Results 211 to 220 of about 133,661 (356)

Effects of TcFLA‐1BP and TcGP72 Deletion on the Infectivity and Survival of Trypanosoma cruzi in Cell Cultures

open access: yesCell Biology International, Volume 49, Issue 11, Page 1395-1410, November 2025.
ABSTRACT Chagas disease, caused by the protozoan Trypanosoma cruzi, is a neglected tropical disease with limited treatment options and no available vaccine. Understanding the role of proteins in the parasite's biological cycle is critical for advancing vaccine development and optimizing therapies.
Normanda Souza‐Melo   +2 more
wiley   +1 more source

An extra band within the human 9qh+ region that behaves like the surrounding constitutive heterochromatin. [PDF]

open access: bronze, 1994
José Luís Fernández   +4 more
openalex   +1 more source

Targeting Histone H3K9 Methyltransferase G9a as a Potential Therapeutic Strategy for Neuropsychiatric Disorders

open access: yesMedicinal Research Reviews, Volume 45, Issue 6, Page 1547-1563, November 2025.
ABSTRACT Neuropsychiatric disorders present a multifaceted challenge, characterized by cognitive, social, and motor impairments with manifold underlying mechanisms. Recent attention has turned to epigenetic mechanisms, particularly histone lysine methyltransferases (HKMTs), such as G9a, in understanding fundamental pathogenesis.
Malak Hajar   +4 more
wiley   +1 more source

Decoding Gene Expression Changes in Cerebral Tumors: Before and After Radiotherapy

open access: yesMedicinal Research Reviews, Volume 45, Issue 6, Page 1651-1661, November 2025.
ABSTRACT Cerebral tumors, particularly in pediatric patients, pose a significant challenge in oncology. Radiotherapy is a crucial component of the multimodal treatment approach for these tumors. Understanding the molecular basis of these tumors, particularly their response to radiotherapy, is crucial for improving treatment outcomes and patient ...
Ahana Maitra   +9 more
wiley   +1 more source

Guanylate‐binding proteins: emerging critical functions in plant development, immunity and stress response

open access: yesNew Phytologist, Volume 248, Issue 3, Page 1171-1179, November 2025.
Summary Guanylate‐binding proteins (GBPs) are large GTPases that belong to the Dynamin Superfamily Protein family. In humans, GBPs are well‐characterized interferon‐induced GTPases, playing a central role in cell‐autonomous innate immunity against infections, inflammation and cancer. GBPs orthologs have been identified in plants only recently.
Lucie Fernandez‐Lochu   +2 more
wiley   +1 more source

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