Results 291 to 300 of about 169,803 (413)

Engineering Bodipy‐Based Metal–Organic Frameworks for Efficient Full‐Spectrum Photocatalysis in Amide Synthesis

open access: yesAngewandte Chemie, EarlyView.
Three highly stable bodipy‐based metal–organic frameworks (BMOFs) were synthesized by treating dicarboxyl‐functionalized bodipy ligands with Zr‐oxo clusters. Featuring the distinct bodipy scaffold in the framework, these BMOFs displayed high reactivity in heterogenous photocatalytic C─H bond activation of N,N‐dimethylanilines to access amides under ...
Binhui Liu   +9 more
wiley   +1 more source

Access to N‐Monofluoromethylated (Thio)Carbamates, Formamides, Alkynamides, and Related Derivatives

open access: yesAngewandte Chemie, EarlyView.
The first general synthetic access to N‐CH₂F and N‐CHRF carbamates, thiocarbamates, formamides, alkynamides, and related compounds is disclosed. The method involves the direct synthesis of carbamoyl fluoride building blocks from readily available amines, followed by their derivatization. Abstract This work presents the first general synthetic access to
Filip G. Zivkovic   +3 more
wiley   +1 more source

Desulfurizative Fluorination of N‐CF3 Thioformamides for the Efficient Synthesis of N(CF3)(CF2H) Amines with Enhanced Stability

open access: yesAngewandte Chemie, EarlyView.
We present the first general synthetic strategy for accessing N(CF3)(CF2H) amines, which display a 2000‐fold increase in stability over N‐CF3 amines. The compounds are synthesized through a desulfurization–fluorination of N‐CF3 thioformamides. Abstract With poor metabolic stability being a major cause of failure in drug development, there is a pressing
Gina Wycich   +3 more
wiley   +1 more source

A Bench‐Stable Fluorophosphine Nickel(0) Complex and Its Catalytic Application

open access: yesAngewandte Chemie, EarlyView.
We herein present the synthesis of a bench‐stable Ni(0) complex, [Ni(PFPh2)4], stabilized by vastly underexplored fluorophosphine ligands. The application of [Ni(PFPh2)4] in Suzuki–Miyaura and Kumada‐Tamao‐Corriu cross‐coupling reactions as well as in Buchwald–Hartwig C─N bond formation reactions, indicates its promising potential as alternative to ...
Franziska Flecken   +3 more
wiley   +1 more source

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