Results 221 to 230 of about 102,928 (311)

Patterns of crossover distribution in Drosophila mauritiana necessitate a re-thinking of the centromere effect on crossing over. [PDF]

Genetics
Hawley RS, Price A, Li H, Jagannathan M, Staber C, Hughes SE, Williams S, Perera A, Egidy RR, Lawlor A, Miller DE, Blumenstiel JP.   +11 more
europepmc   +1 more source

Influence of heterochromatin on chiasma localization and terminalization in maize [PDF]

, 1995
Rosana Torrezan, Maria Suely Pagliarini
openalex   +1 more source

Reduction of DNA Topoisomerase Top2 Reprograms the Epigenetic Landscape and Extends Health and Life Span Across Species

Aging Cell, Volume 24, Issue 6, June 2025.
This study demonstrates that reducing the enzyme topoisomerase Top2 or its mammalian homolog TOP2B promotes longevity across multiple species, including yeast, worms, and mice. At the cellular/molecular level, TOP2B reduction mitigates the major cellular aging hallmarks such as epigenetic alterations, cell senescence, lysosomal biogenesis, and ...
Man Zhu, Meng Ma, Lunan Luo, Feiyang Li, Jiashun Zheng, Yan Pan, Lu Yang, Ying Xiao, Ziyan Wang, Bo Xian, Yi Zheng, Hao Li, Jing Yang   +12 more
wiley   +1 more source

Histone variant H2A.W7 represses meiotic crossover formation in <i>Arabidopsis</i> heterochromatin. [PDF]

Proc Natl Acad Sci U S A
Kuo P, Tock AJ, Liu X, Topp SD, Zhong Z, Henderson IR, Lambing C.   +6 more
europepmc   +1 more source

The Suppression by Protein Synthesis Inhibitors of Sister Chromatid Exchanges Induced by Exogenous Agents in the Euchromatin and Heterochromatin of Chinese Hamster Cells

, 1981
Akira Sono, Kengo Sakaguchi
openalex   +2 more sources

Karyotypes of common voles from Kyrghyzstan and heterochromatin variation in the sex chromosomes ofMicrotus kirgisorum(Rodentia, Arvicolidae) [PDF]

, 1995
Jan Zima, Miloš Macholán
openalex   +1 more source

Compressive Forces Induce Epigenetic Activation of Aged Human Dermal Fibroblasts Through ERK Signaling Pathway

Aging Cell, Volume 24, Issue 6, June 2025.
Direct activation and rejuvenation of aged fibroblasts through the application of mechanical forces in a 3D spheroid culture model. The ERK signaling pathway was revealed as a key underlying mechanism. ABSTRACT Age‐related changes in human dermal fibroblasts (HDFs) contribute to impaired wound healing and skin aging.
Hui Liu, Luezhen Yuan, Lucrezia Baldi, Trinadha Rao Sornapudi, G. V. Shivashankar   +4 more
wiley   +1 more source

Reorganization of H3K9me heterochromatin leads to neuronal impairment via the cascading destruction of the KDM3B-centered epigenomic network

iScience
Summary: Histone H3K9 methylated heterochromatin silences repetitive non-coding sequences and lineage-specific genes during development, but how tissue-specific genes escape from heterochromatin in differentiated cells is unclear.
Mi-Jin An, Ji-Young Kim, Jinho Kim, Dae-Hyun Kim, Geun-Seup Shin, Hyun-Min Lee, Ah-Ra Jo, Yuna Park, Yujeong Hwangbo, Chul-Hong Kim, Mi Jin Kim, Youn-Sang Jung, Jeongkyu Kim, Sangmyung Rhee, Sang-Beom Seo, Jung-Woong Kim   +15 more
doaj  

Increased phosphorylation of HP1, a heterochromatin-associated protein of Drosophila, is correlated with heterochromatin assembly.

, 1994
Joel C. Eissenberg, Yao Ge, T. Hartnett
openalex   +1 more source

Age‐Dependent Regulation of Hippocampal Inflammation by the Mitochondrial Translocator Protein in Mice

Aging Cell, Volume 24, Issue 6, June 2025.
The role of mitochondrial translocator protein (TSPO) in hippocampal inflammation is age‐dependent, with TSPO deletion drastically exacerbating inflammation in aged mice, while dampening it in young mice. This TSPO–aging interaction was linked to NF‐kβ and interferon regulatory transcriptional networks. TSPO deletion exacerbated age‐dependent depletion
Kei Onn Lai, Jia Hui Wong, Nevin Tham, Lauren Fairley, Roshan Ratnakar Naik, Yulan Wang, Sarah R. Langley, Anna M. Barron   +7 more
wiley   +1 more source