Results 11 to 20 of about 47,471 (249)
Structural Insights Into the Nuclear Import of Gallid Alphaherpesvirus 1 Large Tegument Protein. [PDF]
MicrobiologyopenThe study identifies and characterizes a bipartite nuclear localization signal within the GaAHV‐1 UL36 large tegument protein, revealing its structural interaction with importin α/β1 and confirming a conserved mechanism of nuclear import through biochemical, crystallographic, and mutational analyses.
Nath BK +7 more
europepmc +2 more sources
Viruses, 2022 Human herpesviruses (HHVs) are large DNA viruses with highly infectious characteristics. HHVs can induce lytic and latent infections in their host, and most of these viruses are neurotropic, with the capacity to generate severe and chronic neurological ...
Miroslava Šudomová +5 more
doaj +1 more source
APOBECs and Herpesviruses [PDF]
Viruses, 2021 The apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like (APOBEC) family of DNA cytosine deaminases provides a broad and overlapping defense against viral infections. Successful viral pathogens, by definition, have evolved strategies to escape restriction by the APOBEC enzymes of their hosts. HIV-1 and related retroviruses are thought to be
Adam Z. Cheng +8 more
openaire +3 more sources
Detection of Herpesviruses in Wild Bird Casualties in Slovenia
Frontiers in Veterinary Science, 2022 The complete host range of avian herpesviruses in wild birds is unknown, and information about nucleotide sequences is available only in limited cases.
Zoran Žlabravec +7 more
doaj +1 more source
Cross-Species Insights Into Gamma Herpesvirus Transcriptomes: Long-Read and Multi-Omics Perspectives. [PDF]
J Med VirolABSTRACT Comparative transcriptome analyses of gamma herpesviruses have been revolutionized by long‐read sequencing and integrative multi‐omics approaches, enabling unprecedented resolution of viral gene expression. Cross‐species studies of Kaposi's sarcoma‐associated herpesvirus (KSHV), Epstein–Barr virus (EBV), and murine gamma herpesvirus 68 (MHV68)
Shekhar R +4 more
europepmc +2 more sources
Potential Application of the CRISPR/Cas9 System against Herpesvirus Infections. [PDF]
, 2018 The CRISPR/Cas9 system has been applied in the genome editing and disruption of latent infections for herpesviruses such as the herpes simplex virus, Epstein⁻Barr virus, cytomegalovirus, and Kaposi's sarcoma-associated herpesvirus.
Chen, Yuan-Chuan +3 more
core +2 more sources
Herpesvirus late gene expression: a viral-specific Pre-Initiation Complex is key
Frontiers in Microbiology, 2016 During their productive cycle, herpesviruses exhibit a strictly regulated temporal cascade of gene expression that can be divided into three general stages: immediate-early (IE), early (E) and late (L).
Henri eGruffat +14 more
doaj +1 more source
Experimental Justification of Reprofiling of the Drug Maxar® for the Treatment of Viral Infections
Антибиотики и Химиотерапия, 2023 Relevance. The development of highly effective broad-spectrum antiviral agents is one of the priorities in medicine, virology, and pharmacology. The strategy of repurposing (repositioning) registered drugs is of special interest along with significant ...
T. S. Zaporozhets +7 more
doaj +1 more source
Prolonged Herpetic Keratitis in Chronic Sinusitis and Tonsillitis: Experience of Practical Solutions
Oftalʹmologiâ, 2023 Aim: to describe the experience of practical solutions for herpetic keratitis of a protracted course with latent chronic sinusitis and tonsillitis.Material and methods.
G. M. Chernakova +3 more
doaj +1 more source
Herpesviruses and Oncogenesis [PDF]
Proceedings of the National Academy of Sciences, 1972 Herpesviruses have been implicated in oncogenesis. They have been found to be etiologic agents in certain chicken, primate, and frog neoplasms. There is suggestive evidence that herpesviruses may contribute to the genesis of certain human lymphomas.
openaire +2 more sources