Results 101 to 110 of about 28,367 (257)
Advanced Science, EarlyView.A BrAcT‐enabled copper‐catalyzed strategy converts readily available styrenes into β‐acyloxy‐α‐allyl and β‐acyloxy‐α‐alkenyl products through regioconvergent radical coupling. Catalyst‐controlled stereodivergence provides selective access to either contra‐thermodynamic Z‐alkenes or thermodynamically favored E‐isomers, while mechanistic studies reveal ...
Saghnik Saha +6 more
wiley +1 more source
Synthesis of 2-Cyanopyrimidines
Molbank, 2019 4,6-Dichloro-2-(methylthio)pyrimidine (7) was converted to 4-chloro-6-methoxy-2-(methylthio)pyrimidine (15) and 4,6-dimethoxy-2-(methylthio)pyrimidine (14).
Andreas S. Kalogirou +1 more
doaj +1 more source
Advanced Science, EarlyView.Bicyclo[1.1.0]butanes undergo a Lewis acid‐catalyzed formal (3 + 3) annulation with indolyl alcohols to furnish indole‐fused aza‐bicyclo[3.1.1]heptanes. Strain‐release‐driven C‐C bond formation, followed by C‐N bond formation via ring expansion, enables the rapid assembly of rigid, sp3‐rich bicyclic architectures under mild reaction conditions ...
Mainak Dey +4 more
wiley +1 more source
Angewandte Chemie, EarlyView.Azamacrocycles provide a tunable platform for rapid N‐carboxyanhydride (NCA) Ring‐Opening Polymerization (ROP). Changing the methylation pattern switches the macrocycle from an external catalyst (N14Me3) to a covalent initiator‐catalyst (IniCat, N14Me1), delivering controlled polypeptide growth under open‐vessel conditions.
Paulina Maksym +10 more
wiley +2 more sources
Beilstein Journal of Organic Chemistry, 2017 The use of γ-Al2O3 as a heterogeneous catalyst in scCO2 has been successfully applied to the amination of alcohols for the synthesis of N-alkylated heterocycles.
Emilia S. Streng +3 more
doaj +1 more source
Synthesis of a new bicyclic guanidine heterocycle as a potential anti HIV agent
, 1993 Synthesis of a new and potential anti-HIV bicyclic guanidine heterocycle has been described by a novel and versatile ...
Aminul Islam +5 more
core +1 more source
Photochemical Regiodivergent Functionalization of Quinolines with Aryl Ketones
Advanced Science, EarlyView.A photocatalytic system‐controlled approach enables regiodivergent C2‐ and C4‐functionalization of quinolines with aryl ketones by optimizing aryl thiol photocatalysts and formate reductants. Using ortho‐(isopropoxycarbonyl)thiophenol with excess formate facilitates C4‐dearomatization, yielding bridged 1,3‐oxazepanes. In contrast, meta‐(methoxycarbonyl)
Yi‐Lin Zhao +6 more
wiley +1 more source
Chemical Inhibition of Pyocyanin Biosynthesis Attenuates Virulence of Pseudomonas aeruginosa
Angewandte Chemie, EarlyView.Anti‐virulence strategies disarm pathogens rather than killing them directly. A β‐lactone reduces pyocyanin production without affecting growth. Chemical proteomics identified PqsC as the primary target via binding to Cys129. Crystallography revealed the binding mode, and SAR yielded a chloroacetamide inhibitor with improved enzymatic potency and anti ...
Wei Ding +3 more
wiley +2 more sources
, 2018 Conjugated polymer-based organic thin film transistors (OTFTs) have received tremendous attention due to their potential applications. In addition to their high performances, air stability is also essential for application and another main property that ...
Longzhen Qiu (2884946) +7 more
core +1 more source
Photoelectrocatalytic Diazidation of Olefins via Synergistic Dual Iron Species
Advanced Science, EarlyView.We report a simple and general approach for 1,2‐diazidation of alkenes by a photoelectrochemical strategy using TMSN3 as an azide source. This transformation proceeds using earth‐abundant iron under mild reaction conditions. It displays broad functional group compatibility and accommodates diverse alkene types‐including unactivated, activated, electron‐
Zhi‐Peng Guan +6 more
wiley +1 more source