Results 1 to 10 of about 55,053 (308)

Flavonoids Target Human Herpesviruses That Infect the Nervous System: Mechanisms of Action and Therapeutic Insights

Viruses, 2022
Human herpesviruses (HHVs) are large DNA viruses with highly infectious characteristics. HHVs can induce lytic and latent infections in their host, and most of these viruses are neurotropic, with the capacity to generate severe and chronic neurological ...
Miroslava Šudomová, Kateřina Berchová-Bímová, Alena Mazurakova, Dunja Šamec, Peter Kubatka, Sherif T. S. Hassan   +5 more
doaj   +2 more sources

Animal models of human herpesvirus infection [PDF]

Animal Models and Experimental Medicine
Human herpesvirus, a specific group within the herpesvirus family, is responsible for a variety of human diseases. These viruses can infect humans and other vertebrates, primarily targeting the skin, mucous membranes, and neural tissues, thereby ...
Ziqing Jia, Dong Zhang, Lin Zhu, Jing Xue   +3 more
doaj   +2 more sources

Interferon-Induced Transmembrane Proteins Inhibit Infection by the Kaposi’s Sarcoma-Associated Herpesvirus and the Related Rhesus Monkey Rhadinovirus in a Cell-Specific Manner

mBio, 2021
The interferon-induced transmembrane proteins (IFITMs) are broad-spectrum antiviral proteins that inhibit the entry of enveloped viruses. We analyzed the effect of IFITMs on the gamma-2 herpesviruses Kaposi’s sarcoma-associated herpesvirus (KSHV) and the
Bojan F. Hörnich, Anna K. Großkopf, Candice J. Dcosta, Sarah Schlagowski, Alexander S. Hahn   +4 more
doaj   +1 more source

Complete genome sequence and taxonomic position of anguillid herpesvirus 1 [PDF]

, 2010
Eel herpesvirus or anguillid herpesvirus 1 (AngHV1) frequently causes disease in freshwater eels. The complete genome sequence of AngHV1 and its taxonomic position within the family Alloherpesviridae were determined. Shotgun sequencing revealed a 249 kbp
Abma-Henkens, M.H.C., Beurden, S.J., van, Bossers, A., Engelsma, M.Y., Haenen, O.L.M., Peeters, B.P.H., Peters, S.A., Rottier, P.J.M., Voorbergen-Laarman, H.A.   +8 more
core   +15 more sources

Comparison of a Genotype 1 and a Genotype 2 Macaque Foamy Virus env Gene Indicates Distinct Infectivity and Cell-Cell Fusion but Similar Tropism and Restriction of Cell Entry by Interferon-Induced Transmembrane Proteins

Viruses, 2023
Foamy viruses (FVs) are naturally found in many different animals and also in primates with the notable exception of humans, but zoonotic infections are common. In several species, two different envelope (env) gene sequence clades or genotypes exist.
Thomas Fricke, Sarah Schlagowski, Shanchuan Liu, Xiaoliang Yang, Uwe Fiebig, Artur Kaul, Armin Ensser, Alexander S. Hahn   +7 more
doaj   +1 more source

Antibodies Targeting KSHV gH/gL Reveal Distinct Neutralization Mechanisms

Viruses, 2022
Kaposi’s sarcoma herpesvirus (KSHV) is associated with a significant disease burden, in particular in Sub-Sahara Africa. A KSHV vaccine would be highly desirable, but the mechanisms underlying neutralizing antibody responses against KSHV remain largely ...
Thomas Fricke, Anna K. Großkopf, Armin Ensser, Marija Backovic, Alexander S. Hahn   +4 more
doaj   +1 more source

Genetic and Functional Characterization of Congenital HCMV Clinical Strains in Ex Vivo First Trimester Placental Model

Pathogens, 2023
Human cytomegalovirus (HCMV) is the leading cause of congenital viral infection, leading to a variety of symptoms in the unborn child that range from asymptomatic to death in utero.
Deborah Andouard, Valentin Tilloy, Elodie Ribot, Melissa Mayeras, Daniel Diaz-Gonzalez, Chahrazed El Hamel, Fabienne Piras-Douce, Nathalie Mantel, Sophie Alain   +8 more
doaj   +1 more source

Anti-CMV therapy, what next? A systematic review

Frontiers in Microbiology, 2023
Human cytomegalovirus (HCMV) is one of the main causes of serious complications in immunocompromised patients and after congenital infection. There are currently drugs available to treat HCMV infection, targeting viral polymerase, whose use is ...
Claire Gourin, Sophie Alain, Sophie Alain, Sébastien Hantz, Sébastien Hantz   +4 more
doaj   +1 more source

Investigation on colorectal cancer and human herpesvirus infection among Algerian patients

Journal of Infection in Developing Countries, 2023
Introduction: Herpesviruses are a widespread family of double-stranded DNA viruses that establish life-long persistent infection in their hosts. Cumulative evidence tends to argue for the association of human herpesviruses, such as Kaposi's sarcoma ...
Amina Bouchemal, Joan Martí Carreras, Lydia Khireddine, Ahmed Amir Bouchemal, Fares Nasri, Piet Maes, Abderrezak Ghidouche, Fatiha Bedjou   +7 more
doaj   +1 more source

The impact of viral infections on the results of hemopoietic stem cell transplantation in patients with hematologic malignancies

Журнал инфектологии, 2021
Study Objective: to assess the impact of herpesviruses infections reactivation and concomitant chronic hepatitis C infection (CHC) on complications and one-year survival after hemopoietic stem cell transplantation (HSCT) in patients with hematologic ...
T. V. Antonova, O. E. Pobegalova, M. S. Nozhkin, M. A. Romanova, O. V. Gorchakova   +4 more
doaj   +1 more source