Results 121 to 130 of about 1,614,552 (145)

RID is required for both repeat-induced point mutation and nucleation of a novel transitional heterochromatic state for euchromatic repeats. [PDF]

Nucleic Acids Res
He Z, Wu N, Yao R, Tan H, Sun Y, Chen J, Xue L, Chen X, Yang S, Hurst LD, Wang L, Huang J.   +11 more
europepmc   +1 more source

Unveiling the dynamic drivers: phase separation's pivotal role in stem cell biology and therapeutic potential. [PDF]

Stem Cell Res Ther
Lin P, Lin Y, Lu Y, Chen X, Zhou Z, Zhao X, Cui L.   +6 more
europepmc   +1 more source

Emerging roles for the nucleolus in development and stem cells.

Development
Leeke BJ, Staffhorst I, Percharde M.
europepmc   +1 more source

A function of Spalt proteins in heterochromatin organization and maintenance of genomic DNA integrity.

Development
Ostalé CM, Azpiazu N, Peropadre A, Martín M, Ruiz-Losada M, López-Varea A, Viales RR, Girardot C, Furlong EEM, de Celis JF.   +9 more
europepmc   +1 more source

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Function of heterochromatin protein 1 during DNA repair

Protoplasma, 2017
This review focuses on the function of heterochromatin protein HP1 in response to DNA damage. We specifically outline the regulatory mechanisms in which HP1 and its interacting partners are involved. HP1 protein subtypes (HP1α, HP1β, and HP1γ) are the main components of constitutive heterochromatin, and HP1α and HP1β in particular are responsible for ...
E. Bártová, Barbora Malyšková, D. Komůrková, S. Legartová, J. Suchánková, J. Krejčí, S. Kozubek   +6 more
semanticscholar   +4 more sources

Analysis of the heterochromatin protein 1 (HP1) interactome in Drosophila.

Journal of Proteomics, 2014
Heterochromatin protein 1 (HP1) was first described in Drosophila melanogaster as a heterochromatin associated protein required for epigenetic gene silencing. Most eukaryotes have at least three HP1 homologs that play differential roles in heterochromatin and euchromatin.
Hyun-Wook Ryu, Dong Hoon Lee, L. Florens, Selene K Swanson, M. Washburn, S. Kwon   +5 more
semanticscholar   +4 more sources

Heterochromatin protein 1 expression is reduced in human thyroid malignancy [PDF]

Laboratory Investigation, 2014
Owing to the loss of heterochromatin integrity that occurs during thyroid tumorigenesis, the expression of Heterochromatin Protein 1 isoforms HP1α and HP1β was assessed by immunohistochemistry in 189 thyroid tumors and non-neoplastic tissues. Expression of HP1β was significantly decreased in all thyroid lesions, except in follicular adenomas, when ...
M. Tretiakova, Sarah Bond, David Wheeler, A. Contreras, M. Kocherginsky, T. Kroll, T. Hale   +6 more
semanticscholar   +3 more sources

The Heterochronic Gene Oryza sativa LIKE HETEROCHROMATIN PROTEIN 1 Modulates miR156b/c/i/e Levels.

Journal of Integrative Plant Biology, 2020
The juvenile-to-adult transition in plants involves changes in vegetative growth and plant architecture; the timing of this transition has important implications for agriculture.
Yongtao Cui, Jingfei Cheng, Shuan Ruan, Peipei Qi, Wei Liu, Hong-wu Bian, Luhuan Ye, Yuping Zhang, Jiang Hu, Guojun Dong, Longbiao Guo, Yijing Zhang, Q. Qian, Xingming Hu   +13 more
semanticscholar   +1 more source

Heterochromatin protein 1 binds transgene arrays

Chromosoma, 1998
Heterochromatin protein 1 (HP1) of Drosophila and its homologs in vertebrates are key components of constitutive heterochromatin. Here we provide cytological evidence for the presence of heterochromatin within a euchromatic chromosome arm by immunolocalization of HP1 to the site of a silenced transgene repeat array.
FANTI, Laura, Douglas R. Dorer, Maria Berloco, Steven Henikoff, PIMPINELLI, Sergio   +4 more
openaire   +4 more sources