keratitis, and encephalitis (Nahmias and Roizman 1973; Rawls 1973). Clinically apparent as well as inapparent infections with HSV-1 have the capacity to become latent, i.e., the virus remains ...
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