Results 161 to 170 of about 75,723 (273)

Epigenetics of heterochromatin

Journal of Biosciences, 2004
openaire   +2 more sources

Lipids Contribute to Heterochromatin Condensation Revealed by Quantitative Raman-Brillouin Microscopy. [PDF]

JACS Au
Machida M, Kajimoto S, Shibuya R, Isono M, Watabe M, Oma Y, Hibino K, Fujii K, Okumura M, Harata M, Shibata A, Nakabayashi T.   +11 more
europepmc   +1 more source

The Polymers of Life: Exploring Cellular Function Through Polymer Concepts

Advanced Science, Volume 13, Issue 33, 15 June 2026.
Biomolecular phase separation reveals that a hidden layer of cellular organization is governed by the principles of polymer science. This review bridges polymer physics and cell biology, offering a primer on fundamental concepts, proposing a framework for interrogating cellular function, and synthesizing biophysical methods for decoding macromolecular ...
Mark Chen, Ashutosh Chilkoti
wiley   +1 more source

mGem: Cut4/Apc1 and its prion form at the cross roads of cell cycle regulation, heterochromatin organization, RNAi, stress response, and evolution. [PDF]

mBio
Sharma S, Singh J.
europepmc   +1 more source

Toward a detailed molecular characterization of the crystal region on the Y chromosome

, 2019
The crystal-Stellate system is one of the most studied examples of heterochromatin-euchromatin interaction in Drosophila melanogaster. The loss of the heterochromatic h11 region on the Y chromosome, called “crystal” region (or Suppressor of Stellate ...
D’Attis Simona, Fanti Laura, Pimpinelli Sergio, Massari Serafina, Bozzetti Maria, Specchia Valeria, Marchetti Marcella, Berloco Maria   +7 more
core  

T‐Cell Exhaustion in the Tumor Microenvironment: Subcellular Dysfunction, Pan‐Cancer Characteristics, and Therapeutic Interventions

Advanced Science, Volume 13, Issue 33, 15 June 2026.
This study elucidates the mechanisms of subcellular multidimensional collapse in exhausted T cells. By specifically targeting the nucleus, mitochondria, and endoplasmic reticulum, strategic interventions can effectively remodel the compromised organelle network. This integrated approach drives comprehensive T cell resuscitation, ultimately establishing
Mingxing Wang, Wanhui Dong, Jian Chen, Zhangjie Zhou, Shujuan Fu, Tingting Wu, Haiyan Jiang, Zhiying Wang, Zhixian Zhong, Yi Zhong   +9 more
wiley   +1 more source

Overview of Cytogenetics in the Subtribe Orchidinae (Orchidaceae) in the Mediterranean Region. [PDF]

Plants (Basel)
Turco A, Wagensommer RP, Albano A, Medagli P, Perrino EV, D'Emerico S.   +5 more
europepmc   +1 more source

Neurocognitive Aging Following Acute Illness: Pathobiology and a Framework for Developing Neurotherapeutic Agents

Brain and Behavior, Volume 16, Issue 6, June 2026.
In this review, we discuss the scientific basis for how neurocognitive aging occurs after critical illness, including sepsis, trauma, and burns, and the clinical need to develop therapies to reduce inflammation, protect the blood–brain barrier, remove senescent cells, and enhance neuroplasticity.
Errin Lawrence, Daniel Fulton, Poppy Brown, Subashini Suresh, Mark Morris, Paraskevi Goggolidou, Sree Chaithanya, Marcus Abbawy, Amelia Wild, Prashant Nasa, Niharika A. Duggal, Fang Gao‐Smith, Zubair Ahmed, Suresh Renukappa, Tonny Veenith   +14 more
wiley   +1 more source

The basic domain of Suv39h2 buffers mitoxantrone-induced heterochromatin destabilization. [PDF]

iScience
Świst-Rosowska KM, Ching RW, Koschorz B, Galan C, Engist B, Jenuwein T.   +5 more
europepmc   +1 more source

Identification of Novel Small‐Molecule Inhibitors Targeting KDM5B and Evaluation of Their Antitumour Effects

Cancer Medicine, Volume 15, Issue 6, June 2026.
ABSTRACT KDM5B, a member of the KDM5 family of histone demethylases, plays a critical role in transcriptional repression by demethylating H3K4me2/3. It regulates key biological processes such as development, stem cell maintenance, and oncogenesis, and its aberrant expression is implicated in various cancers. Accordingly, KDM5B is considered a promising
Tomoaki Hara, Sikun Meng, Masamitsu Konno, Naohiro Nishida, Jun Koseki, Kanji Meguro, Yasuhiko Kawano, Toshiya Morie, Shingo Dan, Taroh Satoh, Shuji Akai, Kazutake Tsujikawa, Hidetoshi Eguchi, Masaki Mori, Yutaka Miura, Nobuhiro Nishiyama, Hideshi Ishii   +16 more
wiley   +1 more source