Results 151 to 160 of about 81,802 (259)

Hydroxamic Acids as HDAC Inhibitor Drug Leads for Malaria

Medicinal Research Reviews, Volume 46, Issue 6, Page 1477-1498, November 2026.
ABSTRACT Malaria is a global health threat, with an estimated 282 million cases and 610,000 malaria‐associated deaths reported in 2024. Most mortality is due to infection by Plasmodium falciparum parasites, with the highest burden occurring in Sub‐Saharan Africa.
Wisam A. Dawood, Jacinta R. Macdonald, Christian Anzenhofer, Tina S. Skinner‐Adams, Robert C. Reid, Thomas Kurz, David P. Fairlie, Katherine T. Andrews   +7 more
wiley   +1 more source

Cross-species incompatibilities offer new insights into the functional consequences of satellite DNA evolution. [PDF]

Chromosome Res
Ridgway AM, Lamelza P, Lampson MA, Levine MT.   +3 more
europepmc   +1 more source

Epigenetics of heterochromatin

Journal of Biosciences, 2004
openaire   +2 more sources

Integrated Reproductive and Cytogenetic Assessment of Infertility in a Captive Jaguar (Panthera onca)

Veterinary Medicine and Science, Volume 12, Issue 6, November 2026.
Integrated reproductive and cytogenetic assessment of infertility in a captive jaguar pair identified normal chromosomal status in both individuals, whereas impaired semen quality in the male likely represents a major limiting factor for reproductive success under the observed conditions.
Marie Altmanová, Julie Strand, Kathrine Thejll Kirchhoff, Zuzana Majtánová   +3 more
wiley   +1 more source

Senescent Mesenchymal Stromal Cells Drive Stem Cell Aging Through Dysregulated Chemokine Synthesis

Aging Cell, Volume 25, Issue 11, November 2026.
Senescent MSCs do more than fuel inflammaging: they disrupt the chemokine signals that maintain stem cell function. We propose that restoring this signaling balance through senolytics, senomorphics, or MSC rejuvenation may preserve regenerative capacity during aging. ABSTRACT Aging is accompanied by a progressive decline in tissue regenerative capacity,
Shaianne N. Stein, Lorena R. Braid
wiley   +1 more source

LncRNA Gas5 directs SUV39H2 to establish heterochromatin and maintain genome stability. [PDF]

Protein Cell
Liu J, Yang J, Ye W, Zhang D, Su N, Wang H, Zhang Y, Gao S, Kang L.   +8 more
europepmc   +1 more source

Histone Modifications at the Intersection of Aging, Neuroinflammation and Metabolism in Alzheimer's Disease

Aging Cell, Volume 25, Issue 11, November 2026.
This review examines how histone modifications integrate aging, metabolic dysfunction and neuroinflammation to shape persistent, cell‐type‐specific chromatin states in Alzheimer's disease. By distinguishing causal regulation from association through perturbation, persistence and reversibility, it highlights metabolic–epigenetic feedback loops and ...
Junyi Liang, Huawen Cao, Xiumin Ren, Nan Sha, Xueqing Han, Ling Jiang, Bin Liu, Weiming Zhao   +7 more
wiley   +1 more source

DDM1 safeguards the stability of a Complex plant genome. [PDF]

Plant Cell
Pereyra-Bistraín LI.
europepmc   +1 more source

Heterochromatin [PDF]

, 2018
openaire   +1 more source

Whole‐genome duplication promotes phenotypic and genetic adaptation to elevation

New Phytologist, Volume 252, Issue 4, Page 1620-1631, November 2026.
Fitness of diploids (2x) and tetraploids (4x) of Biscutella laevigata from low (circles) and high (triangles) elevation transplanted across elevation at 585, 1236 and 1967 m above sea level. Summary Whole‐genome duplication (WGD) is often considered as either an adaptive dead‐end or a facilitator of rapid adaptation under changing environments.
Sandra Grünig, Marc Beringer, Christian Parisod   +2 more
wiley   +1 more source