Molecules, 2017 Thirty six novel heterocyclic derivatives of ethyl 2-(2-pyridylacetate) were efficiently synthesized. The new compounds involve the linkage of a 2-pyridyl ring with thiosemicarbazide (compounds 1–7), 1,2,4-triazole (compounds 1a–7a), 1,3,4-thiadiazole ...
Daniel Szulczyk +7 more
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Three-coordinate iron(II) expanded ring N-heterocyclic carbene complexes [PDF]
, 2016 A sterically demanding seven-membered expanded ring N-heterocyclic carbene (NHC) ligand allows access to rare examples of three-coordinate iron(II)-NHC complexes incorporating only halide coligands of the general formula [Fe(NHC)X 2 ] (NHC = 7-DiPP; X ...
David J. Evans +6 more
core +5 more sources
Efficient Synthesis and Bioactivity of Novel Triazole Derivatives
Molecules, 2018 Triazole pesticides are organic nitrogen-containing heterocyclic compounds, which contain 1,2,3-triazole ring. In order to develop potential glucosamine-6-phosphate synthase (GlmS) inhibitor fungicides, forty compounds of triazole derivatives were ...
Boyang Hu +5 more
doaj +2 more sources
Design and Synthesis of Structurally Modified Analogs of 24Z-Isomasticadienonic Acid with Enhanced Anti-Proliferative Activity [PDF]
MoleculesΤriterpenic acids represent a prominent class of bioactive compounds, with a wide range of biological properties, including anti-inflammatory, antiviral, and anticancer effects. Among them, 24Z-isomasticadienonic acid (IMNA), a major constituent of Chios
Panagiota Stamou +5 more
doaj +2 more sources
Design, Synthesis and Antiparasitic Evaluation of Click Phospholipids
Molecules, 2021 A library of seventeen novel ether phospholipid analogues, containing 5-membered heterocyclic rings (1,2,3-triazolyl, isoxazolyl, 1,3,4-oxadiazolyl and 1,2,4-oxadiazolyl) in the lipid portion were designed and synthesized aiming to identify optimised ...
George E. Magoulas +21 more
doaj +1 more source
Synthesis, characterization, and antimicrobial evaluation of new Schiff bases derived from vanillic acid conjugated to heterocyclic 4H-1,2,4-triazole-3-thiol [PDF]
Pharmacia, 2023 A multistep synthesis was established for the preparation of a new vanillic acid-1, 2, 4-1triazole-3-thiol conjugate (4). Finally, several aromatized aldehydes reacted with compound (4) to produce Schiff bases derivatives (5–11).
Noor Ali Hussein Sabzi +1 more
doaj +3 more sources
Synthesis and Antioxidant Activity of New Catechol Thioethers with the Methylene Linker
Molecules, 2022 Novel catechol thio-ethers with different heterocyclic substituents at sulfur atom were prepared by reacting 3,5-di-tert-butyl-6-methoxymethylcatechol with functionalized thiols under acidic conditions. A common feature of compounds is a methylene bridge
Ivan V. Smolyaninov +7 more
doaj +1 more source
Results in Chemistry, 2022 The preparation and spectral identification of metal complexes for Pd(II) and Pt (IV) ions with new heterocyclic azo dye as ligand 2′[2′-(1-Hydroxy-4-methyl phenyl)azo] −1-methyl imidazole (HPA-1-MeI) were prepared by reacting diazonium chloride salt ...
Sajjad H. Jawad, Khalid J. Al-Adilee
doaj +1 more source
Antinociceptive grayanane-derived diterpenoids from flowers of Rhododendron molle
Acta Pharmaceutica Sinica B, 2020 Twelve new grayanoids (1−12) along with five known compounds were isolated from flowers of Rhododendron molle. Their structures were fully characterized using a combination of spectroscopic analyses, computational calculations, and single crystal X-ray ...
Yong Li +7 more
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N-heterocyclic germylenes: structural characterisation of some heavy analogues of the ubiquitous N-heterocyclic carbenes [PDF]
, 2019 The X-ray crystal structures of three N-heterocyclic germylenes (NHGes) have been elucidated including the previously unknown 1,3-bis(2,6-dimethylphenyl)diazagermol-2-ylidene (1).
Dodds, Christopher A. +2 more
core +2 more sources