Results 61 to 70 of about 17,666 (176)

The Human Respiratory Virome in Health and Disease: Interactions, Dysbiosis, and Methodological Challenges

open access: yesAdvanced Genetics, Volume 6, Issue 4, December 2025.
This article examines how the respiratory virome contributes to health and disease, highlighting its interactions with the host and bacteriome. Key disease associations and present knowledge gaps are outlined. The review discusses challenges in sample collection and preprocessing, and presents future research directions for understanding virome ...
Xiaoxuan Yao, Xiaohui Zou, Bin Cao
wiley   +1 more source

Reduced anti-viral IgG repertoire in HIV-exposed but uninfected infants compared to HIV-unexposed infants

open access: yesiScience
Summary: Infants who are HIV exposed but uninfected (iHEU) have higher risk of viral infections compared to infants who are HIV unexposed (iHUU). We explored the effect of intrauterine HIV exposure on the infant antibody repertoire by quantifying plasma ...
Rachael Gachogo   +5 more
doaj   +1 more source

MicroRNAs in large herpesvirus DNA genomes: recent advances

open access: yesBiomolecular Concepts, 2016
MicroRNAs (miRNAs) are small non-coding RNAs (ncRNAs) that regulate gene expression. They alter mRNA translation through base-pair complementarity, leading to regulation of genes during both physiological and pathological processes.
Sorel Océane, Dewals Benjamin G.
doaj   +1 more source

Hemophagocytic syndrome in patients with acute myeloid leukemia undergoing intensive chemotherapy

open access: yesHaematologica, 2014
Hemophagocytic lymphohistiocytosis is a condition of immune dysregulation characterized by severe organ damage induced by a hyperinflammatory response and uncontrolled T-cell and macrophage activation.
Karen Delavigne   +12 more
doaj   +1 more source

Functional Characterization of an IL2RG Variant, a Case Report of X‐Linked T‐ B + NK + SCID

open access: yesImmunity, Inflammation and Disease, Volume 13, Issue 12, December 2025.
ABSTRACT Objectives Pathogenic variants in IL2RG, encoding the common γ chain (γc/CD132), usually lead to T − B + NK‐ X‐SCID but can, occasionally, generate a T − B + NK+ phenotype. We wanted to delineate potential mechanisms for this discrepancy.
Kristian Assing   +11 more
wiley   +1 more source

Alcohol‐Related Liver Disease and Metabolic Dysfunction‐Associated Steatotic Liver Disease: Molecular Pathogenesis and Therapeutic Interventions

open access: yesMedComm, Volume 6, Issue 12, December 2025.
Alcohol‐related (ALD) and metabolic dysfunction‐associated (MASLD) steatotic liver disease, while initiated by distinct etiologies (ethanol vs. metabolic stress), converge on shared core pathogenic pathways that drive progression. These include dysregulated lipid metabolism, programmed cell death, cellular senescence, gut dysbiosis, and immune ...
Yupin Tan   +3 more
wiley   +1 more source

Histopathological and genetic characterisation of Marek's disease in Sebright chickens from Brazil

open access: yesVeterinary Record Case Reports, Volume 13, Issue 4, December 2025.
Abstract Marek's disease is a lymphoproliferative condition caused by Gallid alphaherpesvirus 2 (Marek's disease virus), affecting primarily birds of the order Galliformes. This study reports a case of Marek's disease in Sebright chickens in Rio de Janeiro, Brazil.
Thomas Salles Dias   +5 more
wiley   +1 more source

Herpes simplex eyelid infection

open access: yesPAMJ Clinical Medicine, 2020
We report a case of a 16-year-old-child, with no pathological history, who presented to the ophthalmic emergencies for the appearance of skin lesions on his right lower eyelid, with burning sensation, evolving in the last 3 days.
Narjisse Taouri, Ouafae Cherkaoui
doaj   +1 more source

Infectious Laryngotracheitis Virus and Avian Metapneumovirus: A Comprehensive Review

open access: yesPathogens
Respiratory avian viral diseases significantly impact the world poultry sector, leading to notable economic losses. The highly contagious DNA virus, infectious laryngotracheitis virus, and the RNA virus, avian metapneumovirus, are well known for their ...
Jongsuk Mo, Jongseo Mo
doaj   +1 more source

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