Results 181 to 190 of about 27,695 (265)

Adaptive Hydrogenation of Alkynes Using CO as a Molecular Trigger to Selectively Produce Alkanes or Z‐Alkenes

Angewandte Chemie, EarlyView.
One catalyst for two products: CO acts as a molecular trigger for adaptive alkyne hydrogenation using supported Pd nanoparticles. The catalyst reversibly switches between the formation of alkanes under H2 and Z‐alkenes under H2/CO for 37 structurally diverse alkynes.
Manisha Durai, Lachlan Sharp‐Bucknall, Tim Alexander Schubert, Jacob Johny, John‐Tommes Krzeslack, Walid Hetaba, Walter Leitner, Alexis Bordet   +7 more
wiley   +1 more source

Bidentate Metal-Binding Motifs in US FDA Approved Small Molecule Drugs. [PDF]

J Med Chem
Njardarson JT, Tomat E.
europepmc   +1 more source

TADF‐Active Tetrazole Luminophores for Visible‐Light Functionalization of Nanoparticles and Surfaces

Angewandte Chemie, EarlyView.
A series of tetrazoles are reported that undergo 1,3‐dipolar cycloadditions with alkene and alkyne substrates, generating (dihydro)pyrazole products that exhibit thermally activated delayed fluorescence (TADF). The “photo‐click” reactivity of these tetrazoles is leveraged to functionalize nanoparticles and surfaces with TADF‐active chromophores ...
Ryoga Hojo, Katrina Bergmann, Siyuan L. Xie, Connor S. Durfy, William L. Primrose, Athan T. Gogoulis, Seja A. Elgadi, Mitchell J. Demchuk, Thomas Kalab, Peiqi Hu, Eva M. Nichols, Zachary M. Hudson   +11 more
wiley   +1 more source

A unified platform for the rapid assembly of glutarimides for Cereblon E3 ligase modulatory drugs. [PDF]

Nat Commun
Whalley DM, Lorthioir O, Anderson NA, Braybrooke E, Coote SC, Demanze S, Douglas HL, Putra OD, Proctor K, Si Y, Staniland S, Stokes S, Woodhouse A.   +12 more
europepmc   +1 more source

Modular Access to α‐Tertiary Amines: Electrochemical Tandem Di‐Functionalization of Olefins With Ammonia Surrogates and Amino Acids

Angewandte Chemie, EarlyView.
A metal‐ and oxidant‐free electrochemical multicomponent di‐functionalization strategy that rapidly converts 1,1‐disubstituted alkenes into α‐tertiary primary amines with simultaneous installation of bio‐relevant sulfur or selenium motifs was devised for late‐stage functionalization. ABSTRACT Quaternary carbon centers, especially those bearing nitrogen,
Adrija Ghosh, Tarun, Sven Erik Peters, Lutz Ackermann, Debasis Banerjee   +4 more
wiley   +1 more source

The Heterocycle Isostere Explorer: A Computational Tool for the Discovery of Novel Aromatic Heterocyclic Isosteres. [PDF]

J Med Chem
Holland MTO, Sebastián-Pérez V, Bradley AR, Duarte F, Brennan PE.   +4 more
europepmc   +1 more source

Nitrogen Radical Photocatalysed Reduction of Nitrous Oxide

Angewandte Chemie, EarlyView.
This work offers the first example of reduction of the potent greenhouse gas N2O to the benign products N2 and O(Bpin)2 using a nitrogen‐based catalyst. The active catalyst is shown to be a nitrogen‐based radical which operates under photocatalytic conditions.
Reece Lister‐Roberts, Agamemnon E. Crumpton, Meera Mehta   +2 more
wiley   +1 more source

Tunable Oxygen Connectivity in Carbaporphyrinoid Polymers on Metal Surfaces

Angewandte Chemie, EarlyView.
Hydroxyl‐functionalized dicarbaporphyrinoid polymers synthesized on Au(111) enable tunable oxygen‐mediated connectivity under UHV conditions. Thermal activation yields one‐dimensional hydroxyl‐terminated polymers that can selectively evolve into either covalently‐linked dibenzo‐p‐dioxane architectures through intermolecular C–O–C coupling or two‐fold ...
Alberto Martínez‐Bajo, Maxence Urbani, Ana Barragán, Óscar Jover, Elena Pérez‐Elvira, Ilaria Tomei, Claudio Goletti, Alejandro Jiménez‐Martín, Aurelio Gallardo, Koen Lauwaet, David Écija, Diego Soler‐Polo, Marco Di Giovannantonio, Tomás Torres, José I. Urgel   +14 more
wiley   +1 more source

Design rules for tuning charge-transfer emission in donor-acceptor nanohoops. [PDF]

Chem Sci
Bailey GM, Nguyen EQ, Sheldon MA, Zakharov LN, Jasti R.   +4 more
europepmc   +1 more source

Heterocycle-Tethered Aurones: Synthesis and Evaluation of α-Glucosidase Inhibition. [PDF]

Biomed Res Int
Kobzar OL, Popova AV, Bondarenko SP, Mrug GP, Vovk AI, Frasinyuk MS.   +5 more
europepmc   +1 more source