Results 51 to 60 of about 55,053 (308)
Herpesviral nuclear egress is a fine-tuned regulatory process that defines the nucleocytoplasmic release of viral capsids. Nuclear capsids are unable to traverse via nuclear pores due to the fact of their large size; therefore, herpesviruses evolved to ...
Sigrun Häge, Manfred Marschall
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EHV-1 Pathogenesis: Current in vitro Models and Future Perspectives [PDF]
Primary infection and pathogenesis of equine herpesvirus type 1 (EHV-1) require an intricate interaction of virus with the mucosal epithelium, mononuclear cells and the vascular endothelium.
Azab, Walid+3 more
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Revisiting the genomes of herpesviruses
Combining integrative genomics and systems biology approaches has revealed new and conserved features in the genome of human herpesvirus 6.
Bhupesh K Prusty, Adam W Whisnant
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Structural Proteomics of Herpesviruses [PDF]
Herpesviruses are highly prevalent viruses associated with numerous pathologies both in animal and human populations. Until now, most of the strategies used to prevent or to cure these infections have been unsuccessful because these viruses have developed numerous immune evasion mechanisms.
Ruddy Wattiez+3 more
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SAMHD1 … and Viral Ways around It
The SAM and HD domain-containing protein 1 (SAMHD1) is a dNTP triphosphohydrolase that plays a crucial role for a variety of different cellular functions.
Janina Deutschmann, Thomas Gramberg
doaj +1 more source
Fresh Insights into Disease Etiology and the Role of Microbial Pathogens. [PDF]
Pathogens have been implicated in the initiation and/or promotion of systemic sclerosis (scleroderma, SSc); however, no evidence was found to substantiate the direct contribution to this disease in past years.
FARINA, Antonella, Farina, G.a.2.
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Immunodeficiencies that predispose to pathologies by human oncogenic γ-herpesviruses
Human γ-herpesviruses include the closely related tumor viruses Epstein Barr virus (EBV) and Kaposi sarcoma-associated herpesvirus (KSHV). EBV is the most growth-transforming pathogen known and is linked to at least seven human malignancies. KSHV is also
B. Damania, C. Münz
semanticscholar +1 more source
Controversial role of herpesviruses in Alzheimer’s disease
The controversial hypothesis that microbes might trigger Alzheimer’s disease (AD) has been debated for decades. Around 30 years ago, researchers in the United Kingdom discovered DNA of human herpes simplex virus 1 (HSV1) in postmortem brain samples of AD
R. Rizzo
semanticscholar +1 more source
Evolution of the G+C content frontier in the rat cytomegalovirus genome [PDF]
Within the 230138 bp of the rat cytomegalovirus (RCMV) genome, the G+C content changes abruptly at position 142644, constituting a G+C content frontier. To the left of this point, overall G+C content is 69.2%, and to the right it is only 47.6%.
Gatherer, Derek
core +3 more sources
An alphaherpesvirus exploits antimicrobial beta-defensins to initiate respiratory tract infection [PDF]
beta-Defensins protect the respiratory tract against the myriad of microbial pathogens entering the airways with each breath. However, this potentially hostile environment is known to serve as a portal of entry for herpesviruses.
Boyen, Filip+8 more
core +2 more sources