Results 1 to 10 of about 111 (101)

Mechanochemically‐Assisted Passerini Reactions: A Practical and Convenient Method for the Synthesis of Novel α‐Acyloxycarboxamide Derivatives [PDF]

ChemistryOpen, Volume 12, Issue 5, May 2023., 2023
The formation of novel α‐acyloxycarboxamides from a carboxylic acid/phenol, an aldehyde/ketone and substituted isocyanide was investigated under mechanochemical conditions in the absence of organic solvents or in the presence of a catalytic amount of H2SO4−SiO2 (solid‐assisted grinding, SAG) to create libraries of structurally complicated molecules for
Sodeeq Aderotimi Salami, Justin Bazibuhe Safari, Vincent J. Smith, Rui W. M. Krause   +3 more
wiley   +2 more sources

A Qualitative Comparison of the Reactivities of 3,4,4,5-Tetrachloro-4H-1,2,6-thiadiazine and 4,5-Dichloro-1,2,3-dithiazolium Chloride [PDF]

Molecules, 2015
The high yielding transformations of 3,4,4,5-tetrachloro-4H-1,2,6-thiadiazine into 3,5-dichloro-4H-1,2,6-thiadiazin-4-one (up to 85%) and 2-(3,5-dichloro-4H-1,2,6-thiadiazin-4-ylidene)malononitrile (up to 83%) have been investigated and compared to the ...
Andreas S. Kalogirou, Panayiotis A. Koutentis   +1 more
doaj   +2 more sources

Mechanochemistry: New Tools to Navigate the Uncharted Territory of “Impossible” Reactions [PDF]

ChemSusChem, Volume 15, Issue 17, September 7, 2022., 2022
Mission impossible: Mechanosynthesis is erroneously perceived as an enabling tool for only making greener well‐known solution‐based processes. Modern mechanochemistry is, above all, an effective tool to open synthetic paths not accessible by following conventional and well‐known pathways already reported in the literature for the classical chemistry in
Federico Cuccu, Lidia De Luca, Francesco Delogu, Evelina Colacino, Niclas Solin, Rita Mocci, Andrea Porcheddu   +6 more
wiley   +2 more sources

Oxidations of 4H‐1,2,6‐Thiadiazines

ChemistrySelect, Volume 7, Issue 45, December 6, 2022., 2022
The oxidation of various non‐S‐oxidized 4H‐1,2,6‐thiadiazines to sulfoxides and sulfones was investigated using the oxidants N2O4, m‐CPBA, Oxone, PIFA and PIDA. The scope and regioselectivity of the oxidation was examined, while the structures of several new products is supported by X‐ray crystallography.
Andreas S. Kalogirou, Andreas Kourtellaris, Panayiotis A. Koutentis   +2 more
wiley   +2 more sources

Scientific Opinion of Flavouring Group Evaluation 406 (FGE.406): (S)‐1‐(3‐(((4‐amino‐2,2‐dioxido‐1H‐benzo[c][1,2,6]thiadiazin‐5‐yl)oxy)methyl)piperidin‐1‐yl)‐3‐methylbutan‐1‐one [PDF]

EFSA Journal, Volume 16, Issue 2, February 2018., 2018
Abstract The Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF) of EFSA was requested to deliver a scientific opinion on the safety of the use of the substance (S)‐1‐(3‐(((4‐amino‐2,2‐dioxido‐1H‐benzo[c][1,2,6]thiadiazin‐5‐yl)oxy)methyl)piperidin‐1‐yl)‐3‐methylbutan‐1‐one [FL‐no: 16.129], as a flavouring substance.
EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF), Vittorio Silano, Claudia Bolognesi, Laurence Castle, Kevin Chipman, Jean‐Pierre Cravedi, Karl‐Heinz Engel, Paul Fowler, Roland Franz, Konrad Grob, Rainer Gürtler, Trine Husøy, Sirpa Kärenlampi, Maria Rosaria Milana, Karla Pfaff, Gilles Riviere, Jannavi Srinivasan, Maria de Fátima Tavares Poças, Christina Tlustos, Detlef Wölfle, Holger Zorn, Ulla Beckman Sundh, Romualdo Benigni, Mona‐Lise Binderup, Leon Brimer, Francesca Marcon, Daniel Marzin, Pasquale Mosesso, Gerard Mulder, Agneta Oskarsson, Camilla Svendsen, Jan Van Benthem, Maria Anastassiadou, Maria Carfì, Wim Mennes   +36 more
wiley   +2 more sources

Reactions of 4H-1,2,6-Thiadiazine Sulfides [PDF]

Molbank, 2022
3,5-Dichloro-4H-1,2,6-thiadiazin-4-one reacts with benzo[d]thiazole-2-thiol (1 equiv) and triethylamine (1 equiv) to give 3-(benzo[d]thiazol-2-ylthio)-5-chloro-4H-1,2,6-thiadiazin-4-one in 71% yield. The reactivity of this compound with methoxide is explored and compared with that of 3-chloro-5-(phenylthio)-4H-1,2,6-thiadiazin-4-one.
Andreas S. Kalogirou, Panayiotis A. Koutentis   +1 more
  +11 more sources

6,10-Dichloro-1-oxa-4,8-dithia-7,9-diazaspiro[4.5]deca-6,9-diene

Molbank, 2022
Reaction of 3,4,4,5-tetrachloro-4H-1,2,6-thiadiazine with 2-mercaptoethan-1-ol (1 equiv.) gave 6,10-dichloro-1-oxa-4,8-dithia-7,9-diazaspiro[4.5]deca-6,9-diene in 12% yield. The compound was fully characterized.
Andreas S. Kalogirou, Panayiotis A. Koutentis   +1 more
doaj   +1 more source

Chemistry of 3,5‐Dichloro‐4H‐1,2,6‐thiadiazine‐4‐thione

ChemistrySelect, Volume 8, Issue 45, December 5, 2023., 2023
3,5‐Dichloro‐4H‐1,2,6‐thiadiazine‐4‐thione was prepared by thionation of 3,5‐dichloro‐4H‐1,2,6‐thiadiazine‐4‐one. The chemistry of this thione was briefly investigated under thermal conditions and treatment with carbon nucleophiles, dienes and triphenylphosphine. The structures of several new products is supported by X‐ray crystallography.
Andreas S. Kalogirou, Andreas Kourtellaris, Panayiotis A. Koutentis   +2 more
wiley   +1 more source

Reactions of 4H-1,2,6-Thiadiazine Sulfides

Molbank, 2022
3,5-Dichloro-4H-1,2,6-thiadiazin-4-one reacts with benzo[d]thiazole-2-thiol (1 equiv) and triethylamine (1 equiv) to give 3-(benzo[d]thiazol-2-ylthio)-5-chloro-4H-1,2,6-thiadiazin-4-one in 71% yield.
Andreas S. Kalogirou, Panayiotis A. Koutentis   +1 more
doaj   +1 more source

5,5′-Bis[5-(9-decyl-9H-carbazol-3-yl)thien-2-yl]-4H,4′H-[3,3′-bi(1,2,6-thiadiazine)]-4,4′-dione

Molbank, 2018
Stille coupling of 5,5′-dichloro-4H,4′H-[3,3′-bi(1,2,6-thiadiazine)]-4,4′-dione (8) with 9-decyl-3-[5-(tributylstannyl)thien-2-yl]-9H-carbazole and Pd(Ph3P)2Cl2 in PhMe, at ca. 110 °C, for 2 h, gave 5,5′-bis[5-(9-decyl-9H-carbazol-3-yl)thien-2-yl]-4H,4′H-
Andreas S. Kalogirou, Panayiotis A. Koutentis   +1 more
doaj   +1 more source