Results 221 to 230 of about 124,493 (360)

Small modifier, big decision: switching to SUMO mode adds weight to cancer stemness in mammary tumors

open access: yesMolecular Oncology, Volume 19, Issue 8, Page 2166-2170, August 2025.
Inhibition of protein SUMOylation has been shown to block tumorigenesis; however, the specific mechanisms by which SUMOylation controls the tumor‐initiating capacities remain elusive. Li et al. describe the role of Etv1 SUMOylation in cancer stem cells using mouse models of mammary gland tumorigenesis.
Veronika Yevdokimova, Yannick D. Benoit
wiley   +1 more source

Helios, a T cell-restricted Ikaros family member that quantitatively associates with Ikaros at centromeric heterochromatin [PDF]

open access: gold, 1998
K Hahm   +9 more
openalex   +1 more source

Attenuated Nuclear Tension Regulates Progerin‐Induced Mechanosensitive Nuclear Wrinkling and Chromatin Remodeling

open access: yesAdvanced Science, Volume 12, Issue 31, August 21, 2025.
The premature aging‐related progerin leads to defective nuclear morphology and is associated with disrupted molecular coupling between the extranuclear cytoskeleton and lamin‐associated nuclear envelope. It is discovered that progerin expression reduces nuclear tension, forms nuclear wrinkling, and enhances chromatin dynamics, thereby regulating ...
Ji‐Eun Park   +9 more
wiley   +1 more source

Fencing the genome: ubiquitin signaling restricts heterochromatin spread. [PDF]

open access: yesSignal Transduct Target Ther
Bakker C, Paulson J, Taneja N.
europepmc   +1 more source

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