Results 171 to 180 of about 117,333 (292)
Constitutive Heterochromatin Distribution in the Chromosomes of Pomacentrid Fishes (Perciformes).
, 1999 Akinori Takai, Yoshio Ojima
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Aging of the Hematopoietic System: Mechanisms, Consequences, and Systemic Interactions
Aging Cell, Volume 25, Issue 2, February 2026.Hematopoietic aging arises from intrinsic stem‐cell decline and bone‐marrow niche dysfunction, leading to myeloid skewing, immunosenescence, and clonal hematopoiesis. These changes drive systemic inflammation and multi‐organ disease, which in turn further disrupt the bone‐marrow niche and hematopoietic stem cell (HSC) function, creating a vicious cycle
Masashi Miyawaki +3 more
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Comparative analysis of C-heterochromatin, ribosomal and telomeric DNA markers in chromosomes of Pamphagidae grasshoppers from Morocco [PDF]
, 2019 Olesya Buleu +3 more
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Cancer Science, Volume 117, Issue 2, Page 429-444, February 2026.The present study revealed for the first time that TGM2 could regulate the radiosensitivity of cervical cancer via POGZ‐mediated DNA DSB repair. Our findings revealed that TGM2 regulates the radiosensitivity of cervical cancer and demonstrated that POGZ serves as a bridge linking TGM2 to the DNA damage repair process, and suggested a novel mechanistic ...
Yunbo Chi +5 more
wiley +1 more source
The Plant Journal, Volume 125, Issue 3, February 2026.Significance Statement Contrary to expectation, NUPTs do not necessarily have a deleterious or ultimately neutral impact, nor are they necessarily purged from the genome. Instead, they can proliferate and eventually become fixed, generating new and novel genes, gene regions and regulatory elements, thereby significantly contributing to plant nuclear ...
Lorenzo Carretero‐Paulet +2 more
wiley +1 more source
Therapeutic targeting of chromatin alterations in leukemia and solid tumors
International Journal of Cancer, Volume 158, Issue 2, Page 382-408, 15 January 2026.Abstract Alterations in chromatin conformation and post‐translational modification of histones have become increasingly recognized as critical drivers of cancer development, progression, and therapy resistance. Recent advances in drug development have led to the establishment of several highly selective small molecule inhibitors, several of which are ...
Florian Perner +7 more
wiley +1 more source
Basis for lineage-determining pioneer factors targeting distinct repressed chromatin states. [PDF]
Sci AdvKatznelson A +3 more
europepmc +1 more source
A ‘higher order’ of telomere regulation: telomere heterochromatin and telomeric RNAs
, 2009 Stefan Schoeftner, Marı́a A. Blasco
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Epigenetic reprogramming in multiple myeloma—Challenges and opportunities
International Journal of Cancer, Volume 158, Issue 2, Page 423-432, 15 January 2026.Abstract In cancer, mutational processes act in concert with epigenetic reprogramming to endow malignant cells with hallmark properties that underpin tumorigenesis. Compared with the relatively rigid and slow processes of genetic evolution, the plastic nature of chromatin enables cells to adapt to a changing environment more rapidly.
Subhasree Kumar +2 more
wiley +1 more source