Results 181 to 190 of about 28,367 (257)

Intramolecular Nickel-Catalyzed Reductive Coupling: Enantioselective Synthesis of Tetrahydroisoquinolines and Related Heterocycles. [PDF]

Angew Chem Int Ed Engl
Bender T, Leutzsch M, Sell Y, Fürstner A.   +3 more
europepmc   +1 more source

A unified platform for the rapid assembly of glutarimides for Cereblon E3 ligase modulatory drugs. [PDF]

Nat Commun
Whalley DM, Lorthioir O, Anderson NA, Braybrooke E, Coote SC, Demanze S, Douglas HL, Putra OD, Proctor K, Si Y, Staniland S, Stokes S, Woodhouse A.   +12 more
europepmc   +1 more source

Interfacial Mn‐Carbon Nitride Synergy Enables Selective Photocatalytic C─H Chlorination via Single‐Atom Catalysis

Angewandte Chemie International Edition, EarlyView.
A manganese single‐atom photocatalyst on functionalised carbon nitride enables selective visible‐light‐driven C(sp2)─H chlorination. DFT‐supported mechanistic studies indicate that photoinduced charge separation activates NCS, while isolated Mn sites stabilize Mn─Cl intermediates at the catalyst interface.
Jaro Vanderghinste, Prakash Kumar Sahoo, Xinbang Wu, Thanh Huyen Vuong, Anna Rokicińska, Susanna Monti, Giovanni Barcaro, Alina Skorynina, Aleksander Jaworski, Vivien Michaelis, Jabor Rabeah, Julia Bornhorst, Laura Simonelli, Piotr Kuśtrowski, Adam Slabon, Paul J. Dyson, Shoubhik Das   +16 more
wiley   +1 more source

Redox-Divergent Reactivity of a Gallium(I) Ambiphile toward an Allene, a Diyne, and Ph3PCN2. [PDF]

Inorg Chem
Schreiner SHF, Ludwig JN, Rüffer T, Hansmann MM, Kretschmer R.   +4 more
europepmc   +1 more source

The Heterocycle Isostere Explorer: A Computational Tool for the Discovery of Novel Aromatic Heterocyclic Isosteres. [PDF]

J Med Chem
Holland MTO, Sebastián-Pérez V, Bradley AR, Duarte F, Brennan PE.   +4 more
europepmc   +1 more source

Dual‐Function Cosubstrates Enable Threonine Dehydrogenase‐Driven Chemoenzymatic Pyrrole Synthesis

Angewandte Chemie International Edition, EarlyView.
Classical Knorr chemistry meets contemporary biocatalysis. Threonine dehydrogenase generates aminoacetone from l‐threonine, which is directly intercepted in a chemoenzymatic Knorr pyrrole synthesis. A dual‐function β‐dicarbonyl substrate serves as both pyrrole precursor and hydride acceptor for integrated NAD+ recycling, affording substituted pyrroles ...
Valentina Jurkaš, Fabian M. Kulier, Jorge González‐Rodríguez, Carlotta Chiesa, Peter Both, Peter Šiška, Fabio Parmeggiani, Florian Rudroff, Margit Winkler   +8 more
wiley   +1 more source

Bidentate Metal-Binding Motifs in US FDA Approved Small Molecule Drugs. [PDF]

J Med Chem
Njardarson JT, Tomat E.
europepmc   +1 more source

Visible-light-induced trifluoroacetylation reaction of electron-deficient nitrogen heterocycles. [PDF]

Front Chem
Li Y, An J, Wei Q, Yang H, Li X, Sun K, Cao Z, Chen X, Qu L, Yu B.   +9 more
europepmc   +1 more source

Heterocycle-Tethered Aurones: Synthesis and Evaluation of α-Glucosidase Inhibition. [PDF]

Biomed Res Int
Kobzar OL, Popova AV, Bondarenko SP, Mrug GP, Vovk AI, Frasinyuk MS.   +5 more
europepmc   +1 more source

Design rules for tuning charge-transfer emission in donor-acceptor nanohoops. [PDF]

Chem Sci
Bailey GM, Nguyen EQ, Sheldon MA, Zakharov LN, Jasti R.   +4 more
europepmc   +1 more source