Results 71 to 80 of about 2,028,368 (401)

Nanomaterial‐Based Optical Biosensors for SARS‐CoV‐2 Detection: A Retrospective of the Pandemic

open access: yesAdvanced Sensor Research, EarlyView.
This review discusses nanomaterial‐based optical biosensors developed for or adapted to the detection of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2). It concludes by providing a perspective on how lessons learned during the coronavirus disease of 2019 (COVID‐19) pandemic may be applied for future research on nanomaterial‐based ...
Flavie Martin   +2 more
wiley   +1 more source

A Randomized Double-Blind Placebo Controlled Trial of Oral Acyclovir in Renal Allograft Recipients

open access: yesCanadian Journal of Infectious Diseases, 1993
Fifty renal transplant patients were randomized to receive either 800 mg acyclovir by mouth four times daily or identical placebo tablets for prophylaxis of herpes simplex infection. Patients were followed weekly to assess reactivation of herpes simplex,
Walter F Schlech   +5 more
doaj   +1 more source

Herpes hipertrófico perianal tratado eficazmente com imiquimod Hypertrophic perianal herpes successfully treated with imiquimod

open access: yesAnais Brasileiros de Dermatologia, 2011
A infecção pelo vírus herpes simples tipo 2 (HSV-2) é frequente em pacientes infetados pelo vírus de imunodeficiência adquirida (VIH). Nestes casos, o herpes genital pode ter uma apresentação clínica atípica.
Sara Isabel Alcântara Lestre   +3 more
doaj   +1 more source

Expression of the murine cytomegalovirus glycoprotein H by recombinant vaccinia virus [PDF]

open access: yes, 1994
The sequence of the gene encoding glycoprotein H (gH) of murine cytomegalovirus (MCMV) strain Smith was determined and compared with the sequence of the gH of MCMV strain K181. Transcriptional analysis showed that gH is encoded by a large mRNA of 5.0 kb,
Koszinowski, Ulrich H.   +4 more
core   +1 more source

Diagnosis of genital herpes simplex virus infection in the clinical laboratory

open access: yesVirology Journal, 2014
Since the type of herpes simplex virus (HSV) infection affects prognosis and subsequent counseling, type-specific testing to distinguish HSV-1 from HSV-2 is always recommended.
J. Legoff, H. Péré, L. Bélec
semanticscholar   +1 more source

Optogenetic‐Controlled iPSC‐Based Vaccines for Prophylactic and Therapeutic Tumor Suppression in Mice

open access: yesAdvanced Science, EarlyView.
This study develops an a red/far‐red light‐controlled iPSC‐based vaccines (RIVA) based on the chimeric photosensory protein FnBphP and its interaction partner LDB3 for cancer immunotherapy. The RIVA preserves the multiple intrinsic tumor antigens of iPSCs and enables optogenetic control of the expression of the immune adjuvant type I interferon β under
Longliang Qiao   +17 more
wiley   +1 more source

HSV-1 not only in human vestibular ganglia but also in the vestibular labyrinth [PDF]

open access: yes, 2001
Reactivation of herpes simplex virus type 1 (HSV-1) in the vestibular ganglion (VG) is the suspected cause of vestibular neuritis (VN). Recent studies reported the presence of HSV-1 DNA not only in human VGs but also in vestibular nuclei, a finding that ...
Arbusow, Viktor   +4 more
core   +1 more source

A 3D human brain–like tissue model of herpes-induced Alzheimer’s disease

open access: yesScience Advances, 2020
In vitro 3D human brain–like cultures infected with herpes virus develop Alzheimer’s disease characteristics. Alzheimer’s disease (AD) is a neurodegenerative disorder that causes cognitive decline, memory loss, and inability to perform everyday functions.
Dana M. Cairns   +5 more
semanticscholar   +1 more source

Hexokinase‐2 as a Therapeutic Target: Alleviating Herpes Simplex Keratitis Through Metabolic Reprogramming

open access: yesAdvanced Science, EarlyView.
Herpes Simplex Virus Type 1 (HSV‐1) infection triggers metabolic reprogramming in corneal cells, shifting from mitochondrial respiration to aerobic glycolysis with marked upregulation of Hexokinase‐2 (HK2). This study identifies HK2 as a therapeutic target: inhibiting HK2 with lonidamine significantly reduces viral replication and promotes corneal ...
Dan Jiang   +9 more
wiley   +1 more source

Molecular mimicry, genetic homology, and gene sharing proteomic “molecular fingerprints” using an EBV (Epstein-Barr virus)-derived microarray as a potential diagnostic method in autoimmune disease [PDF]

open access: yes, 2018
EBV (Epstein-Barr Virus) and other human DNA viruses are associated with autoimmune syndromes in epidemiologic studies. In this work, immunoglobulin G response to EBV-encoded proteins which share regions with human immune response proteins from the human
Alessandra Farina, Giuseppina   +2 more
core   +1 more source

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