Results 161 to 170 of about 28,367 (257)

Alkyl-to-Alkyl Palladium Migration Enables Remote C-C Bond Formation. [PDF]

J Am Chem Soc
Kuang Y, Zhou D, Tomanik M.
europepmc   +1 more source

Radical Sampling Enabled Saturated N-Heterocycle Cyclization. [PDF]

J Am Chem Soc
Cai Q, Bissonnette NB, Kim S, Knauber T, Chinigo GM, Blakemore DC, MacMillan DWC.   +6 more
europepmc   +1 more source

Access to and unexplored reactivity of nickel-bound 5-membered O- and N-heterocyclic arynes <i>via</i> computational insight. [PDF]

Chem Sci
Pullarat SS, Younis AA, Morais GN, Fitzsimmons MC, Belli RG, Humke JN, Chen S, Roberts CC.   +7 more
europepmc   +1 more source

Novel Substituted Tetrahydropyrrolooxazolones as RIPK1 Inhibitors. [PDF]

ACS Med Chem Lett
Rong J, Liang SH.
europepmc   +1 more source

Gold Single‐Atom Catalysts Enable Selective Shuttle Hydrochlorination of Alkynes

Angewandte Chemie International Edition, EarlyView.
Gold single‐atom catalysts on activated carbon enable heterogeneous shuttle hydrochlorination of terminal alkynes to vinyl chlorides with high chemo‐ and stereo‐selectivity thanks to cooperation between Au(I) sites and the support. The catalytic system combines broad substrate compatibility, simplified separation, and recoverability, paving the way for
Marc‐Eduard Usteri, Eva J. Meeus, Christian Zachau, Seung‐Eun Choi, Aram Bugaev, Milivoj Plodinec, Sharon Mitchell, Bill Morandi, Javier Pérez‐Ramírez   +8 more
wiley   +1 more source

Red-shifting squaraine dyes in the near-infrared region using perimidine heterocycles: synthesis and optical properties. [PDF]

RSC Adv
Sarasiya S, Henary M.
europepmc   +1 more source

Thinking Outside the Binding Site: A Self‐Encapsulating Kinase Inhibitor Remodels Its Pocket to Achieve Selectivity

Angewandte Chemie International Edition, EarlyView.
To make exceptionally effective drugs, thinking “outside the binding site” is required. This work reveals that counterintuitive targeting of a kinase‐conserved region can lead to highly selective binding. Inhibitor discovery coupled to x‐ray crystallography shows that a network of noncanonical interactions and long‐range effects of distant unique amino
Nico J. Seidler, Monica R. MacDonald, Athina A. Moschopoulou, Sahba Cunningham, Tess M. Weber, Nader N. Nasief, Lorenz Mayer, Frederik W. Hacker, Ekaterina Hermann, Mareike B. Möllers, Yuliia Skliarenko, Tahereh Damghani, Abid N. Manzar, Kaly S. Lin, Ramona Rudalska, Marcia I. Goettert, Lars Zender, Daniel Dauch, Michael Forster, Stefan A. Laufer, David E. Heppner   +20 more
wiley   +1 more source

A photochemical strategy for pyrazole to imidazole conversion. [PDF]

Chem Sci
Wei Y, Kasama K, Igartua A, Yildiz DB, Ceuninck A, Dos Santos T, Büttner C, Thevenet D, Bossart M, Derdau V, Méndez M, Jubault P, Poisson T, Roure B, Leonori D.   +14 more
europepmc   +1 more source

Aza‐Büchner–Curtius–Schlotterbeck Reaction Enables Selective Construction of Quaternary Carbon Centers

Angewandte Chemie International Edition, EarlyView.
We introduce the Aza‐Büchner–Curtius–Schlotterbeck (ABCS) reaction: A mild, catalyst‐free method for homologating aryl imines. Diverging from the traditional BCS mechanism, the diazo intermediate undergoes selective C─C insertion to form an all‐carbon quaternary center.
Simon O. Angerer, Vincent George, Aryaman Pattanik, Gaia Carpentiero, Tereza Morcinková, Julia Rehbein, Burkhard König   +6 more
wiley   +1 more source

True Closed-Loop Recyclable Hydrogels Enabled by Imine Boronic Ester Crosslinking. [PDF]

Adv Mater
King JA, Litterio JM, Larmore SP, Lopez SA, Schmidt-Rohr K, Alzate-Sánchez DM.   +5 more
europepmc   +1 more source