Results 71 to 80 of about 175,340 (183)
Clinical‐Stage Nanatinostat Triggers Productive Epstein‐Barr Virus Lytic Replication
ABSTRACT A phase 1b/2 study of the all‐oral “kick‐and‐kill” combo nanatinostat + valganciclovir (nana‐val) showed a ~40% overall response rate in patients with relapsed/refractory Epstein‐Barr virus (EBV)‐associated lymphomas. Despite the promising results in these difficult‐to‐treat cancers, there is little known about the effects of nanatinostat on ...
Ibukun A. Akinyemi +6 more
wiley +1 more source
Prevalence of Bovine Herpesvirus-1 in cattle and buffaloes in Punjab
Aim: The aim of the present study was to identify the prevalence of Bovine Herpesvirus-1 (BHV-1) in cattle and buffaloes in the Punjab using PCR as diagnostic tool.
Gurpreet Kaur +3 more
doaj +1 more source
Importance of Viral Disease in Dairy Cow Fertility
Many viral diseases are endemic in cattle populations worldwide. The ability of many viruses to cross the placenta and cause abortions and fetal malformations is well understood.
D. Claire Wathes +3 more
doaj +1 more source
Bovine bacterial abortion caused by Escherichia coli infection
Abstract A 3‐year‐old, 500 kg Holstein cow aborted at 7 months of gestation. On histological evaluation of the fetal lungs, abundant neutrophils infiltrated the alveolar spaces, bronchi and bronchioles with intralesional Gram‐negative bacteria, immunolabelled with Escherichia coli immunohistochemistry.
Jéssica Nathyelli da Silva +4 more
wiley +1 more source
ABSTRACT Proteolysis‐targeting chimeras (PROTACs) are heterobifunctional molecules that hijack the ubiquitin‐proteasome system to drive catalytic, sub‐stoichiometric degradation of disease‐associated proteins, offering a mechanistic advantage over occupancy‐driven inhibitors and access to ‘undruggable’ targets.
Sruti Bagchi Ghosh +9 more
wiley +1 more source
Camels (Camelus dromedarius) are bred in Western Turkey, particularly in the province of Aydin, for touristic, social and cultural purposes. Bovine enterovirus‑1 (BEV‑1), Bovine herpesvirus type‑1 (BHV‑1), Bovine viral diarrhea virus (BVDV), and ...
Nural EROL +3 more
doaj +1 more source
Background: Infectious Bovine Rhinotracheitis (IBR), Infectious Pustular Balanoposthitis (IPB), Infectious Pustular Vulvovaginitis (IPV), late-term abortions, and neurological and systemic disease are common manifestations of Bovine Herpesvirus-1 (BoHV-1)
Bhaskar Ganguly +6 more
doaj +1 more source
Expression of Bovine Interleukin-1β in a Bovine Herpesvirus-1 Vector:In VitroAnalysis
In order to evaluate whether bovine herpesvirus-1 (BHV-1) could be used as a live viral vector for the expression of cytokines, we constructed a recombinant BHV-1 expressing bovine interleukin-1 beta (boIL-1 beta). The boIL-1 beta coding sequence, corresponding to the cleaved mature product, was fused with the BHV-1 glycoprotein C (gC) signal peptide ...
Raggo, Camilo +3 more
openaire +2 more sources
Objective: The present study was conducted to estimate the seroprevalence and associated risk factors of bovine herpesvirus 1 (BoHV-1) in a dairy herd in the northeast of Algiers, Algeria.
Abdenour Kaddour +5 more
doaj +1 more source
ETIOLOGICAL AND MOLECULAR BIOLOGICAL INVESTIGATION OF CAPRINE HERPESVIRUS 1 ISOLATED IN BULGARIA
From goat and bucks with genital disorders and abortions the attempts for isolation of caprine herpesvirus 1 (CHV 1) were carried out. For virus exaltation Dexametazone was used.
Raiko Peshev +3 more
doaj +1 more source

