Results 51 to 60 of about 55,053 (308)

‘Come together’—The Regulatory Interaction of Herpesviral Nuclear Egress Proteins Comprises Both Essential and Accessory Functions

open access: yesCells, 2022
Herpesviral nuclear egress is a fine-tuned regulatory process that defines the nucleocytoplasmic release of viral capsids. Nuclear capsids are unable to traverse via nuclear pores due to the fact of their large size; therefore, herpesviruses evolved to ...
Sigrun Häge, Manfred Marschall
doaj   +1 more source

EHV-1 Pathogenesis: Current in vitro Models and Future Perspectives [PDF]

open access: yes, 2019
Primary infection and pathogenesis of equine herpesvirus type 1 (EHV-1) require an intricate interaction of virus with the mucosal epithelium, mononuclear cells and the vascular endothelium.
Azab, Walid   +3 more
core   +1 more source

Revisiting the genomes of herpesviruses

open access: yeseLife, 2020
Combining integrative genomics and systems biology approaches has revealed new and conserved features in the genome of human herpesvirus 6.
Bhupesh K Prusty, Adam W Whisnant
openaire   +4 more sources

Structural Proteomics of Herpesviruses [PDF]

open access: yesViruses, 2016
Herpesviruses are highly prevalent viruses associated with numerous pathologies both in animal and human populations. Until now, most of the strategies used to prevent or to cure these infections have been unsuccessful because these viruses have developed numerous immune evasion mechanisms.
Ruddy Wattiez   +3 more
openaire   +4 more sources

SAMHD1 … and Viral Ways around It

open access: yesViruses, 2021
The SAM and HD domain-containing protein 1 (SAMHD1) is a dNTP triphosphohydrolase that plays a crucial role for a variety of different cellular functions.
Janina Deutschmann, Thomas Gramberg
doaj   +1 more source

Fresh Insights into Disease Etiology and the Role of Microbial Pathogens. [PDF]

open access: yes, 2016
Pathogens have been implicated in the initiation and/or promotion of systemic sclerosis (scleroderma, SSc); however, no evidence was found to substantiate the direct contribution to this disease in past years.
FARINA, Antonella, Farina, G.a.2.
core   +1 more source

Immunodeficiencies that predispose to pathologies by human oncogenic γ-herpesviruses

open access: yesFEMS Microbiology Reviews, 2019
Human γ-herpesviruses include the closely related tumor viruses Epstein Barr virus (EBV) and Kaposi sarcoma-associated herpesvirus (KSHV). EBV is the most growth-transforming pathogen known and is linked to at least seven human malignancies. KSHV is also
B. Damania, C. Münz
semanticscholar   +1 more source

Controversial role of herpesviruses in Alzheimer’s disease

open access: yesPLoS Pathogens, 2020
The controversial hypothesis that microbes might trigger Alzheimer’s disease (AD) has been debated for decades. Around 30 years ago, researchers in the United Kingdom discovered DNA of human herpes simplex virus 1 (HSV1) in postmortem brain samples of AD
R. Rizzo
semanticscholar   +1 more source

Evolution of the G+C content frontier in the rat cytomegalovirus genome [PDF]

open access: yes, 2008
Within the 230138 bp of the rat cytomegalovirus (RCMV) genome, the G+C content changes abruptly at position 142644, constituting a G+C content frontier. To the left of this point, overall G+C content is 69.2%, and to the right it is only 47.6%.
Gatherer, Derek
core   +3 more sources

An alphaherpesvirus exploits antimicrobial beta-defensins to initiate respiratory tract infection [PDF]

open access: yes, 2020
beta-Defensins protect the respiratory tract against the myriad of microbial pathogens entering the airways with each breath. However, this potentially hostile environment is known to serve as a portal of entry for herpesviruses.
Boyen, Filip   +8 more
core   +2 more sources

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