Results 171 to 180 of about 75,723 (273)

Characterization of Harderian Gland‐Derived Plasma Cells in Chicken

European Journal of Immunology, Volume 56, Issue 6, June 2026.
An isolation protocol for plasma cells (PC) from the chicken Harderian gland (HG) was established, and analyses of PCs revealed a FSChigh/CD45med/sIgpos/CD57pos/CXCR4high/TACIlow phenotype. Presence of CXCL12 and BAFF around HG PCs suggests a contribution of CXCL12–CXCR4 and BAFF–TACI to PC localization and survival.
D. von La Roche, I. Naumann, E. Szőcs, V. Halasy, M. Kohn, B. Kaspers, N. Nagy, S. Härtle   +7 more
wiley   +1 more source

Heterochromatin [PDF]

, 2020
openaire   +1 more source

Epigenetic control of telomeric RNA maintains heterochromatin in telomerase-driven cancers. [PDF]

Signal Transduct Target Ther
Price JDW, Vizeacoumar FS, Abuhussein O, Maranda V, Zhang Y, Adachi H, Nguyen K, Kyrylenko L, Rangel-Pozzo A, Dong H, Gong L, Materi A, Walke P, Ganapathysamy A, Denomy C, Freywald T, Dahiya R, Elhasasna H, Saxena A, Vizeacoumar JP, Patel H, Rajamanickam K, de Oliveira DM, Lazell-Wright M, Morales AM, Aggarwal A, Xu JL, Alli N, Munhoz EP, Gao P, Salsman J, Dahiya DK, Kola NS, Gonzalez-Lopez C, Thibault P, Levin M, Dellaire G, Jette N, Groot G, Köbel M, Lee CH, Hopkins L, Krishnan A, Ahmed S, Eskiw C, Barakat KH, Thakur A, Wu Y, DePinho RA, Mai S, Yu YT, Wong JMY, Freywald A, Vizeacoumar FJ.   +53 more
europepmc   +1 more source

Lamin B1 safeguards the B cell genome and shapes lymphoma outcome

HemaSphere, Volume 10, Issue 6, June 2026.
Abstract Lamin B1 is a structural component of the nuclear lamina that participates in genome organization and transcriptional control. During adaptive immune responses, B lymphocytes in germinal centers (GCs) undergo clonal expansion and programmed DNA damage at immunoglobulin loci, while simultaneously downregulating Lamin B1.
Filip Filipsky, Katarina B. Chapman, Johannes Bloehdorn, Oscar Maiques, Abigail Lee, Andrew Clear, Jun Wang, John Gribben, Michael Hausmann, Christoph Cremer, Andrejs Braun, Marta C. Sallan, Tanya Klymenko   +12 more
wiley   +1 more source

Repressive chromatin regulates fibrotic potential through Suv39h1 in the heart. [PDF]

Cardiovasc Res
Koopmans T, van Rooij E.
europepmc   +1 more source

Unveiling the epigenetic and stress-responsive function of histone H1 in plants. [PDF]

Plant Signal Behav
Bae MJ, Zareen S, Yun H, Ali A, Bader ZE, Park K, Albakri N, Jung YJ, Yun DJ, Park J.   +9 more
europepmc   +1 more source

The Effect of Protein Tagging on Aggregation and Phase Separation

Journal of Cellular Biochemistry, Volume 127, Issue 6, June 2026.
ABSTRACT Protein tags are widely used for purification, solubilization, detection, and imaging, yet they can substantially alter protein self‐assembly. This interference is particularly significant for intrinsically disordered proteins and low‐complexity domains, whose aggregation and phase separation are mediated by weak multivalent interactions that ...
Harunobu Saito, Kenji Sugase
wiley   +1 more source

In the <i>IMD2</i> gene of <i>Saccharomyces cerevisiae</i>, the expression memory suppresses the induction of expression during guanosine triphosphate depletion. [PDF]

PNAS Nexus
Yokosawa T, Ayano T, Oki M.
europepmc   +1 more source

Beyond the Known and Established Neurodegenerative Effects: Roles of APOE Across a Wide Spectrum of Pathophysiological Condition

MedComm, Volume 7, Issue 6, June 2026.
APOE is widely recognized for its role in neurodegeneration and cardiovascular disease, but its different genotypes also influence body composition, affecting obesity, bone density, and muscle mass, through their central role in lipid transport and metabolism.
Miriam Frosina, Samantha Maurotti, Alberto Castagna, Tiziana Montalcini, Arturo Pujia, Luca Tirinato   +5 more
wiley   +1 more source

Microcephaly-associated genes asp and Sas4 influence chromatin organization and nuclear lamina structure in Drosophila melanogaster. [PDF]

Development
Mengistu DY, Marzullo M, Pellacani C, Marchetti M, Terribili M, Montivero Morales E, Somma MP, Ciapponi L.   +7 more
europepmc   +1 more source