Results 51 to 60 of about 17,666 (176)

Human Herpesviruses-encoded dUTPases: A Family of Proteins that Modulate Dendritic Cell Function and Innate Immunity

open access: yesFrontiers in Microbiology, 2014
We have previously shown that Epstein-Barr virus (EBV)-encoded dUTPase can modulate innate immune responses through the activation of TLR2 and NF-kappaB signaling. However, whether this novel immune function of the dUTPase is specific for EBV or a common
Maria Eugenia eAriza   +2 more
doaj   +1 more source

The Role of Viral and Bacterial Infections in the Etiology of Behçet's Disease

open access: yesJournal of Clinical Laboratory Analysis, Volume 40, Issue 1, January 2026.
Bacterial and viral pathogens may play a key role in Behçet's disease (BD) pathogenesis by triggering autoimmunity, molecular mimicry, or microbiome disruption. These infectious agents could initiate inflammatory pathways, contributing to BD's diverse clinical manifestations.
Mohsen Moghoofei   +4 more
wiley   +1 more source

Herpetic infections in humans: modern approaches to etiopathogenetic therapy

open access: yesЛечащий Врач
Background. Viruses of the Herpesviridae family are DNA-containing viruses prone to latent lifelong persistence in various tissues of the body after primary infection. According to WHO, 64% of people in the world under the age of 50 are infected with the
D. S. Sukhanov   +4 more
doaj   +1 more source

The role of Herpesviridae infection in the progression of comorbid somatic pathology

open access: yesAktualʹnaâ Infektologiâ, 2021
Background. The objective was to study the peculiarities of cellular and humoral immunity in patients with chronic obstructive pulmonary disease (COPD) group B and C, GOLD 2–3, who have signs of metabolic syndrome (MS) and Herpesviridae infection. Materials and methods.
Bychkova, S.A.   +2 more
openaire   +2 more sources

Geographic and Molecular Insights Into Bat Diversity and Virus Distribution in China: Implications for Public Health

open access: yesJournal of Medical Virology, Volume 98, Issue 1, January 2026.
ABSTRACT Bats are key reservoirs of zoonotic viruses, yet comprehensive data on their diversity and viral carriage across China remain limited. This study compiled national‐level data on bat taxonomy, distribution, and associated viruses by integrating information from peer‐reviewed publications (PubMed), the ZOVER database, and cytochrome oxidase I ...
Yameng Xu   +16 more
wiley   +1 more source

Strategic Preparedness of Broad‐Spectrum Antivirals for Rapid Response Towards Next Pandemics

open access: yesSmall Science, Volume 6, Issue 1, January 2026.
Nanoengineered broad‐spectrum antivirals (BSAs) represent a transformative approach to pandemic preparedness. Unlike virus‐specific drugs requiring separate development, BSAs act across multiple viral families through nanoengineering strategies that enhance solubility, bioavailability, and host‐targeted activity.
Sanoj Rejinold N   +2 more
wiley   +1 more source

Exploring the Antiviral Potential of Tungsten Oxide Nanoparticles Against Herpes Simplex Virus Type 1: A Promising Alternative to Acyclovir

open access: yesIET Nanobiotechnology, Volume 2026, Issue 1, 2026.
Herpes simplex virus type 1 (HSV‐1) is responsible for the majority of cold sores, herpetic keratitis‐induced blindness, profound skin lesions, and encephalitis that can be fatal. Currently, acyclovir and its derivatives are the first‐line therapy for the treatment of HSV‐1 infection.
Abdulhussain Kadhim Jwaziri   +7 more
wiley   +1 more source

Opportunistic infections in pediatrics: when to suspect and how to approach

open access: yesJornal de Pediatria (Versão em Português), 2020
Objectives: To describe the characteristics of opportunistic infections in pediatrics regarding their clinical aspects, as well as the diagnostic strategy and treatment.
Maria Isabel de Moraes-Pinto   +1 more
doaj   +1 more source

Refractory pemphigus foliaceus associated with herpesvirus infection: case report

open access: yesRevista do Instituto de Medicina Tropical de São Paulo
Pemphigus foliaceus (PF) is an autoimmune disease characterized by blistering of the skin. Infections caused by members of the herpesviridae family have been suggested as a possible triggering factor for pemphigus vulgaris (PV), but not for PF.
Nurimar C. Fernandes   +3 more
doaj   +1 more source

Rumex Species: Phytochemistry, Pharmacology and Nutritional Potential for Food and Health Applications

open access: yesFood Science &Nutrition, Volume 13, Issue 12, December 2025.
Rumex dentatus, R. vesicarius, and Emex spinosa are traditionally used for managing gastrointestinal, respiratory, hepatic, and inflammatory disorders. In addition to their ethnomedicinal value, some species are consumed as wild edibles. Pharmacological studies support their antimicrobial, antioxidant, hepatoprotective, cytotoxic, and antidiabetic ...
Mai Mohamed Gohar   +10 more
wiley   +1 more source

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